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Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses

  • US 7,166,478 B2
  • Filed: 03/12/2002
  • Issued: 01/23/2007
  • Est. Priority Date: 03/12/2002
  • Status: Expired due to Term
First Claim
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1. A labeling reagent for labeling a target, said labeling reagent comprising a marker moiety M and a reactive group R
M-Rwherein said marker moiety M and said reactive group R are covalently linked together by a linker arm comprising a backbone which comprises one or more carbon atoms, wherein said backbone further comprises one or more peptide bonds, said M comprising at least one moiety that comprises a ligand, a dye, or both a ligand and a dye;

  • and wherein said target is labeled by forming a carbon-carbon bond between a carbon atom in said target and a carbon atom in said labeling reagent by means of said reactive group R.

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