Hyperthermia treatment and probe therefor

• US 7,167,741 B2
• Filed: 12/14/2001
• Issued: 01/23/2007
• Est. Priority Date: 06/15/2000
• Status: Expired due to Term

• Current Assignee: Monteris Medical Incorporated (Monteris Medical US, Inc.)
• Original Assignee: Monteris Medical Incorporated (Monteris Medical US, Inc.)
• Inventors: Tyc, Richard, Torchia, Mark G., Pacak, John S.
• Primary Examiner(s): Casler; Brian L.
• Assistant Examiner(s): JUNG, WILLIAM C
• Application Number:
  US10/014,846
• Publication Number:
  US 20020193682A1
• Time in Patent Office: 1,866 Days
• Field of Search: 601 1- 5, 600/437, 600/439, 600/407, 600/411, 600/425, 600/427
• US Class Current: 600/427
• CPC Class Codes: A61B 18/20 using laser
• CPC Class Codes: A61B 18/24 with a catheter A61B18/26, A61B18/28 take precedence
• CPC Class Codes: A61B 2018/00023 closed, i.e. without wound contact by the fluid
• CPC Class Codes: A61B 2018/00196 reciprocating lengthwise
• CPC Class Codes: A61B 2018/00636 Sensing and controlling the application of energy
• CPC Class Codes: A61B 2018/1861 with an instrument inserted into a body lumen or cavity, e.g. a catheter
• CPC Class Codes: A61B 2018/2005 with beam delivery through an interstitially insertable device, e.g. needle
• CPC Class Codes: A61B 2018/2277 with refractive surfaces
• CPC Class Codes: A61B 2090/374 NMR or MRI
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 90/36 Image-producing devices or illumination devices not otherwise provided for

Abstract

This surgical device uses a laser beam to coagulate tissue. The elongate device carries the beam through an optical fiber that has a chamfered end for deflecting the beam out of a distal end of the device at an angle. Tissue coagulation is monitored using a magnetic resonance imaging system that provides periodic tissue temperature data. A small fluid supply duct provides cooling fluid that expands to a gas near the distal end of the device, thereby cooling the tip.

Claims

1. A method for effecting treatment in a patient comprising:

identifying a volume in the patient the whole of which volume is to be heated to a required temperature, the volume being defined by a peripheral surface of the volume;

heating the volume within the patient by;

inserting a probe having a longitudinal axis and a distal end into the patient such that the distal end is in the volume;

sending laser energy through the probe;

deflecting the laser energy from the distal end of the probe at an angle from the longitudinal angle greater than zero, such that a heating effect of the probe lies in a disk-shaped area surrounding the axis;

directing the heat to define a heating zone that forms a limited angular orientation of heating within the disk-shaped area such that as the probe is rotated, the probe causes heating of different angular segments of the volume within the disk-shaped area;

with the probe at a fixed axial position, rotating the probe about the axis so that the heating zone lies in a selected segment;

wherein applying heat to the selected segment causes heat to be transferred from the segment into parts of the volume outside the segment surrounding the end of the probe; and

cooling the end of the probe so as to extract heat from the parts surrounding the probe by conduction of heat therefrom

wherein cooling the distal end of the probe so as to extract heat from the parts surrounding the probe by conduction of heat therefrom comprises;

directing fluid to the distal end of the probe through a supply duct in the probe;

vaporizing the fluid in an expansion zone of reduced pressure in the distal end of the probe;

retrieving the gas from the probe through a return duct in the probe that is between 200 and 250 times larger in cross-sectional area than the supply duct.

2. The method of claim 1 wherein cooling the end of the probe so as to extract heat from the parts surrounding the probe by conduction of heat therefrom comprises cooling the end of the probe sufficiently to prevent the end of the probe from heating tissue outside of the selected segment to the required temperature.

3. The method of claim 2 wherein cooling the end of the probe sufficiently to prevent the end of the probe from heating tissue outside of the selected segment to the required temperature comprises cooling the end of the probe sufficiently to prevent the end of the probe from coagulating tissue outside of the segment.

4. The method of claim 1 further comprising moving the end of the probe axially within the volume thereby moving the disk-shaped area axially within the volume from a first position to a second position.

5. The method of claim 1 further comprising operating a non-invasive detection system to monitor a series of temperatures of the peripheral surface of the volume for use as a factor in determining when to stop heating a segment.

6. The method of claim 1 wherein sending laser energy through the probe comprises sending laser energy through an optical fiber contained within the probe and wherein deflecting the laser energy from the distal end of the probe at an angle from the longitudinal angle greater than zero comprises deflecting the laser energy off of a light directing element proximate the distal end of the fiber.

7. The method of claim 1 further comprising controlling a flow rate of the fluid directed to the distal end such that the distal end of the probe is cooled to a temperature between zero and minus 20 degrees Celsius.

8. The method of claim 1 wherein sending laser energy through the probe comprises sending laser energy through the probe at a power level that decreases from an initial high level to a lower value for each segment heated.

9. The method of claim 1 wherein retrieving the gas from the probe through a return duct in the probe comprises retrieving the gas from the probe through a return duct having outward extents defined by inside surfaces of an outer wall of the probe.

10. The method of claim 9 wherein directing fluid to the distal end of the probe through a supply duct in the probe comprises directing fluid to the distal end of the probe through a supply duct defined by a tube attached to the inside surface of the outer wall of the probe.

11. The method of claim 10 further comprising receiving data from a temperature sensor mounted on the inside surface of the outer wall of the probe proximate the distal end.

12. The method of claim 9 wherein sending laser energy through the probe comprises sending laser energy through a medium attached to the inside surface of the outer wall of the probe.

13. The method of claim 1 wherein vaporizing the fluid in an expansion zone of reduced pressure in the distal end of the probe comprises passing the fluid through a restricting orifice at an end of the supply duct leading into the expansion zone.

14. The method according to claim 13 wherein passing the fluid through a restricting orifice at an end of the supply duct leading into the expansion zone comprises passing the fluid through a restricting orifice formed by a reduced necking of a tube defining the supply duct.

15. The method according to claim 14 wherein passing the fluid through a restricting orifice formed by a reduced necking of a tube defining the supply duct comprises passing the fluid through a restricting orifice disposed distally of an end of an outer tube that defines the return duct.

16. The method according to claim 1 wherein sending laser energy through the probe comprises sending laser energy through an optical fiber contained within the probe and wherein deflecting the laser energy from the distal end of the probe at an angle from the longitudinal angle greater than zero comprises deflecting the laser energy off of a chamfered end of the optical fiber located in the expansion zone.

17. The method according to claim 16 wherein deflecting the laser energy off of a chamfered end of the optical fiber located in the expansion zone comprises deflecting the laser energy off of a chamfered end of the optical fiber that is chamfered at approximately 45 degrees to the longitudinal axis of the probe.

18. The method according to claim 16 wherein deflecting the laser energy off of a chamfered end of the optical fiber located in the expansion zone comprises deflecting the laser energy off of a chamfered end of the optical fiber having a coating that reflects light at two different wavelengths.

19. The method of claim 1 further comprising receiving data from a temperature sensor located at the distal end of the probe.

20. The method of claim 1 further comprising controlling a temperature at the distal end of the probe by varying the pressure of the fluid directed to the distal end of the probe.

21. A method for effecting treatment in a patient comprising:

identifying a volume in the patient to be heated to a required temperature;

inserting a distal end of a probe into the volume using a position control system;

heating the volume by directing energy out the distal end of the probe into the volume; and

cooling the distal end of the probe by

directing cooling fluid to an expansion zone in the distal end of the probe through a supply duct defined by the probe;

allowing the cooling fluid to undergo a phase change to gas in the expansion zone; and

retrieving the gas through a return duct defined by the probe wherein heating the volume by directing energy out the distal end of the probe into the volume comprises directing laser energy through an optical fiber contained within the probe and deflecting the laser energy off of a chamfered end of the optical fiber located in the expansion zone.

22. The method of claim 21 wherein cooling the distal end of the probe comprises cooling the distal end of the probe to between zero and minus 20 degrees Celsius.

23. The method of claim 21 wherein retrieving the gas through a return duct defined by the probe comprises retrieving the gas from the probe through a return duct having outward extents defined by inside surfaces of an outer wall of the probe.

24. The method of claim 23 wherein directing cooling fluid to an expansion zone in the distal end of the probe through a supply duct defined by the probe comprises directing fluid to the expansion zone in the distal end of the probe through a supply duct defined by a tube attached to the inside surface of the outer wall of the probe.

25. The method of claim 23 wherein heating the volume by directing energy out the distal end of the probe into the volume comprises sending energy through an energy supply conduit attached to the inside surface of the outer wall of the probe.

26. The method of claim 21 wherein allowing the cooling fluid to undergo a phase change to gas in the expansion zone comprises passing the cooling fluid through a restricting orifice at a distal end of the supply duct.

27. The method of claim 26 wherein passing the cooling fluid through a restricting orifice at a distal end of the supply duct comprises passing the cooling fluid through a restricting orifice at a distal end of the supply duct formed by a reduced necking of a tube defining the supply duct.

28. The method of claim 27 wherein directing cooling fluid to an expansion zone in the distal end of the probe through a supply duct defined by the probe comprises directing fluid to the distal end of the probe through a supply duct defined by a tube attached to an inside surface of an outer wall of the probe.

29. The method of claim 21 wherein deflecting the laser energy off of a chamfered end of the optical fiber located in the expansion zone comprises deflecting the laser energy off of an end of the optical fiber chamfered on the order of 45 degrees.

30. The method of claim 21 wherein deflecting the laser energy off of a chamfered end of the optical fiber located in the expansion zone comprises deflecting the laser energy off of a chamfered end of the optical fiber having a coating that reflects light at two different wavelengths.

31. The method of claim 21 further comprising receiving data from a temperature sensor located at the distal end of the probe.

32. The method of claim 21 further comprising receiving data from a temperature sensor mounted on the inside surface of the outer wall of the probe proximate the distal end.

33. The method of claim 21 further comprising controlling a temperature at the distal end of the probe by varying the pressure of the fluid directed to the expansion zone in the distal end of the probe.

34. The method of claim 21 wherein heating the volume by directing laser energy through the probe and out the distal end of the probe into the volume comprises directing laser energy through an optical fiber extending through an outer tube of the probe and into a transparent capsule distal of the outer tube and enclosing a distal end of the outer tube.