Thermal sensor
First Claim
Patent Images
1. A chemical preconcentrator, comprising:
- a substrate having plural sample chambers, each at least partially bounded by the substrate and each associated with a separate reaction chamber that is at least partially bounded by the substrate, a passageway extending through the substrate from each sample chamber into the associated reaction chamber to define an inlet for conducting fluid from the sample chamber into the reaction chamber, a reaction surface within each reaction chamber and an orifice in the substrate adjacent the reaction surface defining an outlet from the reaction chamber;
a sorbant deposited on the reaction surface;
a heat transducer in the substrate between the sample chamber and the reaction chamber in proximity to the reaction surface and configured for heating the reaction surface; and
a control system configured for energizing separately selected heat transducers.
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Accused Products
Abstract
A thermal sensor has a substrate defining a reaction chamber. The reaction chamber has an inlet for conducting sample into the reaction chamber, a reaction surface and an orifice adjacent the reaction surface defining an outlet from the reaction chamber. The reaction surface is coated with a sorbant for binding agents in the sample. A heat transducer in the substrate and in proximity to the reaction surface is configured for heating the reaction surface.
18 Citations
23 Claims
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1. A chemical preconcentrator, comprising:
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a substrate having plural sample chambers, each at least partially bounded by the substrate and each associated with a separate reaction chamber that is at least partially bounded by the substrate, a passageway extending through the substrate from each sample chamber into the associated reaction chamber to define an inlet for conducting fluid from the sample chamber into the reaction chamber, a reaction surface within each reaction chamber and an orifice in the substrate adjacent the reaction surface defining an outlet from the reaction chamber; a sorbant deposited on the reaction surface; a heat transducer in the substrate between the sample chamber and the reaction chamber in proximity to the reaction surface and configured for heating the reaction surface; and a control system configured for energizing separately selected heat transducers. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method of analyzing agents in a sample, comprising the steps of:
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(a) providing a chemical preconcentrator comprising a substrate having a sample chamber and a reaction chamber, each at least partly bounded by the substrate, a passageway from the sample chamber through the substrate into the reaction chamber to define an inlet to the reaction chamber from the sample chamber, a reaction surface In the reaction chamber having a sorbant deposited thereon, and an orifice adjacent the reaction surface defining an outlet from the reaction chamber; (b) introducing a sample liquid from the sample chamber into the reaction chamber through the inlet and allowing the sample liquid to remain in the reaction chamber for a period of time sufficient for agents contained in the sample to be bound to the sorbant and thereby preconcentrate the agents; (C) energizing a heat transducer to heat the reaction surface and to thereby volatilize the agents such that the volatilized agents exit the reaction chamber through the orifice; (d) capturing the volatilized agents in an analyzer to characterize the agents. - View Dependent Claims (10, 11, 12, 13)
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14. Apparatus for detecting agents in a fluid sample, comprising:
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preconcentrator means for binding agents in the sample to a sorbant-coated reaction surface in a reaction chamber in said preconcentrator means, said preconcentrator means having plural sample chambers and plural reaction chambers, each sample chamber associated with a reaction chamber and each reaction chamber having a sorbant-coated reaction surface, and an inlet from each sample chamber into the associated reaction chamber, and an outlet from each reaction chamber defined by an orifice in said preconcentrator means; heating means for heating selected reaction surfaces to volatilize agents bound to the sorbant in selected chambers, said heating means including a heating element located in the preconcentrator means between the sample chamber and the selected reaction chamber; controller means for energizing the heating means at a predetermined time and at a controlled rate; analyzer means for receiving agents volatilized from the reaction chamber and characterizing the agents. - View Dependent Claims (15)
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16. Apparatus for preconcentrating compounds in a sample, comprising:
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a unitary integrated circuit substrate member having plural reaction chambers and a sample chamber associated with each reaction chamber, each reaction chamber having a heat transducer in proximity to an interior surface thereof defining a reaction surface and such that the heat transducer is capable of heating the reaction surface, said heat transducer positioned between the sample chamber and the reaction chamber, and the substrate member further defining a passageway from the sample chamber to the reaction chamber through which compounds are conducted into the reaction chamber from the sample chamber and an orifice through which compounds are conducted Out of the reaction chamber; a sorbant deposited on the reaction surface; a control system connected to each heat transducer and configured to energize selected heat transducers to selectively heat individual reaction surfaces. - View Dependent Claims (17, 18, 19, 20)
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21. A method of detecting the presence of a chemical in a sample, comprising the steps of:
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(a) inducing a flow of a sample from a sample chamber through a passageway and into a reaction chamber of a chemical preconcetrator, the preconcentrator comprising a unitary substrate member that at least partially bounds plural sample chambers and plural reaction chambers, each sample chamber associated with a reaction chamber, and the substrate member having a heat transducer between each sample chamber and the associated reaction chamber in proximity to an interior surface of the reaction chamber defining a reaction surface within each reaction chamber, and a sorbant deposited on each reaction surface; (b) allowing the sample to remain in the reaction chamber for a period of time sufficient to bind agent in the sample to the sorbant; (c) heating the reaction surface in a selected reaction chamber to volatilize the agent; (d) capturing and detecting the agent volatilized from the selected reaction chamber in an analyzer. - View Dependent Claims (22, 23)
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Specification