Graft delivery system

• US 7,175,336 B2
• Filed: 01/26/2001
• Issued: 02/13/2007
• Est. Priority Date: 01/26/2001
• Status: Expired due to Fees

• Current Assignee: Depuy Acromed Incorporated (Johnson & Johnson)
• Original Assignee: Depuy Acromed Incorporated (Johnson & Johnson)
• Inventors: Naoi, Yukiko, Urbahns, David, Kadiyala, Sudhakar, Kapec, Jeffrey, Tanaka, Kazuna, Voellmicke, John C., Connolly, Stephen W., Bruder, Scott P.
• Primary Examiner(s): SOOHOO, TONY GLEN
• Application Number:
  US09/771,433
• Publication Number:
  US 20040167617A1
• Time in Patent Office: 2,209 Days
• Field of Search: 137/606, 137/602, 604/83, 604/82, 604/416, 366/160.4, 366/189, 366/190
• US Class Current: 366/160.4
• CPC Class Codes: A61B 2017/00495 for two-component glue
• CPC Class Codes: A61F 2/4405 for apophyseal or facet joints, i.e. between adjacent spinous or transverse processes devices implanted between spinous or transverse processes A61B17/7062
• CPC Class Codes: A61F 2/4455 for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages intervertebral discs A61F2/442
• CPC Class Codes: A61F 2/4601 for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity
• CPC Class Codes: A61F 2/4644 Preparation of bone graft, bone plugs or bone dowels, e.g. grinding or milling bone material bone material A61F2/28; disintegrating or milling devices B02C
• CPC Class Codes: A61F 2002/2835 Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
• CPC Class Codes: A61F 2002/3071 Identification means; Administration of patients
• CPC Class Codes: A61F 2250/0087 colour-coded
• CPC Class Codes: A61J 1/2031 having openings brought into alignment
• CPC Class Codes: A61J 1/2037 having valve means
• CPC Class Codes: A61J 1/2055 having gripping means
• CPC Class Codes: A61J 1/2058 having multiple connecting ports
• CPC Class Codes: A61J 1/2062 with directional valves
• CPC Class Codes: A61J 1/2075 for external venting
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents

Abstract

The invention relates to a manifold for mixing biomedical fluids having superior stability and minimal susceptibility to clotting.

Claims

1. An apparatus comprising a fluid retention chamber having an opening, and a manifold comprising:

a) an output port adapted for attachment to a fluid retention chamber, the port having at least one opening,

b) first and second input ports, each port adapted for attachment to a delivery syringe, each input port having an opening, and

c) first and second tubes, each tube having a sterile inner surface, and entry and exit portions,

d) a continuous base having an upper and a lower surface, wherein each port is located upon the base and extends upward from the upper surface, and

e) first and second delivery syringes, each syringe having a bore, a syringe opening and a plunger contained within the bore,

wherein the syringe opening of each syringe is attached to the opening of the respective input port,

the entry portion of the first tube being in fluid communication with the opening of the first input port, the entry portion of the second tube being in fluid communication with the opening of the second input port,

the exit portion of each tube being in fluid communication with the at least one opening of the output port,

wherein each port opening has a centerpoint at the upper surface of the base, wherein the three centerpoints define a triangle.

2. The apparatus of claim 1 wherein the triangle defines an angle α

of between 5 and 90 degrees.

3. The apparatus of claim 2 wherein the angle α

is between 5 and 45 degrees.

4. The apparatus of claim 2 wherein the angle α

is between 10 and 30 degrees.

5. The apparatus of claim 1 wherein the plunger of each delivery syringe extends upward from the upper surface of the base.

6. The apparatus of claim 1 wherein the first delivery syringe contains a first fluid comprising PRP, and the second delivery syringe contains a first fluid comprising thrombin.