Therapeutic delivery balloon

• US 7,179,251 B2
• Filed: 01/17/2001
• Issued: 02/20/2007
• Est. Priority Date: 01/17/2001
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Palasis, Maria
• Primary Examiner(s): Thanh; LoAn H.
• Application Number:
  US09/760,807
• Publication Number:
  US 20020095114A1
• Time in Patent Office: 2,225 Days
• Field of Search: 604/93.01, 604/96.01, 604/97.01, 60410101-10103, 604/102.01, 60410301-10302, 60410305-10306, 604/103.11, 604/103.08, 606/915, 606/919, 606/192, 606/194
• US Class Current: 604/509
• CPC Class Codes: A61M 2025/1013 with concentrically mounted balloons, e.g. being independently inflatable
• CPC Class Codes: A61M 2025/105 having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
• CPC Class Codes: A61M 25/104 used for angioplasty

Abstract

The present invention regards a therapeutic delivery balloon and includes a system for delivering therapeutic to an irregular interior vessel surface. This system includes a catheter having a proximal end, a distal end, and an internal lumen; a source of fluid in communication with the internal lumen of the catheter; and, a first inflatable balloon having an exterior surface, wherein the balloon is hyper-deformable, is in communication with the internal lumen of the catheter, and has an exterior surface in communication with a therapeutic when the balloon is in expanded state.

Claims

1. A system for delivering therapeutic to an irregular interior vessel surface comprising:

a catheter having a proximal end, a distal end, and a first internal lumen;

a source of fluid in communication with the first internal lumen of the catheter; and

a first inflatable balloon having an exterior surface and an interior surface,

the first inflatable balloon attached to the distal end of the catheter and in fluid communication with the first internal lumen of the catheter,

the first inflatable balloon having a measurable elasticity,

the exterior surface of the first inflatable balloon at least partially covered with a therapeutic when the first inflatable balloon is in an initial unexpanded state,

the interior surface of the first inflatable balloon free from contact with the therapeutic when the exterior surface of the first inflatable balloon is at least partially covered with the therapeutic when the first inflatable balloon is in an initial unexpanded state,

the exterior surface of the first inflatable balloon at least partially covered with a therapeutic when the first inflatable balloon is in an expanded state; and

a dilation bladder located within the first inflatable balloon,

the dilation bladder attached to the distal end of the catheter and in fluid communication with a second internal lumen of the catheter by way of a dilation bladder opening in the catheter,

the dilation bladder deformable from a non-inflated position to an inflated position,

the dilation bladder having a measurable elasticity, the elasticity of the first inflatable balloon being greater than the elasticity of the dilation bladder.

2. The system for delivering therapeutic of claim 1 wherein the exterior surface of the first inflatable balloon is contacting a therapeutic when the first inflatable balloon is in an initial unexpanded state.

3. The system for delivering therapeutic of claim 1 further comprising:

a source of therapeutic, the source of therapeutic in fluid communication with the exterior surface of the first inflatable balloon.

4. The system for delivering therapeutic of claim 1 wherein the first inflatable balloon is made with a latex material and wherein the source of fluid is adapted to control the rate of inflation of the balloon.

5. The system for delivering therapeutic of claim 1 wherein the first inflatable balloon is made with a silicone material and wherein the source of fluid is adapted to control the rate of inflation of the balloon.

6. The system for delivering therapeutic of claim 1 wherein the first inflatable balloon is made with a polyurethane material and wherein the source of fluid is adapted to control the rate of inflation of the balloon.

7. A device for delivering therapeutic to an irregular interior vessel surface comprising:

a catheter having a proximal end, a distal end, and an internal lumen;

a first inflatable balloon attached to the distal end of the catheter and in fluid communication with the internal lumen of the catheter, the first inflatable balloon having a measurable elasticity, the first inflatable balloon having an exterior surface and an interior surface, the exterior surface of the first inflatable balloon at least partially covered with a therapeutic, the first inflatable balloon being impervious to the therapeutic; and

a dilation bladder located within the first inflatable balloon, the dilation bladder attached to the distal end of the catheter and in fluid communication with a second internal lumen of the catheter by way of a dilation bladder opening in the catheter, the dilation bladder deformable from a non-inflated position to an inflated position.

8. The device of claim 7 further comprising:

a source of therapeutic, the source of therapeutic in fluid communication with the exterior surface of the first inflatable balloon.

9. A method for delivering therapeutic to an irregular interior vessel surface of a patient comprising:

inserting an expandable first membrane attached to a distal end of a catheter into the vessel of the patient, the expandable first membrane having an exterior surface in contact with therapeutic and having a measurable elasticity;

positioning the expandable first membrane at the irregular interior vessel surface within the patient;

forcing a fluid into the expandable first membrane after positioning the expandable first membrane at the irregular interior vessel surface to inflate the expandable first membrane, the expandable first membrane becoming juxtaposed to and replicating the irregular interior surface of the vessel of the patient; and

,

after positioning the expandable first membrane at the irregular interior surface of the vessel within the patient, inflating a dilation bladder located within the expandable first membrane, the dilation bladder having a measurable elasticity, the elasticity of the first inflatable balloon being greater than the elasticity of the dilation bladder, the dilation bladder attached to the distal end of the catheter.

10. The method of claim 9 wherein the exterior surface of the expandable first membrane is impervious to therapeutic.

11. The method of claim 9 wherein the fluid is a tracing fluid.

12. The method of claim 9 further comprising:

measuring the volume of fluid forced into the expandable membrane.