Implantable drug delivery device
First Claim
Patent Images
1. An implantable device for drug delivery comprising:
- a biodegradable body being comprised of at least one mounting aperture in said biodegradable body that is suitable for attaching said biodegradable body to a retina with a tack;
said body having a generally oval shape suitable to be placed adjacent to the plane of a retina,said oval shaoed body being curved such that it substantially conforms to the spherical curvature of at least portion of a recipient'"'"'s eye.
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Abstract
The invention is directed to an implantable device to enable delivery of drugs to the retina. The device minimizes stress to the retina by virtue of its softness and smooth shape that conform to the retina. Drugs are delivered by osmosis or by the device dissolving. It may be connected to an externally mounted pump and drug reservoir that control the amount of drug. It contains one or more holes that are positioned to deliver drugs to the desired location. Drugs may stimulate the retina to enable vision in blind patients. Drugs may be injected directly inside the eye by a trans-scleral pump and valve drug delivery device.
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Citations
12 Claims
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1. An implantable device for drug delivery comprising:
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a biodegradable body being comprised of at least one mounting aperture in said biodegradable body that is suitable for attaching said biodegradable body to a retina with a tack; said body having a generally oval shape suitable to be placed adjacent to the plane of a retina, said oval shaoed body being curved such that it substantially conforms to the spherical curvature of at least portion of a recipient'"'"'s eye. - View Dependent Claims (2, 3)
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4. An implantable device for drug delivery comprising:
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a biodegradable body being comprised of material having a hardness of about 50 or less on the Shore A scale as measured with a durometer; said body having a generally oval shape suitable to be placed adjacent to the plane of a retina, said oval shaped body being curved such that it substantially conforms to the spherical curvature of at least portion of a recipient'"'"'s eve.
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5. An implantable device for drug delivery comprising:
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a biologically inert hollow body defining at least one void, and wherein said inert body is comprised of material having a hardness of about 50 or less on the Shore A scale as measured with a durometer; said void containing at least one drug; said hollow body having a generally oval shape, said oval shaped body being curved such that it substantially conforms to the spherical curvature of at least a portion of a recipient'"'"'s eye.
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6. An implantable device for drug delivery comprising:
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a biologically inert body having a first side, an edge, and a second side, wherein said inert body is comprised of material having a hardness of about 50 or less on the Shore A scale as measured with a durometer; a first flexible layer on said first side of said inert body; said first flexible layer defining at least one mounting aperture.
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7. An implantable device for drug delivery to enable vision comprising:
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a biologically inert body having a first side, an edge, and a second side; a first flexible aver on said first side of said inert body suitable to contact neural tissue; said first flexible layer defining at least one delivery aperture; a second flexible layer on said second side; a third flexible layer on said edge; a drug delivery device delivering at least one drug to said at least one delivery aperture, wherein said at least one drug is composed of glutamate.
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8. An implantable device for drug delivery to enable vision comprising:
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a biologically inert body having a first side, an edge, and a second side; a first flexible layer on said first side of said inert body suitable to contact neural tissue; said first flexible layer defining at least one delivery aperture, wherein said at least one aperture further comprises an ordered array of one-hundred apertures in a ten by ten matrix; a second flexible layer on said second side; a third flexible layer on said edge; a drug delivery device delivering at least one drug to said at least one delivery aperture.
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9. An implantable device for drug delivery to enable vision comprising:
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a biologically inert body having a first side, an edge, and a second side; a first flexible layer on said first side of said inert body suitable to contact neural tissue; said first flexible layer defining at least one delivery aperture; a second flexible layer on said second side; a third flexible layer on said edge; a drug delivery device delivering at least one drug to said at least one delivery aperture, wherein said drug delivery device is comprised of; a reservoir; a pressure development device; at least one feeder tube that is attached to said inert body. - View Dependent Claims (10, 11)
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12. An implantable device for drug delivery to enable vision comprising:
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a biologically inert body having a first side, an edge, and a second side, wherein said inert body is comprised of material having a hardness of about 50 or less on the Shore A scale as measured with a durometer; a first flexible layer on said first side of said inert body suitable to contact neural tissue; said first flexible layer defining at least one delivery aperture, wherein said at least one aperture further comprises an ordered array of one-hundred apertures in a ten by ten matrix; a second flexible layer on said second side; a third flexible layer on said edge; a drug delivery device delivering at least one drug to said at least one delivery aperture.
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Specification