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Tape stripping methods for analysis of skin disease and pathological skin state

  • US 7,183,057 B2
  • Filed: 03/31/2004
  • Issued: 02/27/2007
  • Est. Priority Date: 03/31/2004
  • Status: Active Grant
First Claim
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1. A method of detecting expression of genes in the skin, comprising:

  • a) applying an adhesive tape to a target area of the skin in a manner sufficient to isolate an epidermal sample adhering to the adhesive tape, wherein the epidermal sample comprises nucleic acid molecules; and

    b) detecting expression of the nucleic acid molecules in the epidermal sample by determining a Ct value.

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