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Device and method for enhancing transdermal flux of agents being delivered or sampled

  • US 7,184,826 B2
  • Filed: 06/17/1997
  • Issued: 02/27/2007
  • Est. Priority Date: 06/18/1996
  • Status: Expired due to Fees
First Claim
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1. A device for piercing the stratum corneum of a body surface to form pathways through which an agent can be introduced or withdrawn, comprising a sheet having a least one opening therethrough and a plurality of blades extending downward therefrom, an adhesive anchor applied to at least one surface of said sheet, wherein said adhesive anchor helps prevent said sheet from being dislodged from said body surface, and an agent delivery or sampling device connected to said sheet and positioned to deliver or sample an agent through said opening, said agent delivery or sampling device being selected from the group consisting of an electrotransport device, a passive diffusion device, an osmotic device, and a pressure driven device, and wherein a plurality of blades has a substantially identical and uniform configuration.

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