Positive airway pressure system and method for treatment of sleeping disorder in patient

• US 7,186,221 B2
• Filed: 08/24/2005
• Issued: 03/06/2007
• Est. Priority Date: 08/14/2003
• Status: Expired due to Term

• Current Assignee: New York University
• Original Assignee: New York University
• Inventors: Norman, Robert G., Rapoport, David M.
• Primary Examiner(s): Marmor, II; Charles A
• Assistant Examiner(s): Natnithithadha; Navin
• Application Number:
  US11/210,568
• Publication Number:
  US 20060009708A1
• Time in Patent Office: 559 Days
• Field of Search: 600/529, 600531-538, 128/200.24, 128/204.18, 128/204.21, 128/204.22, 128/204.23, 128/204.26
• US Class Current: 600/538
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/087 Measuring breath flow
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/4809 Sleep detection, i.e. determining whether a subject is asleep or not
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61M 16/0066 Blowers or centrifugal pumps
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/06 Respiratory or anaesthetic masks
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0039 in the inspiratory circuit

Abstract

Described are a positive airway pressure system and method for treatment of a sleeping disorder in a patient. The system includes a generator, a sensor and a processing arrangement. The generator supplies airflow and applies a pressure at to an airway of a patient. The sensor measures data corresponding to patient'"'"'s breathing patterns. The processing arrangement analyzes the breathing patterns to determine whether the breathing patterns are indicative of at least one of the following patient'"'"'s states: (i) a regular breathing state, (ii) a sleep disorder breathing state, (iii) a REM sleep state and (iv) a troubled wakefulness state. The processing arrangement adjusts the applied pressure as a function of the patient'"'"'s state.

Claims

1. A positive airway pressure system for treatment of a sleeping disorder in a patient, comprising:

a generator supplying airflow and applying a pressure to an airway of a patient;

a sensor measuring data corresponding to patient'"'"'s breathing patterns; and

a processing arrangement analyzing the breathing patterns to determine whether the breathing patterns are indicative of one of the following patient'"'"'s states;

(i) a regular breathing state, (ii) a sleep disorder breathing state, (iii) a REM sleep state and (iv) a troubled wakefulness state, the processing arrangement adjusting the applied pressure as a function of the patient'"'"'s state,

wherein, when the breathing patterns indicate state (iv), the processing arrangement sets a target pressure value and controls the generator to adjust the pressure to approach the target pressure value.

2. The system according to claim 1, wherein, when the breathing patterns indicate one of states (i) and (ii) and (iii), the processing arrangement transfers control of the generator to a therapeutic pressure adjustment arrangement.

3. The system according to claim 1, wherein, when the target pressure value is reached, the processor holds the pressure at the target pressure value until the breathing patterns change from a current state to one of states (i) and (ii) and (iii).

4. The system according to claim 1, wherein the processor adjusts the pressure in predetermined increments to approach the target pressure value.

5. The system according to claim 2, wherein the therapeutic pressure adjustment arrangement controls the generator until the breathing patterns indicate state (iv).

6. The system according to claim 2, wherein the therapeutic pressure adjustment arrangement executes a self-titrating algorithm to control the pressure.

7. The system according to claim 1, wherein when the breathing patterns indicate a change from one of states (i), (ii), (iii) to the state (iv), the processing arrangement controls the generator to reduce the pressure.

8. The system according to claim 2, wherein when the breathing patterns indicate a change from state (iv) to one of states (i), (ii) and (iii), the processing arrangement transfers control of the generator to the therapeutic pressure adjustment arrangement which increases the pressure supplied by the generator.

9. A method for treatment of sleeping disorder in a patient using a positive airway pressure, comprising the steps of:

supplying an airflow to an airway of a patient using a flow generator;

measuring data corresponding to the patient'"'"'s breathing patterns;

analyzing with the processing arrangement the data corresponding to the breathing patterns to determine whether the breathing patterns are indicative of at least one of the following patient states;

(i) a regular breathing state, (ii) a sleep disorder breathing state, (iii) a REM sleep state, and (iv) a troubled wakefulness state;

using the processing arrangement, controlling the generator to adjust the supplied pressure as a function of the patient'"'"'s state; and

when the breathing patterns indicate state (iv), controlling the generator to adjust the supplied pressure to approach a target pressure value.

10. The method according to claim 9, further comprising:

when the breathing patterns indicate one of states (i) and (ii) and (iii), transferring control of the generator, by the processing arrangement, to a therapeutic pressure adjustment arrangement.

11. The method according to claim 9, further comprising:

when the target pressure value is reached, maintaining pressure at the target pressure value by the processing arrangement until the breathing patterns change from a current state to one of states (i) and (ii) and (iii).

12. The method according to claim 9, further comprising:

adjusting the pressure in predetermined increments to approach the target pressure value.

13. The method according to claim 10, further comprising:

controlling the generator by the therapeutic pressure adjustment arrangement until the breathing patterns indicate state (iv).

14. The method according to claim 13, wherein controlling step further includes the substep of:

executing a self-titrating algorithm by the therapeutic pressure adjustment arrangement.

15. The method according to claim 9, wherein, when the breathing patterns indicate a change from one of states (i), (ii), (iii) to the state (iv), reducing, by the processing arrangement, the pressure supplied by the generator.

16. The method according to claim 10, wherein, when the breathing patterns indicate a change from state (iv) to one of states (i), (ii) and (iii), increasing, by the therapeutic pressure adjustment arrangement, the pressure supplied by the generator.