Subretinal implantation device and surgical cannulas for use therewith
First Claim
1. An implantation device for implanting a solid or semisolid implant into a mammal or human, comprising:
- a reservoir for holding an implant and a carrier fluid, wherein said reservoir includes a cannula, said cannula having a tip end and a delivery opening therein both shaped and dimensioned so said device can implant an implant into the subretinal space of a mammalian or human eye, wherein an implant and carrier fluid can be expressed from said delivery opening into the subretinal space of the recipient eye, wherein the cannula is of sufficient length that the tip end can reach the subretinal space while the remainder of the fluid reservoir is external of the eye, wherein said tip end is bent to accommodate the shape of the back of the eye, wherein expression of the carrier fluid from the reservoir via said delivery opening expels the implant through said delivery opening.
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Accused Products
Abstract
An implantation device having a reservoir for holding a solid or semisolid implant and a carrier fluid, wherein the reservoir includes a cannula. The cannula has a tip end and a delivery opening therein both shaped and dimensioned to suit the application. For example, an implant (such as a retinal cell graft) and suitable carrier fluid (such as an aqueous hyaluronic acid solution) can be expressed from the opening into the subretinal space of a recipient eye, provided the cannula is of sufficient length that the tip end can reach the subretinal space while the remainder of the fluid reservoir is external of the eye. Expression of the carrier fluid from the reservoir via the delivery opening expels the implant through the delivery opening. An electromechanically driven plunger apparatus with operator controls is provided in a preferred embodiment.
76 Citations
20 Claims
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1. An implantation device for implanting a solid or semisolid implant into a mammal or human, comprising:
a reservoir for holding an implant and a carrier fluid, wherein said reservoir includes a cannula, said cannula having a tip end and a delivery opening therein both shaped and dimensioned so said device can implant an implant into the subretinal space of a mammalian or human eye, wherein an implant and carrier fluid can be expressed from said delivery opening into the subretinal space of the recipient eye, wherein the cannula is of sufficient length that the tip end can reach the subretinal space while the remainder of the fluid reservoir is external of the eye, wherein said tip end is bent to accommodate the shape of the back of the eye, wherein expression of the carrier fluid from the reservoir via said delivery opening expels the implant through said delivery opening. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 15, 16, 17, 18, 19, 20)
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14. An implantation device for implanting a solid or semisolid implant into a mammal or human eye, comprising:
a reservoir for holding an implant and a carrier fluid, said reservoir holding an implant comprising a retinal cell graft, wherein said reservoir includes a cannula, said cannula having a tip end and a delivery opening therein both shaped and dimensioned so said device can implant said implant into the subretinal space of a mammalian or human eye, wherein said implant and carrier fluid can be expressed from said delivery opening into the subretinal space of the recipient eye, wherein the cannula is of sufficient length that the tip end can reach the subretinal space while the remainder of the fluid reservoir is external of the eye, wherein expression of the carrier fluid from the reservoir via said delivery opening expels said implant through said delivery opening.
Specification