Method and device for patient temperature control employing optimized rewarming

• US 7,189,254 B2
• Filed: 08/24/2004
• Issued: 03/13/2007
• Est. Priority Date: 02/09/1999
• Status: Expired due to Term

• Current Assignee: Zoll Circulation Incorporated (Asahi Kasei Corporation)
• Original Assignee: Innercool therapies Incorporated (Taxus Cardium Pharmaceuticals Group, Inc.)
• Inventors: Magers, Michael
• Primary Examiner(s): GIBSON, ROY DEAN
• Application Number:
  US10/925,043
• Publication Number:
  US 20050131502A1
• Time in Patent Office: 931 Days
• Field of Search: 607/96, 607104-106, 607/113
• US Class Current: 607/105
• CPC Class Codes: A61B 18/02 by cooling, e.g. cryogenic techniques devices for cooling specific reflex points of the body within cell-life limits A61H39/06
• CPC Class Codes: A61B 2017/00292 mounted on or guided by flexible, e.g. catheter-like, means
• CPC Class Codes: A61B 2018/0212 using an instrument inserted into a body lumen, e.g. catheter
• CPC Class Codes: A61B 2018/0262 using a circulating cryogenic fluid
• CPC Class Codes: A61F 2007/0056 for cooling
• CPC Class Codes: A61F 2007/0288 during operations
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities
• CPC Class Codes: A61F 7/123 using a flexible balloon containing the thermal element
• CPC Class Codes: A61M 2025/0004 having two or more concentrically arranged tubes for forming a concentric catheter system
• CPC Class Codes: A61M 2025/006 having a special surface topography or special surface properties, e.g. roughened or knurled surface
• CPC Class Codes: A61M 2205/3606 cooled
• CPC Class Codes: A61M 25/00 Catheters; Hollow probes dilators A61M29/00; peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00 ; for measuring or testing A61B; materials for catheters A61L29/00
• CPC Class Codes: A61M 25/0023 by the form of the lumen, e.g. cross-section, variable diameter

Abstract

Embodiments of the invention provide a system for temperature control of the human body. The system includes an indwelling catheter with a tip-mounted heat transfer element. The catheter is fluidically coupled to a console that provides a heated or cooled heat transfer working fluid to exchange heat with the heat transfer element, thereby heating or cooling blood. The heated or cooled blood then heats or cools the patient'"'"'s body or a selected portion thereof. In particular, strategies for optimizing the rewarming of patients for various medical procedures are provided, including stroke, neurosurgery, and myocardial infarction.

Claims

1. A method of rewarming a patient following neurosurgery, comprising:

draping a patient with a blanket;

inserting a heat transfer element into a vein of the patient;

circulating a working fluid through the heat transfer element, the working fluid heated by a heat exchanger to a temperature sufficient to raise the temperature of a blood stream to a temperature less than about 42°

C.;

sensing a patient temperature;

controlling the patient xempcrature to a target temperature of about between about 35°

C. and 36°

C.; and

rewarming the patient to normoxhennia using an active heating blanket,

wherein the heat transfer element includes at least two heat transfer segments having alternating helical rotations.

2. The method of claim 1, wherein the heat transfer element is flexible and is made of metal.

3. The method of claim 2, wherein the at least two heat transfer segments are separated by bellows.

4. The method of claim 1, wherein the heat transfer element is a balloon.

5. The method of claim 1, wherein the sensing a patient temperature includes sensing a patient temperature with an esophageal probe.

6. A method of rewarming a patient following a stroke, comprising:

covering a patient with a heating blanket set to a temperature of between about 38°

C. and 43°

C.;

inserting a heat transfer element into a vein of the patient;

circulating a working fluid through the heat transfer element;

sensing a patient temperature;

controlling the patient temperature such that the patient temperature rises from less than about 33°

C. to greater than about 36°

C. over a period of time between about 6 hours to about 24 hours;

if the patient is experiencing shivering during the controlled rewarm, administering an antishivering drug; and

rewarming the patient to normotherinia using the active heating blanket,

wherein the heat transfer element includes at least two heat transfer segments having alternating helical rotations.

7. The method of claim 6, wherein the heat transfer element is flexible and is made of metal.

8. The method of claim 7, wherein the at least two heat transfer segments are separated by bellows.

9. The method of claim 6, wherein the heat transfer element is a balloon.

10. The method of claim 6, wherein the sensing a patient temperature includes sensing a patient temperature with an esophageal probe.

11. The method of claim 6, wherein the sensing a patient temperature includes sensing a patient temperature with a bladder probe.

12. A method of rewarming a patient following a stroke, comprising:

covering a patient with a heating blanket set to a temperature of between about 38°

C. and 43°

C.

inserting a heat transfer element into a vein of the patient;

circulating a workinig fluid through the heat transfer element;

sensing a patient temperature;

controlling the patient temperature such that the patient temperature rises from less than about 33°

C. to greater than about 36°

C. over a period of time between about 6 hours to about 24 hours;

if the patient is experiencing shivering during the controlled rewarm, administering an antishivering drug; and

rewarming the patient to normothennia using the activc heating blanket, wherein the anti-shivering drug is meperidine.