Electrical detection of selected species
First Claim
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1. A biosensor system for the detection of biological target molecules comprising:
- a biosensor device, including;
one or more organic field effect transistors each of said transistors including a channel comprising;
a semiconductive film comprising organic molecules; and
probe molecules capable of binding to target molecules coupled to an outer surface of said semiconductive film, said semiconductive film having an interior substantially free of said probe moleculeswherein said organic molecules are hydrophobic and said probe molecules are hydrophilic;
a sample capable of holding said target molecules; and
an assay system configured to bring said biosensor device in contact with said sample.
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Abstract
The present invention provides an organic field effect transistor and a method of fabricating the transistor. The transistor includes a semiconductive film comprising organic molecules. Probe molecules capable of binding to target molecules are coupled to an outer surface of the semiconductive film such that the interior of the film being substantially free of the probe molecules.
11 Citations
15 Claims
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1. A biosensor system for the detection of biological target molecules comprising:
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a biosensor device, including; one or more organic field effect transistors each of said transistors including a channel comprising; a semiconductive film comprising organic molecules; and
probe molecules capable of binding to target molecules coupled to an outer surface of said semiconductive film, said semiconductive film having an interior substantially free of said probe moleculeswherein said organic molecules are hydrophobic and said probe molecules are hydrophilic; a sample capable of holding said target molecules; and an assay system configured to bring said biosensor device in contact with said sample. - View Dependent Claims (2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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4. An organic field effect transistor for the detection of biological target molecules comprising:
a transistor channel having a semiconductive film comprising organic molecules and probe molecules coupled to an outer surface of said semiconductive film, said film having an interior substantially free of said probe molecules wherein said organic molecules are hydrophobic and said probe molecules are hydrophilic.
Specification