Targeted stent placement and multi-stent therapy

• US 7,192,412 B1
• Filed: 09/15/2003
• Issued: 03/20/2007
• Est. Priority Date: 09/14/2002
• Status: Active Grant

• Current Assignee: Glaukos Corporation
• Original Assignee: Glaukos Corporation
• Inventors: Zhou, Jianbo, Smedley, Gregory
• Primary Examiner(s): Hindenburg; Max F.
• Assistant Examiner(s): Apanius; Michael
• Application Number:
  US10/662,696
• Time in Patent Office: 1,282 Days
• Field of Search: 600/398, 600/399, 604 8- 10, 604/521, 623/4.1, 623/905, 606/108
• US Class Current: 604/8
• CPC Class Codes: A61B 2034/101 Computer-aided simulation of surgical operations
• CPC Class Codes: A61B 2034/104 Modelling the effect of the tool, e.g. the effect of an implanted prosthesis or for predicting the effect of ablation or burring
• CPC Class Codes: A61B 2034/105 Modelling of the patient, e.g. for ligaments or bones
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

A trabecular flow model for producing treatment recommendations for patients with elevated intraocular pressure is disclosed. One method includes providing intraocular pressure measurements for a patient; providing aqueous cavity information, such as collector channel resistance and Schlemm'"'"'s canal resistance, and determining a treatment recommendation for the patient based on the aforementioned parameters.

Claims

1. A method of treating a patient with elevated intraocular pressure using a treatment recommendation which provides at least one of a recommended location of a stent implantation and a recommended number of stents to be implanted, the method comprising:

acquiring a treatment recommendation comprising said at least one of said recommended location of said stent implantation and said recommended number of stents to be implanted for the patient, the treatment recommendation based on a baseline intraocular pressure of the patient, at least one of a target intraocular pressure and a target reduction in intraocular pressure for the patient, and at least one aqueous cavity datum, wherein the at least one aqueous cavity datum is selected from the group of a collector channel resistance, a Schlemm'"'"'s canal resistance, a length of a segment of Schlemm'"'"'s canal, a height of Schlemm'"'"'s canal, and a width of Schlemm'"'"'s canal; and

treating the patient according to the treatment recommendation.

2. The method of claim 1, wherein the recommended location of a stent implantation comprises a distance from a collector channel.

3. The method of claim 2, wherein the distance is measured along Schlemm'"'"'s canal.

4. The method of claim 1,

wherein the treatment recommendation is also based on at least one additional ocular datum, the at least one additional ocular datum selected from the group of an episcleral venous pressure, a trabecular meshwork resistance, a facility of outflow, and a viscosity of aqueous humor.

5. The method of claim 1, wherein the treating comprises implanting one or more stents to reduce the elevated intraocular pressure.

6. A method of treating a patient with elevated intraocular pressure using a treatment recommendation, the method comprising:

acquiring a treatment recommendation comprising at least one of a recommended location of a stent implantation and a recommended number of stents to be implanted for the patient, the treatment recommendation based on a baseline intraocular pressure of the patient, at least one of a target intraocular pressure and a target reduction in intraocular pressure for the patient, and at least one of a location of at least one collector channel and a distribution of a plurality of collector channels; and

treating the patient according to the treatment recommendation.

7. The method of claim 6, wherein the recommended location of a stent implantation is selected from the group consisting of nasal, temporal, a quadrantic position, and a clock-hour position.

8. The method of claim 6, wherein the distribution of a plurality of collector channels is determined by imaging the patient.

9. The method of claim 6, wherein the distribution of a plurality of collector channels is determined at least in part from statistical data from eyes other than the patient'"'"'s eyes.

10. The method of claim 6, wherein the treating comprises implanting one or more stents to reduce the elevated intraocular pressure.