Method and device for treatment of mitral insufficiency
First Claim
1. A device for treatment of mitral annulus dilatation, comprising an elongate body having such dimensions as to be insertable into the coronary sinus and having two states, in a first of which the elongate body has a shape that is adaptable to the shape of the coronary sinus, and to the second of which the elongate body is transferable from said first state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus is reduced as well as the circumference of the mitral valve annulus, when the elongate body is positioned in the coronary sinus, said elongate body comprising at least one stent section at a distance from each end of the elongate body, said at least one stent section providing a reduction of its length when expanded in situ in the coronary sinus, whereby the elongate body is shortened and bent to a smaller radius of curvature, wherein the at least one stent section is a central stent section of the elongate body, the central stent section located between a distal stent section and a proximal stent section of the elongate body, the distal and proximal stent sections being expandable prior to the central stent section.
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Accused Products
Abstract
A device for treatment of mitral annulus dilatation comprises an elongate body having two states. In a first of these states the elongate body is insertable into the coronary sinus and has a shape adapting to the shape of the coronary sinus. When positioned in the coronary sinus, the elongate body is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced.
145 Citations
21 Claims
- 1. A device for treatment of mitral annulus dilatation, comprising an elongate body having such dimensions as to be insertable into the coronary sinus and having two states, in a first of which the elongate body has a shape that is adaptable to the shape of the coronary sinus, and to the second of which the elongate body is transferable from said first state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus is reduced as well as the circumference of the mitral valve annulus, when the elongate body is positioned in the coronary sinus, said elongate body comprising at least one stent section at a distance from each end of the elongate body, said at least one stent section providing a reduction of its length when expanded in situ in the coronary sinus, whereby the elongate body is shortened and bent to a smaller radius of curvature, wherein the at least one stent section is a central stent section of the elongate body, the central stent section located between a distal stent section and a proximal stent section of the elongate body, the distal and proximal stent sections being expandable prior to the central stent section.
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4. A medical device for remodeling an extravascular tissue structure adjacent to a vessel in a patient, comprising:
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an elongate body adapted to be fixed to the vessel, the elongate body extending between a proximal end and a distal end, and that is adjustable from a first configuration having a first shape such that the elongate body is adapted to be delivered at least in part into the vessel to a second configuration having a second shape such that the elongate body is adapted to be fixed to the vessel, and to a third configuration having a third shape such that the elongate body is adapted to exert a force from within the vessel onto the extravascular tissue structure in order to remodel the extravascular tissue structure, and wherein the elongate body is adapted to be positioned in the first configuration at least in part within a coronary sinus and is adapted to remodel a mitral valve annulus adjacent to the coronary sinus after it is fixed to the coronary sinus; wherein the distal end of the elongate body is spaced distally from the proximal end of the elongate body in the first and third configurations; wherein, in at least one of the second configuration and the third configuration, the proximal and distal ends of the elongate body have a greater cross-sectional profile than a central section of the elongate body. - View Dependent Claims (5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 16, 17, 18)
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15. A medical system for remodeling an extravascular tissue structure adjacent to a vessel in a patient, comprising:
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an elongate body adapted to be fixed to the vessel, the elongate body extending between a proximal end and a distal end, and that is adjustable from a first configuration having a first shape such that the elongate body is adapted to be delivered at least in part into the vessel to a second configuration having a second shape such that the elongate body is adapted to be fixed to the vessel, and to a third configuration having a third shape such that the elongate body is adapted to exert a force from within the vessel onto the extravascular tissue structure in order to remodel the extravascular tissue structure, wherein the elongate body is adapted to be positioned in the first configuration at least in part within the coronary sinus and is adapted to remodel a mitral valve annulus adjacent to the coronary sinus after it is fixed to the coronary sinus, and a deployment system cooperating with the elongate body and which is adapted to at least in part deliver the elongate body in the first configuration at least in part into the coronary sinus; wherein the distal end of the elongate body is spaced distally from the proximal end of the elongate body in the first and third configurations; wherein, in at least one of the second configuration and the third configuration, the proximal and distal ends of the elongate body have a greater cross-sectional profile than a central section of the elongate body. - View Dependent Claims (19, 21)
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20. A medical device for remodeling a tissue structure adjacent to a body space that is defined at least in part by a tissue wall in a patient, comprising:
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an elongate body adapted to be fixed to the body space, the elongate body extending between a proximal end portion and a distal end portion and that is adjustable from a first configuration having a first shape that is adapted to be delivered at least in part into the body space to a second configuration having a second shape that is adapted to be fixed to the vessel, and to a third configuration having a third shape such that the elongate body is adapted at least in part to exert a force from within the body space onto the adjacent tissue structure in order to remodel the adjacent tissue structure, wherein the elongate body is adapted to be positioned in the first configuration at least in part within a coronary sinus and is adapted to remodel a mitral valve annulus adjacent to the coronary sinus after it is fixed to the coronary sinus; wherein the distal end of the elongate body is spaced distally from the proximal end of the elongate body in the first and third configurations; wherein, in at least one of the second configuration and the third configuration, the proximal and distal ends of the elongate body have a greater cross-sectional profile than a central section of the elongate body.
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Specification