Human semaphorin homologs and polynucleotides encoding the same

• US 7,199,221 B2
• Filed: 04/28/2004
• Issued: 04/03/2007
• Est. Priority Date: 05/18/2000
• Status: Expired due to Fees

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Walke, D. Wade, Turner, C. Alexander Jr., Wang, Xiaoming, Scoville, John
• Primary Examiner(s): Andres; Janet L.
• Assistant Examiner(s): Gucker; Stephen
• Application Number:
  US10/833,509
• Publication Number:
  US 20050054040A1
• Time in Patent Office: 1,070 Days
• Field of Search: None
• US Class Current: 530/350
• CPC Class Codes: C07K 14/4703 Inhibitors; Suppressors

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims

1. An isolated nucleic acid molecule comprising at a nucleotide sequence encoding an amino acid sequence drawn from the group consisting of SEQ ID NOS:

2, 4, 6, 8, 10, 12, 14, 16, 19, 21, 23, 25, 27, 29, 31, 33, 35, 37, 39, 41, 43, 45, 47, and 49.

2. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

4; and

(b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO;

3 or the complement thereof.

3. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

4.

4. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

2.

5. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

12.

6. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

29; and

(b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO;

28 or the complement thereof.

7. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

29.

8. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

33.

9. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

25.

10. A purified polypeptide comprising the amino acid sequence of SEQ ID NO:

2.