Anisotropic nanoparticle amplification of magnetic resonance signals
First Claim
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1. A method for amplifying generated or detected alternating magnetic flux of an induction coil in the presence of a large DC magnetic field, the method comprising steps of:
- disposing nanoparticles having substantially uniaxial or unidirectional magnetic anisotropy in combination with a reversible transverse susceptibility at the level of the large DC magnetic field within the induction coil and with their nanoparticle magnetic easy axes substantially commonly aligned at an angle relative to the large DC magnetic field; and
establishing an alternating current within the induction coil whereby a magnetic flux signal that is generated or detected by the induction coil is amplified by the presence of the nanoparticles within the induction coil.
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Abstract
The reversible transverse susceptibility of magnetic nanoparticles is used to achieve magnetic flux amplification in magnetic resonance settings. Nanoparticles having substantially uniaxial or unidirectional magnetic anisotropy and a reversible transverse susceptibility in the presence of the high DC magnetic field provide either or both of an amplification of the generated signal of an inductive coil or the detected signal of an inductive coil.
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Citations
13 Claims
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1. A method for amplifying generated or detected alternating magnetic flux of an induction coil in the presence of a large DC magnetic field, the method comprising steps of:
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disposing nanoparticles having substantially uniaxial or unidirectional magnetic anisotropy in combination with a reversible transverse susceptibility at the level of the large DC magnetic field within the induction coil and with their nanoparticle magnetic easy axes substantially commonly aligned at an angle relative to the large DC magnetic field; and establishing an alternating current within the induction coil whereby a magnetic flux signal that is generated or detected by the induction coil is amplified by the presence of the nanoparticles within the induction coil. - View Dependent Claims (2, 3, 4, 5, 6)
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- 7. In a magnetic resonance system having alternating current generation and detection in inductive coils disposed in the presence of a magnetic resonance DC bias field, an improvement comprising nanoparticles having substantially uniaxial or unidirectional magnetic anisotropy in combination with a reversible transverse susceptibility at the level of the magnetic resonance DC bias field, the nanoparticles being disposed within the core of at least one of the inductive coils and positioned relative to the DC bias field in order to amplify magnetic flux in the at least one of the inductive coils.
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12. A magnetic resonance system, the system comprising:
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DC magnetic generation means for generating a polarizing DC magnetic field; and inductive coil means for generating excitation time-dependent magnetic fields perpendicularly to the DC magnetic field and for detecting weak time-dependent sample generated magnetic fields;
said inductive coil means including nanoparticle amplification means for amplifying at least one of the excitation time-dependent magnetic fields and the weak time-dependent sample generated magnetic fields. - View Dependent Claims (13)
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Specification