Water-soluble or water-swellable crosslinked copolymers

• US 7,208,556 B2
• Filed: 03/17/2005
• Issued: 04/24/2007
• Est. Priority Date: 01/11/2000
• Status: Expired due to Fees

• Current Assignee: Clariant Produkte AG (Clariant AG)
• Original Assignee: Clariant Produkte AG (Clariant AG)
• Inventors: Loffler, Matthias, Morschhauser, Roman
• Primary Examiner(s): Lipman; Bernard
• Application Number:
  US11/082,333
• Publication Number:
  US 20050165188A1
• Time in Patent Office: 768 Days
• Field of Search: 526/264
• US Class Current: 526/264
• CPC Class Codes: A61K 47/32 Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers , poly(meth)acrylates, or polyvinyl pyrrolidone
• CPC Class Codes: A61K 8/8182 Copolymers of vinyl-pyrrolidones. Compositions of derivatives of such polymers
• CPC Class Codes: A61K 9/0014 Skin, i.e. galenical aspects of topical compositions non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: C08F 220/585 and containing other heteroatoms, e.g. 2-acrylamido-2-methylpropane sulfonic acid [AMPS]

Abstract

Water-soluble or water-swellable crosslinked copolymers consisting essentially of structural units of the formula 1

or a mixture of the structural units of the formula 1 with structural units of the formula 2

and structural units of the formula 3

where R, R¹, R², R³, Z and n are as defined in the description. These copolymers are crosslinked with compounds which contain at least two olefinic double bonds. These crosslinked copolymers are suitable as thickeners, in particular for cosmetic and pharmaceutical preparations.

Claims

1. A water-soluble or water-swellable crosslinked copolymer consisting essentially of

a1) 1 to 50% by weight of a repeating structural unit of formula (1)

2. The copolymer as claimed in claim 1, consisting essentially of 2 to 30% by weight of component a1) or mixture a2), 69.5 to 97.5% by weight of component b) and 0.2 to 3% by weight of component c).

3. The copolymer as claimed in claim 1, consisting essentially of 3 to 15% by weight of component a1) or mixture a2), 84.5 to 96.5% by weight of component b) and 0.5 to 2% by weight of component c).

4. The copolymer as claimed in claim 1, wherein the monomer of component c) is allyl (meth)acrylate.

5. A cosmetic preparation or a pharmaceutical preparation comprising the water-soluble or water-swellable crosslinked copolymer of claim 1.

6. The water-soluble or water-swellable crosslinked copolymer of claim 1 wherein R, R¹ and R² are a linear or branched alkyl or alkenyl group having in each case 1 to 20 carbon atoms.

7. The water-soluble or water-swellable crosslinked copolymer of claim 1 wherein R, R¹ and R² are a linear or branched alkyl or alkenyl group having in each case 1 to 12 carbon atoms.

9. The water-soluble or water-sellable crosslinked copolymer of claim 1, wherein in component c) the monomer is selected from the group consisting of allyl acrylate, allyl methacrylate, allyl ethyl methacrylate, trimethylolpropane trimethacrylate, trimethylolpropane triacrylate, dipropylene glycol diallyl ether, polyglycol diallyl ether, triethylene glycol divinyl ether, hydroquinone diallyl ether, tetraallyloxyethane, tetraethylene glycol diacrylate, triallylamine, trimethylolpropane diallyl ether, methylene bisacrylamide, divinylbenzene, and mixtures thereof.

8. A water-soluble or water-swellable crosslinked copolymer consisting essentially of

a) 1 to 50% by weight of a mixture of a structural unit of formula (1)

10. The water-soluble or water-swellable crosslinked copolymer of claim 8, wherein in component c) the monomers are selected from the group consisting of allyl acrylate, allyl methacrylate, allyl ethyl methacrylate, trimethylolpropane trimethacrylate, trimethylolpropane triacrylate, dipropylene glycol diallyl ether, polyglycol diallyl ether, triethylene glycol divinyl ether, hydroquinone diallyl ether, tetraallyloxyethane, tetraethylene glycol diacrylate, triallylamine, trimethylolpropane diallyl ether, methylene bisacrylamide, divinylbenzene, and mixtures thereof.

11. A cosmetic preparation or a pharmaceutical preparation comprising the water-soluble or water swellable crosslinked copolymer of claim 8.