Methods and apparatuses for arrhythmia detection and classification using wireless ECG

• US 7,212,849 B2
• Filed: 10/28/2004
• Issued: 05/01/2007
• Est. Priority Date: 10/28/2004
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: McCabe, Aaron, Zhang, Yi, Thompson, Julie, Yonce, David J.
• Primary Examiner(s): Pezzuto; Robert
• Assistant Examiner(s): LEE, YUN H
• Application Number:
  US10/975,166
• Publication Number:
  US 20060095083A1
• Time in Patent Office: 915 Days
• Field of Search: 600/509, 600/515, 600/518, 607/5, 607/14, 607/18
• US Class Current: 600/515
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/353 Detecting P-waves
• CPC Class Codes: A61B 5/686 Permanently implanted devices, e.g. pacemakers, other stimulators, biochips A61B5/6861 takes precedence
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/3706 Pacemaker parameters stimulation threshold A61N1/371
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators
• CPC Class Codes: A61N 1/3925 Monitoring; Protecting
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion

Abstract

A CRM system enhances intracardiac electrogram-based arrhythmia detection using a wireless electrocardiogram (ECG), which is a signal sensed with implantable electrodes and approximating a surface ECG. In one embodiment, an intracardiac electrogram allows for detection of an arrhythmia, and the wireless ECG allows for classification of the detected arrhythmia by locating its origin. In another embodiment, the wireless ECG is sensed as a substitute signal for the intracardiac electrogram when the sensing of the intracardiac electrogram becomes unreliable. In another embodiment, a cardiac signal needed for a particular purpose is selected from one or more intracardiac electrograms and one or more wireless ECGs based on a desirable signal quality. In another embodiment, intracardiac electrogram-based arrhythmia detection and wireless ECG-based arrhythmia detection confirm with each other before indicating a detection of arrhythmia of a certain type.

Claims

1. A cardiac rhythm management (CRM) system, comprising:

an implantable medical device including;

an electrogram sensing circuit to sense an intracardiac electrogram;

a wireless electrocardiogram (ECG) sensing circuit to sense a subcutaneous ECG;

a first arrhythmia detection circuit, coupled to the electrogram sensing circuit, to detect an arrhythmia based on the intracardiac electrogram; and

an arrhythmia classification circuit, coupled to the wireless ECG sensing circuit and the arrhythmia detection circuit, to classify the detected arrhythmia based on at least the subcutaneous ECG; and

a plurality of implantable subcutaneous electrodes coupled to the wireless ECG sensing circuit.

2. The system of claim 1, wherein the plurality of implantable subcutaneous electrodes comprises at least one electrode incorporated onto the implantable medical device.

3. The system of claim 1, further comprising a ventricular lead coupled to the electrogram sensing circuit, the ventricular lead including one or more ventricular electrodes for sensing a ventricular electrogram, and wherein the first arrhythmia detection circuit comprises a ventricular arrhythmia detector.

4. The system of claim 3, wherein the ventricular arrhythmia detector comprises one or more of a ventricular tachycardia detector and a ventricular fibrillation detector.

5. The system of claim 4, wherein the implantable medical device further comprises a cardioversion/defibrillation circuit, coupled to the arrhythmia classification circuit, to deliver a cardioversion/defibrillation shock when the detected arrhythmia is classified as at least one of a ventricular tachycardia and a ventricular fibrillation.

6. The system of claim 5, wherein the implantable medical device further comprises an anti-tachycardia pacing (ATP) circuit, coupled to the arrhythmia classification circuit, to deliver ATP pulses when the detected arrhythmia is classified as a ventricular tachycardia.

7. The system of claim 3, wherein the implantable medical device further comprises:

a ventricular event detector, coupled to the electrogram sensing circuit, to detect ventricular events from the ventricular electrogram;

a ventricular rate detector, coupled to the ventricular event detector, to detect a ventricular rate;

an atrial event detector, coupled to the wireless ECG sensing circuit, to detect atrial events from the subcutaneous ECG; and

an atrial rate detector, coupled to the atrial event detector, to detect an atrial rate,

wherein the arrhythmia classification circuit comprises a rate comparator including a first input to receive the atrial rate, a second input to receive the ventricular rate, and an output indicative of an arrhythmia type classified based on a comparison between the atrial rate and the ventricular rate.

8. The system of claim 3, wherein the implantable medical device farther comprises a second arrhythmia detection circuit including an atrial arrhythmia detector, and wherein the arrhythmia classification circuit comprises a specificity enhancement circuit adapted to classify the detected arrhythmia based on at least whether an atrial arrhythmia is detected.

9. The system of claim 8, wherein the atrial arrhythmia detector comprises one or more of an atrial tachycardia detector and an atrial fibrillation detector, and the specificity enhancement circuit is adapted to classify the detected arrhythmia based on at least whether at least one of an atrial tachycardia and an atrial fibrillation is detected.

10. The system of claim 3, wherein the plurality of implantable electrodes comprises a plurality of subcutaneous electrodes incorporated onto the implantable medical device and configured for sensing atrial depolarizations.

11. A cardiac rhythm management (CRM) system, comprising:

an implantable medical device having a circuit including;

an electrogram sensing circuit to sense an intracardiac electrogram;

a wireless electrocardiogram (ECG) sensing circuit to sense a subcutaneous ECG;

a first arrhythmia detection circuit, coupled to the electrogram sensing circuit, to detect an arrhythmia based on the intracardiac electrogram;

an arrhythmia classification circuit, coupled to the wireless ECG sensing circuit and the arrhythmia detection circuit, to classify the detected arrhythmia based on at least the subcutaneous ECG; and

a hermetically sealed can to house the circuit of the implantable medical device; and

a plurality of implantable subcutaneous electrodes coupled to the wireless ECG sensing circuit and including a can electrode including at least a conductive portion of the hermetically sealed can.

12. The system of claim 11, wherein the implantable medical device comprises a header attached to the hermetically sealed can, and wherein the plurality of implantable subcutaneous electrodes comprise one or more header electrodes incorporated into the header.

13. The system of claim 11, wherein the implantable medical device further comprises an antenna electrically connected to the circuit of the implantable medical device for telemetry, and wherein the plurality of implantable subcutaneous electrodes comprise an antenna electrode including a portion of the antenna.

14. The system of claim 11, wherein the implantable medical device comprises:

a ventricular event detector, coupled to the electrogram sensing circuit, to detect ventricular events from the intracardiac electrogram; and

a ventricular rate detector, coupled to the ventricular event detector, to detect a ventricular rate,

and wherein the first arrhythmia detection circuit comprises a ventricular arrhythmia detector to detect a ventricular arrhythmia by comparing the ventricular rate to a first predetermined tachycardia threshold rate.

15. The system of claim 14, wherein the implantable medical device comprises:

an atrial event detector, coupled to the wireless ECG sensing circuit, to detect atrial events from the subcutaneous ECG; and

an atrial rate detector, coupled to the atrial event detector, to detect an atrial rate.

16. The system of claim 15, wherein the arrhythmia classification circuit comprises a rate comparator including a first input to receive the atrial rate, a second input to receive the ventricular rate, and an output indicative of an arrhythmia type classified based on a comparison between the atrial rate and the ventricular rate.

17. The system of claim 16, wherein the implantable medical device further comprises a second arrhythmia detection circuit including an atrial arrhythmia detector to detect an atrial arrhythmia by comparing the atrial rate to a second predetermined tachycardia threshold rate, and wherein the arrhythmia classification circuit is adapted to classify the detected arrhythmia based on at least whether the atrial arrhythmia is detected.

18. A cardiac rhythm management (CRM) system, comprising:

an implantable medical device having a circuit including;

an electrogram sensing circuit to sense an intracardiac electrogram;

a wireless electrocardiogram (ECG) sensing circuit to sense a subcutaneous ECG;

a first arrhythmia detection circuit, coupled to the electrogram sensing circuit, to detect an arrhythmia based on the intracardiac electrogram;

an arrhythmia classification circuit, coupled to the wireless ECG sensing circuit and the arrhythmia detection circuit, to classify the detected arrhythmia based on at least the subcutaneous ECG;

a hermetically sealed can to house the circuit of the implantable medical device; and

a header attached to the hermetically sealed can; and

a plurality of implantable subcutaneous electrodes coupled to the wireless ECG sensing circuit and including one or more header electrodes incorporated into the header.

19. The system of claim 18, wherein the implantable medical device further comprises an antenna electrically connected to the circuit of the implantable medical device for telemetry, and wherein the plurality of implantable subcutaneous electrodes comprise an antenna electrode including a portion of the antenna.

20. The system of claim 18, wherein the implantable medical device comprises:

an atrial event detector, coupled to the wireless ECG sensing circuit, to detect atrial events from the subcutaneous ECG; and

an atrial rate detector, coupled to the atrial event detector, to detect an atrial rate.