System and method for adaptive drug delivery
First Claim
1. A medication delivery controller for controlling the administration of medication to a patient to achieve and maintain a target effect in said patient, the controller comprising:
- a sensor interface configured to receive one or more patient parameters from a sensor package, said parameters quantifying the patient'"'"'s response to the level of medication,a processor coupled to said sensor interface configured;
(a) to compute a first patient response profile, said first patient response profile indicating the patient'"'"'s individualized response to said medication;
(b) to determine from said first patient response profile a first concentration level of said medication to maintain said target effect in said patient;
(c) to determine whether the patient'"'"'s response to said first concentration level of said medication has changed and, when the patient'"'"'s response to said first concentration level has changed, to compute a second patient response profile reflecting the patient'"'"'s new individualized response to said medication and(d) to determine from said second patient response profile a new concentration level of medication to maintain said target effect in said patient; and
a data output port coupled to said processor to forward instructions to a medication delivery unit to deliver said medication at said medication delivery rate determined by said processor, wherein said one or more parameters indicate at least one of the group of blood pressure, heart rate, temperature, and EEG parameters.
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Accused Products
Abstract
A system and method for controlling the administration of medication to a patient utilizes adaptive feedback to achieve and maintain a target effect in said patient. A sensor package having one or more sensors is used to sense an attribute of the patient and to provide a parameter indicating the attribute being sensed. A medication delivery controller accepts one or more parameters from the sensor package and uses these parameters to determine the effect of a medication on a patient and the concentration level of medication that will achieve a desired effect. The medication delivery controller controls the medication delivery unit to deliver the medication at a rate determined to achieve said target concentration level of said medication in said patient. If the patient'"'"'s response to a given medication changes as a result of external stimuli, the medication delivery controller can detect this change and determine a new concentration level of medication which will achieve the desired effect. The medication delivery controller can steer the medication delivery unit to administer an amount of medication to reach this new concentration level.
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Citations
12 Claims
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1. A medication delivery controller for controlling the administration of medication to a patient to achieve and maintain a target effect in said patient, the controller comprising:
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a sensor interface configured to receive one or more patient parameters from a sensor package, said parameters quantifying the patient'"'"'s response to the level of medication, a processor coupled to said sensor interface configured; (a) to compute a first patient response profile, said first patient response profile indicating the patient'"'"'s individualized response to said medication; (b) to determine from said first patient response profile a first concentration level of said medication to maintain said target effect in said patient; (c) to determine whether the patient'"'"'s response to said first concentration level of said medication has changed and, when the patient'"'"'s response to said first concentration level has changed, to compute a second patient response profile reflecting the patient'"'"'s new individualized response to said medication and (d) to determine from said second patient response profile a new concentration level of medication to maintain said target effect in said patient; and a data output port coupled to said processor to forward instructions to a medication delivery unit to deliver said medication at said medication delivery rate determined by said processor, wherein said one or more parameters indicate at least one of the group of blood pressure, heart rate, temperature, and EEG parameters. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A medication delivery controller for controlling the administration of medication to a patient to achieve and maintain a target effect in said patient, the controller comprising:
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a sensor interface configured to receive one or more patient parameters from a sensor package, said parameters quantifying the patient'"'"'s response to the level of medication, a processor coupled to said sensor interface configured; to compute a first patient response profile, said first patient response profile indicating the patient'"'"'s individualized response to said medication; to determine from said first patient response profile a first concentration level of said medication to maintain said taraet effect in said patient; (c) to determine whether the patient'"'"'s response to said first concentration level of said medication has changed and, when the patient'"'"'s response to said first concentration level has changed, to compute a second patient response profile reflecting the patient'"'"'s new individualized response to said medication and (d) to determine from said second patient response profile a new concentration level of medication to maintain said target effect in said patient; and a data output port coupled to said processor to forward instructions to a medication delivery unit to deliver said medication at said medication delivery rate determined by said processor, wherein said concentration of medication in said patient is an effect-site concentration.
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8. A method of using a medication delivery controller for controlling the administration of medication to a patient to achieve and maintain a target effect in said patient, the method comprising:
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receiving one or more patient parameters from a sensor package, the parameters indicating one or more attributes sensed from the patient; determining a target concentration level of said medication to achieve said target effect based on said one or more received parameters; determining a medication delivery rate to achieve said target concentration level of said medication in said patient; and
instructing a medication delivery unit to deliver said medication at said medication delivery rate determined by said processor, wherein said one or more patient parameters indicate at least one of the group of blood pressure, heart rate, temperature, and EEG parameters. - View Dependent Claims (9)
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10. A method of using a medication delivery controller for controlling the administration of medication to a patient to achieve and maintain a target effect in said patient, the method comprising:
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receiving one or more patient parameters from a sensor package, the parameters indicating one or more attributes sensed from the patient; determining a target concentration level of said medication to achieve said target effect based on said one or more received parameters; determining a medication delivery rate to achieve said target concentration level of said medication in said patient; and instructing a medication delivery unit to deliver said medication at said medication delivery rate determined by said processor, wherein said method further comprises calculating a patient response profile and using said patient response profile to determine said target concentration level. - View Dependent Claims (11, 12)
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Specification