Implantable biosensor and methods for monitoring cardiac health
First Claim
1. A method of monitoring a concentration of suspended particles in a biomedical colloid comprising:
- a. producing an assaulting acoustic field;
b. measuring a resultant electric field produced in vivo by particle interaction with the assaulting field; and
c. determining the concentration of the suspended particles based on the measured resultant field.
1 Assignment
0 Petitions
Accused Products
Abstract
The ability to continuously monitor concentrations of any of a plurality of blood-borne substances, such as proteins, improves patient monitoring and overall care through early detection of cardiac threats. Ultrasound-based technology used in analytical chemistry to determine amounts of particles suspended in a colloidal composition can be employed in an implantable sensor to monitor levels of many different substances in the blood. A sensor system is implanted in or near a blood vessel in the body and generates an electric or acoustic field directed at that blood vessel. A receiver near the generator detects energy emitted once the assaulting field is turned off. Changes in the relative amounts of the substance(s) being monitored appear as changes in the amount of energy emitted once the assaulting field is removed. The sensor may be implemented in an implantable cardiac therapy device. A non-implantable or transcutaneous sensor may also be used to monitor cardiac health.
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Citations
34 Claims
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1. A method of monitoring a concentration of suspended particles in a biomedical colloid comprising:
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a. producing an assaulting acoustic field; b. measuring a resultant electric field produced in vivo by particle interaction with the assaulting field; and c. determining the concentration of the suspended particles based on the measured resultant field. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method of monitoring a concentration of suspended proteins in a biomedical colloid, comprising:
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a. producing an assaulting field; b. measuring a resultant field produced by particle interaction with the assaulting field, wherein one of said assaulting field and said resultant field is an electric field; and c. determining the concentration of suspended proteins based on the measured resultant field. - View Dependent Claims (14, 15, 16, 17, 18)
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19. An implantable cardiac therapy device including an implantable biosensor for monitoring a concentration of suspended particles in a biomedical colloid, said implantable biosensor comprising:
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a generator configured to produce an assaulting acoustic field in vivo; a transmitter configured to transmit the assaulting acoustic field; and a receiver configured to detect a resultant electric field produced in vivo by particle interaction with the assaulting acoustic field, said resultant field being indicative of the concentration of suspended particles. - View Dependent Claims (20, 21, 22, 23, 24)
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25. An implantable cardiac therapy device comprising:
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means for producing a first signal, said first signal causing an implantable biosensor to transmit an assaulting field into a biomedical colloid, said assaulting field causing said biomedical colloid to produce a resultant field; means for receiving a second signal representative of said resultant field, wherein one of said assaulting field and said resultant field is an electric field; and means for processing said second signal to produce a value indicative of a concentration of suspended particles in said biomedical colloid. - View Dependent Claims (26, 27, 28, 29)
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30. A method of monitoring a concentration of suspended particles in a biomedical colloid comprising:
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a. producing an assaulting electric field; b. measuring a resultant field produced in vivo by particle interaction with the assaulting field; and c. determining the concentration of the suspended particles based on the measured resultant field. - View Dependent Claims (31, 32)
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33. An implantable cardiac therapy device including an implantable biosensor for monitoring a concentration of suspended particles in a biomedical colloid, said implantable biosensor comprising:
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a generator configured to produce an assaulting field in vivo; a transmitter configured to transmit the assaulting field; and a receiver configured to detect a resultant field produced in vivo by particle interaction with the assaulting field, said resultant field being indicative of the concentration of suspended particles, wherein one of said assaulting field and said resultant field is an electric field. - View Dependent Claims (34)
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Specification