Integrated blood treatment module and extracorporeal blood treatment apparatus

• US 7,223,336 B2
• Filed: 02/05/2004
• Issued: 05/29/2007
• Est. Priority Date: 02/07/2003
• Status: Active Grant

• Current Assignee: Gambro Lundia AB (Baxter International Inc.)
• Original Assignee: Gambro Lundia AB (Baxter International Inc.)
• Inventors: Aberkane, Aziz, Duchamp, Jacques, Tonelli, Claudio, Meyssonnier, Gabriel, Chevallet, Jacques, Pouchoulin, Dominique, Baraldi, Vincenzo, Delnevo, Annalisa, Ribolzi, Francesco, Zaccarelli, Massimo
• Primary Examiner(s): Kim; John
• Application Number:
  US10/771,427
• Publication Number:
  US 20040158189A1
• Time in Patent Office: 1,209 Days
• Field of Search: 210/232, 210/239, 210/240, 210/258, 210/321.6, 210/416.1, 210/249, 604/6.09, 604/6.11, 137/111, 137/269, 138/111, 138/115, 138/118
• US Class Current: 210/232
• CPC Class Codes: A61M 1/3621 Extra-corporeal blood circuits single-needle circuits A61M1/30
• CPC Class Codes: A61M 2205/126 with incorporated membrane filters
• CPC Class Codes: A61M 2205/128 with incorporated valves

Abstract

The invention relates to an integrated blood treatment module (1) comprising a support element (4) and a fluid distribution circuitry associated thereto; the distribution circuitry comprises at least a blood line (44), a portion of which is secured to the support element and defines with the latter at least a U-shaped tube length (44a) designed to cooperate, when in use, with a respective pump (3a). There are then further fluid lines (45, 48, 50, 51) fastened to the support element and defining each at least a U-shaped tube length (45a, 48a, 50a, 51a) with respect to said element and each designed to cooperate, when in use, with a respective pump (3b, 3c, 3d, 3e). The support element has a first zone (274) in which the portion of the blood line is secured, and at least a second zone (275) opposite said first zone, to which all the corresponding further tube lengths are fastened.

Claims

1. An integrated fluid treatment module comprising:

a support element having a main body having;

two first opposite sides and two second opposite sides, said two second opposite sides being shorter than said two first opposite sides, and

at least one peripheral wall protecting away from said two second opposite sides;

fluid distribution circuitry associated to the support element and comprising;

at least a blood line, at least a portion of said blood line being fastened to one of said two second opposite sides of the support element and defining at least a U-shaped tube length with respect to said support element, said U-shaped tube length being designed to cooperate with a respective pump and extending inside the at least one peripheral wall of the support element; and

further fluid lines secured to at least one of said two first opposite sides of the support element, each of said further fluid lines defining at least a U-shaped tube length with respect to said support element, each said U-shaped tube length being designed to cooperate with a respective pump and extending inside the at least one peripheral wall of the support element, said U-shaped tube length of the blood line being longer and having a radius of curvature greater than the tube lengths defined by said further fluid lines;

the support element having a first zone to which the U-shaped tube length of the blood line is fastened, and at least a second zone opposite said first zone to which the U-shaped tube lengths of the further fluid lines are all fastened, said second zone comprising a first half-part and a second half part reciprocally placed side by side and being symmetrical along a longitudinal axis of the main body, the further fluid lines including two fluid lines connected to said first half-part and two fluid lines connected to said second half-part.

2. A module according to claim 1, wherein the further fluid lines comprise at least a discharge line for a waste fluid defining at least a tube length arranged as a U with respect to said support element and fastened to said second half-part.

3. A module according to claim 1, wherein the further fluid lines comprise at least an in-take line for fresh dialysis liquid, said in-take line defining at least a tube length arranged as a U with respect to said support element fastened to said first half-part.

4. A module according to claim 1, wherein said further fluid lines further comprise at least a fluid infusion line defining at least a tube length arranged as a U with respect to said support element and fastened to said first half-part.

5. A module according to claim 1, wherein said further fluid lines further comprise at least an auxiliary pre-infusion line defining at least a tube length arranged as a U with respect to said support element and fastened to said second half-part.

6. A module according to claim 1, wherein the support element further comprises a main body having a front wall delimited by said two first and two second opposite sides, said front wall and said at least one peripheral wall defining a housing compartment.

7. A module according to claim 6, wherein said two first opposite sides and said two second opposite sides are substantially parallel and reciprocally facing.

8. A module according to claim 7, wherein said two first opposite sides have a substantially rectilinear development, each of said two first opposite sides having two curved portions, said two curved portions on at least one of said first opposite sides having a cavity facing the other of said first opposite sides, and

said two second opposite sides have a substantially rectilinear development, at least one of said two second opposite sides having a curved portion positioned between two rectilinear lengths, said curved portion having a cavity facing the other of said two second opposite sides.

9. A module according to claim 8, wherein the first zone is partly delimited by at least one of said two second opposite sides having the curved portion and by a portion of one of said two first opposite sides beside the at least one of said two second opposite sides having the curved portion.

10. A module according to claim 8, wherein the second zone is partly delimited by one of said two second opposite sides without the curved portion and by a portion of said first opposite sides beside said second opposite side without the curved portion.

11. A module according to claim 1, wherein, when the module is associated to an extracorporeal blood treatment apparatus, the first zone of the support element is placed below the second zone of the support element.

12. A module according to claim 1, wherein, when the module is associated to an extracorporeal blood treatment apparatus, the first and second half-part of the second zone of the support element are placed side by side.

13. A module according to claim 8, wherein the U-shaped tube length of the blood line is fastened to the at least one of said two second opposite sides having the curved portion.

14. A module according to claim 3 wherein the tube length of the intake line for fresh dialysis liquid is fastened to one of said two first opposite sides.

15. A module according to claim 2 wherein the tube length of the discharge line for a waste fluid is fastened to one of said two first opposite sides.

16. A module according to claim 4 wherein the tube length of the fluid infusion line is fastened to one of said two first opposite sides.

17. A module according to claim 5 wherein the tube length of the auxiliary pre-infusion line is fastened to one of said two first opposite sides.

18. A module according to claim 1, wherein a length of every U-shaped tube portion is smaller than or the same as (π

R+2R), where R is a respective radius of curvature of the U-shaped tube length.

19. A module according to claim 8, further comprising a support structure associated to the main body and placed laterally with respect to the main body.

20. A module according to claim 19, wherein said support structure is connected to the main body on one of said two first opposite sides.

21. A module according to claim 20, wherein the support structure is connected to the main body on said curved portions of one of said two first opposite sides.

22. A module according to claim 1, further comprising at least a blood treatment unit connected to the support element.

23. A module according to claim 7, wherein said support element comprises at least a first connector and a second connector connected to the main body, said first and second connectors being spaced away one from each other, said first and second connectors being configured to receive one or more corresponding counter-connectors of a blood treatment unit to be mounted onto the support element.

24. A module according to claim 23, further comprising a blood treatment unit connected to the support element, said blood treatment unit comprising:

a housing body;

at least a semipermeable membrane operating inside the housing body defining a first chamber and a second chamber;

a first counter-connector and a second counter-connector associated to the housing body and fastened to the respective first and second connectors associated to the main body, at least one of said first and second counter-connectors being in fluid communication with the second chamber of the treatment unit and with respective first end portions of said connectors;

at least an access port to said first chamber; and

at least an exit port from said first chamber.

25. A module according to claim 23, further comprising a support structure associated to the main body and placed laterally with respect to the main body, the first and second connectors and the support structure being positioned laterally with respect to the main body on one of said two first opposite sides.

26. A module according to claim 1, wherein the first half-part and the second half-part are specularly symmetrical with respect to a longitudinal axis of the main body.

32. An apparatus for extracorporeal blood treatment comprising:

a body, a number of pumps provided on a surface of the body, the number of pumps being designed to cooperate with a suitable fluid distribution circuitry to be associated to the apparatus, at least one of said number of pumps being a blood pump designed to cooperate with a respective blood line of the distribution circuitry, wherein the surface of the body has a first zone having said blood pump and at least a second zone, opposite said first zone, having the other of said number of pumps; and

an integrated fluid treatment module according to claim 22 having the U-shaped tube lengths of the blood line and of the further fluid lines secured and cooperating with the number of pumps of said apparatus.

33. An apparatus according to claim 32, wherein said blood pump and the other of said number of pumps are peristaltic pumps, each comprising a moving arm rotating around a fulcrum, and an active element fastened to the moving arm, said active element operating on at least a deformable tube length associated with the peristaltic pump, the moving arm of the blood pump being longer than that of the other of said number of pumps.

27. An integrated fluid treatment module comprising:

a support element including;

a front wall having two first opposite sides and two second opposite sides,

the two first opposite sides being substantially parallel and reciprocally facing, said two first opposite sides having a substantially rectilinear development, each of said two first opposite sides having two curved portions, wherein cavities formed by each of said two curved portions on one of said two first opposite sides face the other of said two first opposite sides; and

the two second opposite sides being substantially parallel and reciprocally facing, said two second opposite sides having a substantially rectilinear development, at least one of said two second opposite sides having a curved portion placed between two rectilinear lengths, a cavity formed by said curved portion on one of said two second opposite sides facing the other of said two second opposite sides, at least a peripheral wall projecting away from said two second opposite sides;

fluid distribution circuitry associated to the support element and comprising;

at least one blood line, at least a portion of said at least one blood line being fastened to the peripheral wall of the support element corresponding to the curved portion of one of said two second opposite sides, said at least one blood line defining at least one U-shaped tube length with respect to said support element, said at least one U-shaped tube length being configured to cooperate with a respective pump and to extend inside the peripheral wall of the support element; and

further fluid lines secured to the peripheral wall of the support element corresponding to the curved portions of said two first opposite sides, each of said further fluid lines defining at least one U-shaped tube length with respect to said support element, each of said at least one U-shaped tube length being configured to cooperate with a respective pump and to extend inside the peripheral wall of the support element.

28. A module according to claim 27, wherein said support element has first zone to which the U-shaped tube length of the blood line is fastened, and at least a second zone opposite said first zone to which the U-shaped tube lengths of the further fluid lines are fastened.

29. A module according to claim 28, wherein said second zone comprises a first half-part and a second half-part reciprocally placed side by side, said first and second half-parts being symmetrical to a longitudinal axis of the main body, the further fluid lines being fastened on said second zone including at least two fluid lines connected to said first half-part and at least two fluid lines connected to said second half-part.

30. An apparatus for extracorporeal blood treatment comprising:

a body, a number of pumps provided on a surface of the body, the number of pumps being designed to cooperate with a suitable fluid distribution circuitry to be associated to the apparatus, at least one of said number of pumps being a blood pump designed to cooperate with a respective blood line of the distribution circuitry, wherein the surface of the body has a first zone having said blood pump and at least a second zone, opposite said first zone, having the other of said number of pumps; and

an integrated fluid treatment module according to claim 27 having the U-shaped tube lengths of the blood line and of the further fluid lines secured and cooperating with the number of pumps of said apparatus.

31. An apparatus according to claim 30, wherein said blood pump and the other of said number of pumps are peristaltic pumps, each comprising a moving arm rotating around a fulcrum, and an active element fastened to the moving arm, said active element operating on at least a deformable tube length associated with the peristaltic pump, the moving arm of the blood pump being longer than that of the other of said number of pumps.