Multipolar medical electrical lead

• US 7,225,035 B2
• Filed: 06/24/2004
• Issued: 05/29/2007
• Est. Priority Date: 06/24/2004
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Brabec, Scott J., Hine, Douglas S.
• Primary Examiner(s): LAYNO, CARL HERNANDZ
• Application Number:
  US10/876,003
• Publication Number:
  US 20050288761A1
• Time in Patent Office: 1,069 Days
• Field of Search: None
• US Class Current: 607/122
• CPC Class Codes: A61N 1/056 Transvascular endocardial electrode systems
• CPC Class Codes: A61N 2001/0585 Coronary sinus electrodes

Abstract

A pacing lead includes a first pacing cathode coupled to a first conductor, a second pacing cathode coupled to a second conductor, and a flexible anode coupled to a third conductor. The flexible anode has a length less than approximately 10 millimeters and is spaced apart from and proximal to the first pacing cathode and spaced apart from and distal to the second pacing cathode. The spacing between the anode and the first pacing cathode is approximately equal to the spacing between the anode and the second pacing cathode.

Claims

1. A medical electrical lead, comprising:

an elongate lead body including a first conductor, a second conductor and a third conductor extending therein and electrically isolated from one another;

a first cathode electrode coupled to the first conductor;

a second cathode electrode coupled to the second conductor; and

a flexible anode electrode having a length less than approximately 10 millimeters and a surface area greater than a surface area of each of the first cathode electrode and the second cathode electrode, being coupled to the third conductor, spaced apart from and proximal to the first cathode electrode and spaced apart from and distal to the second cathode electrode, the spacing between the anode electrode and the first cathode electrode being approximately equal to the spacing between the anode electrode and the second cathode electrode.

2. The lead of claim 1, wherein a length of the flexible anode electrode is between approximately 3 millimeters and approximately 10 millimeters.

3. The lead of claim 2, wherein the length is approximately 8 millimeters.

4. The lead of claim 1, wherein an outer diameter of the flexible anode electrode is between approximately 0.75 millimeters and approximately 2 millimeters.

5. The lead of claim 4, wherein the outer diameter is approximately 1.3 millimeters.

6. The lead of claim 1, wherein a length of the flexible anode electrode is between approximately 3 millimeters and approximately 10 millimeters and an outer diameter of the flexible anode electrode is between approximately 0.75 millimeters and approximately 2 millimeters.

7. The lead of claim 1, wherein the first cathode electrode is positioned proximal to a distal end of the lead body.

8. The lead of claim 1, wherein the first cathode electrode terminates a distal end of the lead body.

9. The lead of claim 1, wherein the flexible anode electrode comprises a conductive polymer.

10. The lead of claim 1, wherein the flexible anode electrode comprises a coiled conductive wire.

11. The lead of claim 1, wherein the flexible anode electrode includes a coating to reduce post-pace polarization.

12. The lead of claim 1, wherein a ratio of a surface area of the flexible anode electrode to a surface area of each of the first cathode electrode and the second cathode electrode is greater than approximately 3:

1.

13. The lead of claim 12, wherein the ratio is greater than or equal to approximately 6:

1.

14. The lead of claim 1, wherein the spacing between the flexible anode electrode and the first cathode electrode is between approximately 5 millimeters and approximately 15 millimeters.

15. The lead of claim 1, wherein the spacing between the flexible anode electrode and the first cathode electrode is between approximately 9 millimeters and approximately 15 millimeters.

16. The lead of claim 1, further comprising an in-line connector terminating a proximal end of the lead body;

the in-line connector comprising a first contact coupled to the first conductor, a second contact coupled to the second conductor and a third contact coupled to the a third conductor;

wherein the third contact is positioned distal to the first contact and the second contact.

17. The lead of claim 1, further comprising a bifurcated connector terminating a proximal end of the lead body;

the bifurcated connector including a first contact coupled to the first conductor and a second contact coupled to the third conductor, the first contact and the second contact positioned on a first leg, and a third contact coupled to the second conductor and a fourth contact coupled to the third conductor, the third contact and the fourth contact positioned on a second leg.

18. The pacing lead of claim 17, wherein the first contact terminates a proximal end of the first leg and the third contact terminates a proximal end of the second leg.

19. The pacing lead of claim 17, wherein each leg of the bifurcated connector conforms to an industry standard.

20. A method for delivering a pacing pulse to a heart, the method comprising the steps of:

positioning a distal portion of a pacing lead within a coronary vein, the distal portion including a first pacing cathode, a second pacing cathode and a flexible anode having a length less than approximately 10 millimeters and a surface area greater than a surface area of each of the first pacing cathode and the second pacing cathode, the flexible anode spaced apart from and proximal to the first pacing cathode and spaced apart from and distal to the second pacing cathode, the spacing between the anode and the first pacing cathode being approximately equal to the spacing between the anode and the second pacing cathode;

selecting a one of the first pacing cathode and the second pacing cathode to form a bipolar pair with the flexible anode;

delivering a pacing pulse to the heart via the bipolar pair.

21. The method of claim 20, further comprising the steps of:

applying a test pacing pulse to each of the first pacing cathode and the second pacing cathode; and

measuring pacing thresholds of the first pacing cathode and the second pacing cathode; and

wherein the step of selecting the one from the first pacing cathode and the second pacing cathode is based upon the pacing thresholds.

22. The method of claim 20, further comprising the steps of:

applying test pacing pulses to each of the first pacing cathode and the second pacing cathode; and

observing for phrenic nerve stimulation resulting from the pacing pulses; and

wherein the step of selecting the one from the first pacing cathode and the second pacing cathode is based upon an absence of phrenic nerve stimulation.

23. The method of claim 20, further comprising the steps of:

applying test pacing pulses to each of the first pacing cathode and the second pacing cathode; and

observing a hemodynamic response of the heart resulting from the pacing pulses; and

wherein the step of selecting the one from the first pacing cathode and the second pacing cathode is based upon the hemodynamic response.

24. The method of claim 20, further comprising the step of sensing an evoked response of the pacing pulse from the bipolar pair by means of another of the first pacing cathode and the second pacing cathode that is not selected.

25. The method of claim 20, wherein:

the step of selecting the one from the first pacing cathode and the second pacing cathode comprises selecting a connector leg from a first connector leg and a second connector leg of a bifurcated connector terminating a proximal end of the lead;

wherein the first connector leg includes a first contact coupled to the first conductor and a second contact coupled to the third conductor and the second connector leg includes a third contact coupled to the second conductor and a fourth contact coupled to the third conductor.