Surgical microwave ablation assembly

• US 7,226,446 B1
• Filed: 09/12/2000
• Issued: 06/05/2007
• Est. Priority Date: 05/04/1999
• Status: Expired due to Fees

• Current Assignee: Maquet Cardiovascular LLC (Getinge AB)
• Original Assignee: ARX, Inc. (Cobham PLC)
• Inventors: Morin, Patrick, Mody, Dinesh, Chin, Sing-Fatt, Berube, Dany
• Primary Examiner(s): Gibson; Roy D.
• Assistant Examiner(s): ROANE, AARON F
• Application Number:
  US09/660,466
• Time in Patent Office: 2,457 Days
• Field of Search: 607100- 2, 607/154, 607/156, 607/96, 606 31- 34, 606/41, 606/46
• US Class Current: 606/33
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2018/00357 Endocardium
• CPC Class Codes: A61B 2018/1425 Needle
• CPC Class Codes: A61B 2018/183 characterised by the type of antenna
• CPC Class Codes: A61B 2018/1861 with an instrument inserted into a body lumen or cavity, e.g. a catheter

Abstract

An ablation assembly capable of ablating tissues inside the cavity of an organ is disclosed. The ablation assembly generally includes an ablative energy source and an ablative energy delivery device coupled to the ablative energy source. The ablative energy delivery device is configured for delivering ablative energy sufficiently strong to cause tissue ablation. The ablative energy delivery device generally includes a penetration end adapted to penetrate through a wall of an organ and an angular component that is used to position the device inside the organ after the device has penetrated through the wall of the organ.

Claims

1. A system for ablating an interior tissue region of an organ or duct within a body of a patient comprising:

an ablation tool including an elongated antenna device electrically coupled to a coaxial transmission line that is electrically coupled to a source of microwave energy for delivering sufficient microwave energy to the antenna device to effect ablation of a tissue region within the interior of the organ or duct, the coaxial transmission line including an inner conductor, an outer conductor and a dielectric medium disposed between the inner and outer conductors, the antenna device including an antenna that is coupled to a distal end of the inner conductor of the coaxial transmission line and an enclosure that encapsulates the antenna with a dielectric material; and

an introducer that is not connected to the source of microwave energy, said introducer having a proximal end, a sharpened distal end for penetrating through a wall of the organ or duct, and a lumen which is sized and dimensioned for slidable movement of the antenna device therein, the antenna device being configured to be deployed into the interior of the organ or duct through the sharpened distal end of the introducer with a deployed shape that is straight and at a skewed angular orientation relative to a longitudinal axis of the introducer, over an entire exposed length of the antenna device that extends distally from the introducer, to orient the antenna device in a direction towards and substantially parallel to an interior portion of the penetrated wall for producing a linear lesion at the tissue region of the penetrated wall which is targeted for ablation.

2. A system for ablating an interior tissue region of an organ or duct within a body of a patient comprising:

an ablation tool including an elongated antenna device electrically coupled to a coaxial transmission line that is electrically coupled to a source of microwave energy, the coaxial transmission line delivering microwave energy to the antenna device so as to effect ablation of a tissue region within the interior of the organ or duct, the coaxial transmission line including an inner conductor, an outer conductor and a dielectric medium disposed between the inner and outer conductors, the antenna device including an antenna that is coupled to a distal end of the inner conductor of the coaxial transmission line and an enclosure that encapsulates the antenna with a dielectric material; and

an introducer configured to carry at least a portion of the ablation tool, the introducer having a proximal end, a sharpened distal end for penetrating through a wall of the organ or duct, and at least one lumen which is sized and dimensioned for slidable receipt of at least the antenna device of the ablation tool therethrough, the antenna device being configured to be deployed into the interior of the organ or duct through the sharpened distal end of the introducer, wherein upon deployment the antenna device assumes a predetermined position in a straight direction, over an entire exposed length of the antenna device that extends distally from the introducer, towards the tissue region targeted for ablation and substantially parallel to the tissue region targeted for ablation, wherein said ablation tool comprises a steering mechanism associated with the proximal end of the tool which, upon manipulation, is configured to cause at least a portion of the antenna device to assume an angular orientation relative to a longitudinal axis of the tool.

3. The system of claim 2 wherein said angular orientation is between about 0 and 90 degrees relative to the longitudinal axis of the tool.

4. The system of claim 2 wherein said angular orientation is between about 45 and 135 degrees relative to the longitudinal axis of the tool.

5. The system of claim 2 wherein the antenna further comprises a microwave antenna which is electrically coupled to the transmission line.

6. A microwave ablation device for ablating an interior portion of a wall of a beating heart, the microwave ablation device comprising:

a probe configured to penetrate the wall of the beating heart, the probe having a proximal end portion and a distal end portion having a sharpened distal end and wherein said probe is not configured to deliver ablation energy; and

a microwave energy delivery antenna portion slidably disposed within the distal end portion of the probe, said sharpened distal end of said probe being configured to penetrate the wall of the beating heart to facilitate deployment from the distal end within an interior cavity of the beating heart of the microwave energy portion, with a deployed shape that is straight and at a skewed angular orientation relative to a longitudinal axis of the probe, over an entire exposed length of the antenna portion that extends distally from the probe, and configured to substantially to match the shape of the interior portion of the wall for linearly ablating the interior portion of the wall of the beating heart proximate the deployed microwave energy delivery portion.

7. The device of claim 6 wherein said energy delivery portion comprises a microwave antenna which is located within said distal end portion of the shaft.

8. The device of claim 6 wherein said distal end portion of the device is preshaped to extend at an angle relative to a longitudinal axis of the shaft.

9. The device of claim 8 wherein said distal end portion extends at an angle of between about 0 and 90 degrees relative to the longitudinal axis of the shaft.

10. The device of claim 8 wherein said distal end portion extends at an angle of between about 45 and 135 degrees relative to the longitudinal axis of the shaft.

11. The device of claim 6 wherein said distal end portion comprises a dielectric material which substantially surrounds the distal end portion.

12. An ablation device for ablating heart tissue, the device comprising:

an elongated shaft that is not connected to a source of ablation energy, said elongated shaft having a proximal end portion and a sharpened distal end; and

a pre-shaped elongated energy delivery antenna portion slidably disposed within the elongated shaft proximate to the distal end, said energy delivery portion including a shape memory material that facilitates bending following deployment of the energy delivery portion from the distal end and that facilitates straightening in response to retraction of the energy delivery portion relative to the distal end of the elongated shaft, the deployed shape of the elongated energy portion being straight and at a skewed angular orientation relative to a longitudinal axis of the probe, over an entire exposed length of the antenna portion that extends distally from the elongated shaft, and having a contour of an inner wall of a heart to substantially conform the elongated energy delivery portion to the inner wall of the heart with the distal end of the elongated shaft penetrating through the inner wall of the heart.

13. The device of claim 12 wherein said elongated energy delivery portion is pre-shaped to extend substantially straight from the distal end at a skewed angle relative to a longitudinal axis of the shaft.

14. The device of claim 13 wherein said energy delivery portion extends at an angle greater than 0 and less than 90 degrees relative to the longitudinal axis of the shaft.

15. The device of claim 13 wherein said energy delivery portion extends at an angle of between about 45 and 135 degrees relative to the longitudinal axis of the shaft.

16. The device of claim 12 wherein the energy delivery portion is configured to substantially conform to a tissue region of the inner wall surrounding a pulmonary vein.

17. The device of claim 12 wherein the energy delivery portion is configured to substantially conform to at least a portion of a lateral inner wall of the right atrium.

20. The ablation device as recited in claim 12 wherein the energy delivery portion is configured to produce an electromagnetic field that is concentrated on a side of the energy delivery portion oriented proximate to the inner wall of the heart in order to produce a linear lesion at the inner wall of the heart.

21. The ablation device of claim 12, further comprising an antenna enclosure encapsulating at least a portion of said antenna portion.

22. The ablation device of claim 21, wherein said antenna enclosure comprises a dielectric material.

18. An ablation assembly, comprising:

a probe having a sharpened distal end configured for percutaneously penetrating through a wall of an organ for introducing a longitudinal energy delivery member into a cavity within the organ, the longitudinal energy delivery antenna member being deployable from the distal end of the probe within the cavity of the organ, and being configured to assume a deployed shape that is straight and at a skewed angular orientation relative to a longitudinal axis of the probe, over an entire exposed length of the antenna member that extends distally from the distal end of the probe, to conform to an inner wall of the organ for producing a substantially linear lesion on the inner wall of the organ in response to ablative energy delivered to the longitudinal energy delivery member, and wherein the probe is not configured to deliver ablative energy.

19. The ablation assembly as recited in claim 18 in which the longitudinal energy delivery member is deployable from the distal end at an angular position relative to an elongated axis of the probe near the distal end thereof that places the longitudinal energy delivery member substantially parallel to the inner wall of the organ with each longitudinal portion of the longitudinal energy delivery member equidistant from the inner wall of the organ.

23. An ablation system for ablating an interior tissue region of an organ or duct within a body of a patient, said system comprising:

a probe configured to penetrate a wall of the organ or duct, but not to deliver ablation energy, the probe having a proximal end portion and a distal end portion having a sharpened distal end; and

an ablation tool configured to be slidably passed within said probe, said ablation tool comprising an ablation antenna element at a distal end thereof and an ablation energy supply line connected proximally to said ablation antenna element, said ablation antenna element having a first, straight configuration assumed when being passed through said probe, and a second, bent configuration assumed when said ablation antenna element extends distally from said distal end of said probe, wherein said ablation antenna element is bent with respect to a longitudinal axis of said probe and extends straight away from a bend where said ablation element is bent, over an entire length of the antenna element that extends distally from a distal end of the probe.

24. The ablation system of claim 23, wherein said ablation element comprises a microwave antenna.

25. The ablation system of claim 23, wherein said probe and said ablation tool are independent components and wherein said ablation tool can be completely removed from within said probe.

26. The ablation system of claim 23, wherein said ablation tool and probe are integrally provided within said system.

27. The ablation system of claim 26, further comprising a handle proximally connected to said probe, and wherein longitudinal sliding of said ablation tool within said probe is facilitated via said handle.

28. The ablation system of claim 23, further comprising a biasing member configured to bias said ablation element from said substantially straight configuration to said bent configuration.