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Optical sensor containing particles for in situ measurement of analytes

  • US 7,228,159 B2
  • Filed: 06/27/2002
  • Issued: 06/05/2007
  • Est. Priority Date: 07/10/2001
  • Status: Active Grant
First Claim
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1. A sensor for in vivo measurement of an analyte, comprising a plurality of particles having a size such that when implanted in a body of a mammal at an implantation site the particles can be ingested by macrophages and transported away from the implantation site, wherein each particle of the sensor contains the components of an assay having a readout which is an optical signal detectable transdermally by external optical means, and wherein the particles are each contained within a biodegradable material preventing ingestion by the macrophages.

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