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Compositions and methods for enhanced mucosal delivery of Y2 receptor-binding peptides and methods for treating and preventing obesity

  • US 7,229,966 B2
  • Filed: 02/17/2004
  • Issued: 06/12/2007
  • Est. Priority Date: 12/17/2002
  • Status: Expired due to Fees
First Claim
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1. A pharmaceutical device comprising:

  • a. an aqueous solution formulation of a Y2 receptor binding peptide at a concentration sufficient to produce therapeutically effective plasma concentrations and L-α

    -phosphatidylcholine didecanoyl (DDPC); and

    b. an actuator able to produce an aerosol of said solution, wherein the spray pattern ellipticity ratio of said aerosol is between 1.00 and 1.40 when measured at a height of between 0.5 cm and 10 cm distance from the actuator tip.

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