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Optical methods for tissue analysis

  • US 7,231,243 B2
  • Filed: 10/30/2001
  • Issued: 06/12/2007
  • Est. Priority Date: 10/30/2000
  • Status: Expired due to Fees
First Claim
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1. A method of analyzing tissue, the method comprising:

  • illuminating a tissue with coherent or partially coherent light;

    receiving light reflected from the tissue at a detector and forming series of speckle patterns;

    analyzing changes in the speckle patterns at time intervals sufficient to measure changes caused by microscopic motion of objects within the tissue, wherein the tissue is at least one of in vivo or an internal tissue; and

    compensating for macroscopic motion to isolate the microscopic motion.

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