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Delivery of a sympatholytic cardiovascular agent to the central nervous system to counter heart failure and pathologies associated with heart failure

  • US 7,232,435 B2
  • Filed: 02/06/2004
  • Issued: 06/19/2007
  • Est. Priority Date: 02/06/2004
  • Status: Expired due to Fees
First Claim
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1. A method of delivering a drug dosage from a drug dispenser to receptors of the central nervous system of a patient'"'"'s body to therapeutically treat one of pre-existing symptoms of heart failure (“

  • HF”

    ) and pre-existing pathologies associated with HF, the method comprising the steps of;

    surgically implanting a drug infusion catheter with a distal drug delivery portion disposed at a predetermined central nervous system site;

    coupling a proximal end of the drug infusion catheter to a drug delivery pump;

    monitoring the patient for at least one pre-existing of symptoms of HF and pre-existing pathologies associated with HF; and

    in response to a positive detection of one pre-existing of HF and pre-existing pathologies associated with HF, operating the drug delivery pump to discharge a predetermined dosage of a sympatholytic cardiovascular agent to a central nervous system site effective to alleviate at least one of the pre-existing symptoms of HF and the pre-existing pathologies associated with HF.

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