Biopsy and sampling needle antennas for magnetic resonance imaging-guided biopsies

• US 7,236,816 B2
• Filed: 04/24/2002
• Issued: 06/26/2007
• Est. Priority Date: 04/25/1996
• Status: Expired due to Fees

• Current Assignee: Johns Hopkins University
• Original Assignee: Johns Hopkins University
• Inventors: Kumar, Ananda, Atalar, Ergin, Ocali, Ogan
• Primary Examiner(s): Smith; Ruth S.
• Application Number:
  US10/131,601
• Publication Number:
  US 20030028094A1
• Time in Patent Office: 1,889 Days
• Field of Search: 600/410, 600/411, 600/423, 600/562, 600/564, 600/567, 324/307, 324/309, 324/318, 324/322
• US Class Current: 600/411
• CPC Class Codes: A61B 10/0275 with sample notch, e.g. on the side of inner stylet
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 2090/374 NMR or MRI
• CPC Class Codes: A61B 2090/3958 emitting a signal
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: G01R 33/287 involving active visualization of interventional instruments, e.g. using active tracking RF coils or coils for intentionally creating magnetic field inhomogeneities
• CPC Class Codes: G01R 33/34084 implantable coils or coils being geometrically adaptable to the sample, e.g. flexible coils or coils comprising mutually movable parts
• CPC Class Codes: G01R 33/341 comprising surface coils
• CPC Class Codes: G01R 33/3628 Tuning/matching of the transmit/receive coil
• CPC Class Codes: G01R 33/3657 Decoupling of multiple RF coils wherein the multiple RF coils do not have the same function in MR, e.g. decoupling of a transmission coil from a receive coil

Abstract

Herein is disclosed a magnetic resonance imaging antenna, including an inner conductor, an outer shield slideably displaceable with respect to the inner conductor, and an insulator electrically insulating the inner conductor from the outer shield. Herein is disclosed a biopsy needle antenna, including a magnetic resonance imaging antenna, having an outer shield, and an inner conductor electrically insulated from the outer shield by a dielectric; and a biopsy needle electrically connected to the inner conductor and electrically insulated from the outer shield by the dielectric. Herein is disclosed a method of obtaining a sample with magnetic resonance imaging guidance, including providing a sampling needle magnetic resonance imaging antenna, advancing the antenna to a structure from which the sample is to be taken, detecting magnetic resonance data by the antenna, and coupling the sample to the antenna.

Claims

1. A biopsy needle antenna, comprising:

a magnetic resonance imaging antenna, having;

an outer shield; and

an inner conductor electrically insulated from the outer shield by a dielectric; and

a biopsy needle electrically connected to the inner conductor and electrically insulated from the outer shield by the dielectric.

2. The biopsy needle antenna of claim 1, further comprising a sheath, the biopsy needle being slideably displaceable within the sheath.

3. The biopsy needle antenna of claim 2, wherein the sheath is defined by the outer shield.

4. The biopsy needle antenna of claim 1, wherein at least one of the outer shield, the inner conductor, and the biopsy needle comprise a magnetic resonance compatible material.

5. The biopsy needle antenna of claim 1, wherein the biopsy needle antenna is configured with circuitry that receives magnetic resonance spectroscopy information from a sample.

6. The biopsy needle antenna of claim 1, wherein the outer shield and the inner conductor form a coaxial cable.

7. The biopsy needle antenna of claim 6, wherein the coaxial cable is electrically interconnected to an impedance matching circuit.

8. The biopsy needle antenna of claim 1, wherein at least one of the outer shield, the inner conductor, and the biopsy needle comprise a superelastic material.

9. The biopsy needle antenna of claim 1, wherein the outer shield is slideably displaceable with respect to the inner conductor.

10. The biopsy needle antenna of claim 1, wherein the inner conductor comprises an obturator and the outer shield comprises a cannula slideably displaceable over the obturator.

11. The biopsy needle antenna of claim 10, wherein the obturator further comprises a side-slit.

12. The biopsy needle antenna of claim 11, wherein the cannula comprises a distal end having a cutting edge, the cutting edge slideably displaceable over the side-slit.

13. The biopsy needle antenna of claim 11, wherein the cannula covers at least the side-slit.

14. The biopsy needle antenna of claim 10, wherein the cannula is spring-loaded.

15. The biopsy needle antenna of claim 10, wherein at least a portion of the obturator protrudes from a distal end of the cannula.

16. The biopsy needle antenna of claim 1, further comprising a spring coupled to the outer shield.

17. The biopsy needle of claim 16, wherein the spring is electrically coupled to the outer shield.

18. The biopsy needle antenna of claim 1, wherein the dielectric comprises at least one of fluroethylene polymer, tetrafluoroethylene, polyester, polyethylene, silicone, metal oxide, glass, and polyethylene terephthalate.

19. The biopsy needle antenna of claim 1, wherein the dielectric is covered by a lubricious coating.

20. The biopsy needle antenna of claim 19, wherein the lubricious coating comprises at least one of polyvinylpyrrolidone, polyacrylic acid, and silicone.

21. The biopsy needle antenna of claim 1, wherein the inner conductor and outer shield are electrically coupled to an interface.

22. The biopsy needle antenna of claim 21, wherein the interface comprises at least one of a tuning-matching circuit, a balun circuit, a decoupling circuit, and a variable capacitor.

23. The biopsy needle antenna of claim 21, wherein the interface resides upstream of the biopsy needle and is configured to couple to an MRI scanner.

24. A sampling needle antenna, comprising:

a cannula being formed at least in part of a conductive material and defining an outer shield;

an obturator being formed at least in part of a conductive material and defining an inner conductor, the obturator being slideably displaceable relative to the cannula; and

an insulator electrically insulating the cannula from the obturator;

wherein the outer shield, the inner conductor, and the insulator form a magnetic resonance imaging antenna.

25. A method of obtaining a sample with magnetic resonance imaging guidance, comprising:

providing a magnetic resonance imaging antenna, wherein the magnetic resonance imaging antenna comprises an outer shield and an inner conductor electrically insulated from the outer shield by a dielectric, and wherein a sampling needle is electrically connected to the inner conductor and electrically insulated from the outer shield by the dielectric;

advancing the antenna to a structure from which the sample is to be taken;

detecting magnetic resonance data by the antenna; and

coupling the sample to the antenna and the sampling needle whereby the sample is obtained.

26. The method of claim 25, wherein the sample is a biopsy.

27. The method of claim 25, wherein the inner conductor comprises anobturator and the outer shield comprises a cannula, the obturator slideably displaceable relative to the cannula.

28. The method of claim 25, further comprising coupling the magnetic resonance data to an MRI scanner to form a magnetic resonance image.

29. The method of claim 28, wherein the image formed is a composite image.

30. The method of claim 28, wherein the image formed is a high resolution image.

31. A method of obtaining a sample with magnetic resonance imaging guidance, comprising:

providing a sampling needle magnetic resonance imaging antenna;

advancing the antenna to a structure from which the sample is to be taken;

detecting magnetic resonance data by the antenna; and

coupling the sample to the antenna,

wherein the antenna comprises a cannula including an outer shield, an obturator including an inner conductor, the obturator slideably displaceable relative to the cannula, and an insulator electrically insulating the outer shield from the inner conductor; and

wherein the coupling includes trapping the sample between the cannula and the obturator.

32. The method of claim 31, wherein trapping includes moving at least one of the cannula and the obturator relative to the other.

33. A method of obtaining a magnetic resonance imaging-guided biopsy, comprising:

providing a biopsy needle antenna, having;

a magnetic resonance imaging antenna, including;

an outer shield; and

an inner conductor electrically insulated from the outer shield by a dielectric; and

a biopsy needle electrically connected to the inner conductor and electrically insulated from the outer shield by the dielectric;

advancing the needle to a lesion;

imaging the lesion with the antenna; and

taking a sample of the lesion with the needle.