Systems, methods and apparatuses for pumping cassette-based therapies

• US 7,238,164 B2
• Filed: 12/31/2002
• Issued: 07/03/2007
• Est. Priority Date: 07/19/2002
• Status: Expired due to Fees

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Childers, Robert W., Grippo, Paul, Hopping, Andrew D., Yang, Tahua, Bowman, Joseph H. Jr., Vescovi, David, Avoy, Richard, Yu, Alex, Kellam, Benjamin, Booras, John, Jerrell, Jeffrey W., Lauman, Brian, Shang, Sherwin, Howard, David
• Primary Examiner(s): Zalukaeva; Tatyana
• Assistant Examiner(s): Deak; Leslie R.
• Application Number:
  US10/335,646
• Publication Number:
  US 20040019313A1
• Time in Patent Office: 1,645 Days
• Field of Search: 210/645, 210/646, 210/252, 210/257.2, 210/258, 210/260, 210/256, 210/257.1, 210/739, 210/90, 210/416.1, 417/477.2, 417/437, 417/439, 417/472, 417/474, 417/507, 417/508, 417/395, 417/479, 604/4.01, 604/5.01, 604/5.04, 604/6.11, 604/6.1, 604/27, 604/29, 604/30, 604 65- 67, 604/131, 604/151
• US Class Current: 604/6.11
• CPC Class Codes: A61M 1/1522 the interface being evacuated interfaces to enhance contact
• CPC Class Codes: A61M 1/154 with sensing means or components thereof
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/1562 Details of incorporated reservoirs
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/281 Instillation other than by gravity
• CPC Class Codes: A61M 1/284 Continuous flow peritoneal dialysis [CFPD]
• CPC Class Codes: A61M 2205/122 using evacuated interfaces to enhance contact

Abstract

The present invention provides systems, methods and apparatuses for medical fluid delivery systems that employ a pumping cassette. In particular, the present invention provides systems, methods and apparatuses for cassette-based dialysis therapies including hemodialysis, hemofiltration, APD (including tidal modalities) and CFPD. The embodiments described include a combined pump/valve housing, a fail safe pump/valve arrangement, a cassette auto-alignment feature, a pumping membrane material, a multiplexing valve arrangement, an expert fluid pumping management system, an integral port vent and an in-line air separation chamber and combinations of each of these.

Claims

1. A system for performing dialysis comprising:

a patient line;

a disposable cassette in communication with the patient line;

a pump spring biasing a pump head to close a pumping portion of the cassette;

a valve spring biasing a valve plunger to close a valve portion of the cassette; and

a source that applies negative pressure to compress the pump spring and valve spring, allowing fluid to flow into the pumping portion and through the valve portion of the cassette.

2. The system of claim 1, wherein the negative pressure is further configured to draw a membrane of the cassette toward the pump head and valve plunger when compressing the springs.

3. The system of claim 1, which includes at least one diaphragm configured to create, at least in part, a sealed vacuum chamber for the pump and valve springs.

4. The system of claim 1, which includes a plurality of spring-loaded pump heads configured to operate with the cassette.

5. The system of claim 1, which includes a plurality of the valve plungers configured to operate with the cassette.

6. The system of claim 1, which includes a plurality of membranes attached to opposing sides of the cassette and at least one valve plunger configured to operate with each membrane.

7. The system of claim 1, wherein the disposable cassette is in fluid communication with at least one of:

a fluid supply and a fluid regeneration line.

8. The system of claim 1, which is configured to perform a dialysis therapy selected from the group consisting of:

continuous flow peritoneal dialysis, automated peritoneal dialysis, tidal flow peritoneal dialysis, hemofiltration and hemodialysis.

9. The system of claim 1, wherein the pumping portion of the cassette is configured to communicate with at least two fluid sources.

10. The system of claim 1, wherein the pumping portion of the cassette is configured to communicate with at least two fluid destinations.

11. The system of claim 1, wherein the pump head is shaped to align the cassette before pumping begins.

12. The system of claim 1, wherein the cassette includes an integrally formed port vent.

13. The system of claim 1, which includes a controller with a control scheme configured to control the valve plunger so that only one fluid flows through the pumping portion at one time.

14. The system of claim 1, the negative pressure being a first negative pressure, and further including a second negative pressure applied to pull a membrane of the cassette toward the pump head and valve plunger when the first negative pressure is applied to compress the pump spring and valve spring.