Compliant tissue sealants
First Claim
1. A method for reducing leakage of bodily fluids or air, comprising applying to an appropriate area of the body a solution containing a biodegradable, biocompatible polymerizable monomer and an initiator therefore;
- and polymerizing the solution to seal the body area with a polymer coating.
1 Assignment
0 Petitions
Accused Products
Abstract
An improved barrier or drug delivery system which is highly adherent to the surface to which it is applied is disclosed, along with methods for making the barrier. In the preferred embodiment, the system is compliant, in that it is capable of conforming to the three dimensional structure of a tissue surface as the tissue bends and deforms during healing processes. The barrier or drug delivery systems is formed as a polymeric coating on tissue surfaces by applied a polymerizable monomer to the surface, and then polymerizing the monomer. The polymerized compliant coating preferably is biodegradable and biocompatible, and can be designed with selected properties of compliancy and elasticity for different surgical and therapeutic applications.
115 Citations
17 Claims
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1. A method for reducing leakage of bodily fluids or air, comprising applying to an appropriate area of the body a solution containing a biodegradable, biocompatible polymerizable monomer and an initiator therefore;
- and polymerizing the solution to seal the body area with a polymer coating.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
Specification