Motion compensation for magnetic resonance imaging

• US 7,239,136 B2
• Filed: 04/27/2005
• Issued: 07/03/2007
• Est. Priority Date: 04/27/2005
• Status: Active Grant

• Current Assignee: University Health Network
• Original Assignee: University Health Network
• Inventors: Wright, Graham A., White, Lawrence M., Merchant, Naeem, Sussman, Marshall S.
• Primary Examiner(s): Gutierrez; Diego
• Assistant Examiner(s): Vargas; Dixomara
• Application Number:
  US11/115,308
• Publication Number:
  US 20060244445A1
• Time in Patent Office: 797 Days
• Field of Search: None
• US Class Current: 324/307
• CPC Class Codes: G01R 33/56391 involving motion of a part of the sample with respect to another part of the sample, e.g. MRI of active joint motion
• CPC Class Codes: G01R 33/565 Correction of image distortions, e.g. due to magnetic field inhomogeneities
• CPC Class Codes: G01R 33/5676 Gating or triggering based on an MR signal, e.g. involving one or more navigator echoes for motion monitoring and correction

Abstract

An MRI system and method for acquiring motion-compensated MR image data of an object. The MRI system includes an MRI device for generating a uniform magnetic field through the object, magnetic field gradients for imaging a portion of the object and an RF excitation field for evoking NMR response signals from the object; a computer for controlling the operation of the MRI system; a motion compensation module for generating a plurality of navigator waveforms for evoking a corresponding plurality of navigator echoes from the portion of the object while the object is being imaged, and processing the plurality of navigator echoes by determining a subset of similar navigator echoes and removing rigid-body translation from the NMR response signals associated with the subset of similar navigator echoes; and, interface circuitry for generating the magnetic gradient, RF and navigator waveforms and sampling the NMR response signals and the plurality of navigator echoes.

Claims

1. A method for acquiring MR image data for an object and performing motion compensation on the MR image data, the method comprising:

a) generating a uniform magnetic field through the object;

b) generating magnetic field gradients for imaging a portion of the object and an RF excitation field for evoking NMR response signals from the object;

c) generating a plurality of navigator waveforms for evoking a corresponding plurality of navigator echoes from the portion of the object while the object is being imaged;

d) sampling the NMR response signals and the plurality of navigator echoes; and

,

e) processing the plurality of navigator echoes by determining a subset of similar navigator echoes according to a similarity metric and removing rigid-body translations from the sampled NMR response signals associated with the subset of similar navigator echoes; and

f) displaying MR images generated based on the motion compensated MR image data.

2. The method of claim 1, wherein (e) further includes:

g) generating a plurality of navigator projections from the plurality of navigator echoes;

h) selecting a reference navigator projection from the plurality of navigator projections;

i) calculating a plurality of similarity values according to the similarity metric for the plurality of navigator projections with respect to the reference navigator projection; and

;

j) selecting the subset of similar navigator echoes from the plurality of navigator projections having the highest similarity values.

3. The method of claim 2, wherein (h) includes calculating the similarity values within a subset of the navigator projections that correspond to a region of interest in the portion of the object being imaged.

4. The method of claim 2, wherein the method comprises acquiring navigator echoes until a sufficiency criterion is satisfied.

5. The method of claim 4, wherein the method includes defining the sufficiency criterion so that the selected navigator projections differ at most by noise and rigid-body translation.

6. The method of claim 4, wherein the similarity metric is the correlation coefficient, and the method includes defining the sufficiency criterion so that the standard deviation of the calculated correlation coefficient values under a Fisher Transformation is less than the inverse of the square root of the number of pixels in a given navigator reference projection.

7. The method of claim 4, wherein in (d) sampling of the NMR response signals includes repeatedly only sampling k-space data for which corresponding navigator echoes have not yet met the sufficiency criterion.

8. The method of claim 1, wherein (e) further includes calculating a rigid-body translation for the similar navigator echoes in the selected subset and applying a linear phase correction based on the translation to the corresponding NMR response signals.

9. The method of claim 1, wherein (c) includes quasi-periodically interspersing the navigator waveforms in the magnetic field gradients and the RF excitation field.

10. The method of claim 1, wherein (c) includes generating magnetic field gradients associated with the navigator waveforms for providing a linear k-space sampling trajectory through k-space origin for sampling a given navigator echo.

11. The method of claim 1, wherein (c) includes generating the magnetic field gradients associated with the navigator waveforms for providing reference navigator projections in at least two dimensions and computing a multi-dimensional similarity metric to find navigator echoes that are similar in the at least two dimensions.

12. The method of claim 1, wherein the method comprises basing the similarity metric on one of correlation coefficients, least squares, cross-correlation, and mutual information.

13. An MRI system for acquiring MR image data for an object and performing motion compensation on the MR image data, the MRI system comprising:

a) an MRI device for generating a uniform magnetic field through the object, magnetic field gradients for imaging a portion of the object and an RF excitation field for evoking NMR response signals from the object;

b) a computer for controlling the operation of the MRI system;

c) a motion compensation module for generating a plurality of navigator waveforms for evoking a corresponding plurality of navigator echoes from the portion of the object that is being imaged, and processing the plurality of navigator echoes by determining a subset of similar navigator echoes and removing rigid-body translation from the NMR response signals associated with the subset of similar navigator echoes; and

,

d) interface circuitry for generating waveforms in response to instructions received from the computer and the motion compensation module and sending the waveforms to the MRI device for producing the magnetic field gradients, the RF excitation field and the navigator waveforms, the interface circuitry further being configured for sampling the NMR response signals and the plurality of navigator echoes.

14. The system of claim 13, wherein the motion compensation module generates a plurality of navigator projections from the plurality of navigator echoes, selects a reference navigator projection from the plurality of navigator projections, calculates a plurality of similarity values according to a similarity metric for the plurality of navigator projections with respect to the reference navigator projection, and selects the subset of similar navigator echoes from the plurality of navigator projections having the highest similarity values.

15. The system of claim 14, wherein the motion compensation module further calculates a rigid-body translation for the similar navigator echoes in the selected subset and applies a linear phase correction based on the displacement to the corresponding NMR response signals.

16. The system of claim 14, wherein the motion compensation module calculates the similarity values within a subset of the navigator projections that correspond to a region of interest in the portion of the object being imaged.

17. The system of claim 14, wherein the interface circuitry is configured to acquire navigator echoes until a sufficiency criterion is satisfied.

18. The system of claim 17, wherein the sufficiency criterion is defined so that the selected navigator projections differ at most by noise and rigid-body translation.

19. The system of claim 17, wherein the sufficiency criterion is defined so that the standard deviation of the calculated correlation coefficient values under a Fisher Transformation is less than the inverse of the square root of the number of pixels in a given navigator reference projection.

20. The system of claim 13, wherein the motion compensation module and interface circuitry quasi-periodically intersperses the navigator waveforms in the magnetic field gradients and the RF excitation field.

21. The system of claim 13, wherein the motion compensation module and interface circuitry in conjunction with the MRI device generate magnetic field gradients associated with the navigator waveforms for providing a linear k-space sampling trajectory through k-space origin for sampling a given navigator echo.

22. The system of claim 13, wherein the motion compensation module and interface circuitry in conjunction with the MRI device generate magnetic field gradients associated with the navigator waveforms for providing reference navigator projections in at least two dimensions and computing a multi-dimensional similarity metric to find navigator echoes that are similar in the at least two dimensions.

23. The system of claim 13, wherein the similarity metric is based on one of correlation coefficients, least squares, cross-correlation, and mutual information.

24. A method for performing motion compensation on MR image data, the MR image data including NMR response signals and corresponding navigator echoes, the method comprising:

a) selecting a similarity metric;

b) applying the similarity metric to the navigator echoes to determine a subset of similar navigator echoes; and

c) removing rigid-body translations from the NMR response signals associated with the subset of similar navigator echoes; and

d) displaying MR images generated based on the motion compensated MR image data.

25. The method of claim 24, wherein (b) further comprises:

e) generating navigator projections from the navigator echoes;

f) selecting a reference navigator projection from the navigator projections;

g) calculating a plurality of similarity values according to the similarity metric for the navigator projections with respect to the reference navigator projection; and

h) selecting the subset of similar navigator echoes from the navigator projections having the highest similarity values.

26. The method of claim 25, wherein (c) further includes calculating a rigid-body translation for the similar navigator echoes in the selected subset and applying a linear phase correction based on the translation to the corresponding NMR response signals.

27. The method of claim 25, wherein (f) includes calculating the similarity values within a subset of the navigator projections that correspond to a region of interest in the MR image data.

28. A computer program product comprising a computer readable medium embodying a program code means executable by a processor for carrying out a method for performing motion compensation on MR image data, the MR image data including NMR response signals and corresponding navigator echoes, the method comprising:

a) selecting a similarity metric;

b) applying the similarity metric to the navigator echoes to determine a subset of similar navigator echoes;

c) removing rigid-body translations from the NMR response signals associated with the subset of similar navigator echoes; and

d) displaying MR images generated based on the motion compensated MR image data.