Compositions for alleviating inflammation and oxidative stress in a mammal
First Claim
1. A composition comprising:
- (a) at least about 150 milligrams Bacopa monniera extract, wherein said Bacopa monniera extract is comprised of 45 percent bacosides;
at least about 225 milligrams silybum marianum (milk thistle) extract, wherein said milk thistle extract is comprised of between about 70 percent and about 80 percent silymarin;
at least about 150 mg Withania somnifera (ashwagandha) powder;
at least about 75 milligrams Camellia sinensis (green tea extract);
wherein said green tea extract is comprised of 98 percent polyphenols;
said polyphenols comprised of 45 percent (−
)-epigallocatechin gallate;
at least about 75 milligrams Curcuma longa (turmeric) extract;
wherein said turmeric extract is comprised of 95 percent curcumin;
wherein the composition increases the enzyme activity level of at least one antioxidant enzyme selected from the group consisting of;
superoxide dismutase and catalase and decreases the plasma concentration level of thiobarbituric acid reactive chemical species, when administered in an effective amount to a mammalian subject in need thereof.
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Abstract
An antioxidant-promoting composition that increases antioxidant defense potential in a subject is disclosed comprising Bacopa monniera extract; milk thistle extract, ashwagandha powder, green tea extract, Gotu kola powder, Ginko biloba leaf extract; Aloe vera powder; turmeric extract; and N-acetyl cysteine. The antioxidant-promoting composition of the invention safely induces cellular antioxidant potential to achieve an overall net decrease in oxidative stress without the undesirable side-effects associated with the individual components of the antioxidant-promoting composition. Also disclosed is a method for reducing the undesirable side-effects of free radicals in a subject by administering to a subject in need of such antioxidants an effective amount of antioxidant-promoting composition of the invention.
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Citations
3 Claims
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1. A composition comprising:
- (a) at least about 150 milligrams Bacopa monniera extract, wherein said Bacopa monniera extract is comprised of 45 percent bacosides;
at least about 225 milligrams silybum marianum (milk thistle) extract, wherein said milk thistle extract is comprised of between about 70 percent and about 80 percent silymarin;
at least about 150 mg Withania somnifera (ashwagandha) powder;
at least about 75 milligrams Camellia sinensis (green tea extract);
wherein said green tea extract is comprised of 98 percent polyphenols;
said polyphenols comprised of 45 percent (−
)-epigallocatechin gallate;
at least about 75 milligrams Curcuma longa (turmeric) extract;
wherein said turmeric extract is comprised of 95 percent curcumin;
wherein the composition increases the enzyme activity level of at least one antioxidant enzyme selected from the group consisting of;
superoxide dismutase and catalase and decreases the plasma concentration level of thiobarbituric acid reactive chemical species, when administered in an effective amount to a mammalian subject in need thereof. - View Dependent Claims (2, 3)
- (a) at least about 150 milligrams Bacopa monniera extract, wherein said Bacopa monniera extract is comprised of 45 percent bacosides;
Specification