Implanted surgical drain with multiple sensing elements for monitoring internal tissue condition

• US 7,244,251 B2
• Filed: 02/09/2004
• Issued: 07/17/2007
• Est. Priority Date: 02/07/2003
• Status: Expired due to Fees

• Current Assignee: Photosonics Medical, Inc.
• Original Assignee: Alfred E MANN Institute For Biomedical Engineering At The University of Southern California
• Inventors: Shehada, Ramez Emile Necola, Jabbour, Nicolas
• Primary Examiner(s): Zalukaeva; Tatyana
• Assistant Examiner(s): KAHN, LAURA HILL
• Application Number:
  US10/776,022
• Publication Number:
  US 20040254432A1
• Time in Patent Office: 1,254 Days
• Field of Search: 604540-541, 600300-301, 600/573, 600/302, 600/324, 600/329, 607/115, 607/149
• US Class Current: 604/541
• CPC Class Codes: A61B 2562/228 Sensors with optical connectors
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/0071 by measuring fluorescence emission
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/0084 for introduction into the body, e.g. by catheters A61B5/1459 takes precedence
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/036 by means introduced into body tracts A61B5/032 and A61B5/035 take precedence
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/14503 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/412 Detecting or monitoring sepsis
• CPC Class Codes: A61B 5/413 Monitoring transplanted tissue or organ, e.g. for possible rejection reactions after a transplant
• CPC Class Codes: A61B 5/42 Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems A61B1/00, A61B5/4857, A61B5/486, A61B5/4866, A61B5/4869 take precedence
• CPC Class Codes: A61B 5/6882 Anchoring means
• CPC Class Codes: A61B 5/6885 Monitoring or controlling sensor contact pressure
• CPC Class Codes: A61M 1/918 for multiple suction locations
• CPC Class Codes: A61M 1/95 with sensors for exudate composition
• CPC Class Codes: A61M 27/002 Implant devices for drainage of body fluids from one part of the body to another intraocular A61F9/00781; middle ear A61F11/202

Abstract

The present invention is directed to devices and methods of using a surgical drain, and more particularly to a surgical drain having at least one sensor for monitoring and/or recording the condition of the anatomical site or fluid emitted from the site where the surgical drain is placed. The invention may also include modifications of the surgical drain to improve stabilization or immobilization in the proximity of the anatomical site to be monitored.

Claims

1. A surgical drain for sensing a physiological property of at least one tissue and draining fluid from a body comprising:

a) an elongated conduit configured to be implanted in a patient'"'"'s body and rest against a first tissue and a second tissue within the body to drain fluid from the patient'"'"'s body, wherein the elongated conduit comprises a drain portion having openings spaced along substantially the length of the drain portion, wherein the surgical drain is not configured to penetrate either the first or second tissues;

b) a first sensing element configured to sense a physiological property of the first tissue adjacent to a first location of the elongated conduit; and

c) a second sensing element configured to sense the same physiological property of the second tissue adjacent to a second location of the elongated conduit different than the first location.

2. The surgical drain of claim 1, wherein the physiological property is selected from the group comprising:

temperature, oxygenation, perfusion, pH, NADH levels, biochemical composition, drug concentrations, turgidity or pressure.

3. The surgical drain of claim 1, further including at least one transmitting element configured to deliver energy to the first tissue and the second tissue located proximate to the first and second locations.

4. The surgical drain of claim 1, comprising a third sensing element configured to sense a second physiological property of tissue proximate to the conduit that is different from the physiological property sensed by the first and second sensing elements.

5. The surgical drain of claim 1, wherein at least portions of the first and second sensing elements are embedded within the conduit behind material that is optically transparent.

6. The surgical drain of claim 1, further including a processing system in communication with the first and second sensing elements configured to compare a difference between the physiological property sensed by the first and second sensing elements.

7. The surgical drain of claim 6, wherein the sensing elements sense oxygenation and wherein the processing system is configured to compare the difference between the oxygenation sensed by the first and second sensing elements.

8. The surgical drain of claim 6, wherein said processing system further including a display configured to depict data corresponding to the physiological property sensed by the first or second sensing elements.

9. The surgical drain of claim 1, wherein the conduit further comprises a third sensing element configured to sense the same physiological property of tissue adjacent to a third location of the elongated conduit different from the first and second locations;

and a fourth sensing element configured to sense the same physiological property of tissue adjacent to a fourth location of the elongated conduit different from the first, second and third locations.

10. The surgical drain of claim 9, further including a processing system configured to compare a difference between the physiological property sensed by the first, the second, the third and the fourth sensing elements.

11. The surgical drain of claim 1, wherein the first and second sensing elements include optical fibers.

12. The surgical drain of claim 1, wherein the first sensing element includes a component that is affixed to the conduit.

13. The surgical drain of claim 12, wherein the component is embedded in the conduit.

14. The surgical drain of claim 12, wherein the component includes a sensor.

15. The surgical drain of claim 12, wherein the component includes an optical fiber.

16. The surgical drain of claim 1, wherein the first tissue and the second tissue are part of the same organ.

17. The surgical drain of claim 1, wherein the first tissue and the second tissue are not part of the same organ.

18. The surgical drain of claim 1, wherein the first sensing element and the second sensing element are located on the same surface of the elongated conduit.

19. The surgical drain of claim 1, wherein the first sensing element and the second sensing element are located on substantially opposing surfaces of the elongated conduit.

20. A surgical drain for sensing a physiological property of at least one tissue and draining fluid from a body comprising:

a) an elongated conduit configured to be implanted in a patient'"'"'s body in proximity to an organ at a first location and to a tissue that is not part of the organ at a second location that is different from the first location, the elongated conduit having a drain portion with openings spaced along substantially its length and configured to drain fluid from the patient'"'"'s body in the vicinity of the organ and the tissue, wherein the surgical drain is not configured to penetrate either the first or second tissues;

b) a first sensing element coupled to the elongated conduit and configured to sense a physiological property of the organ; and

c) a second sensing element coupled to the elongated conduit and configured to separately sense the same physiological property of the tissue.

21. The surgical drain of claim 20, further comprising a processing system configured to compare the physiological property sensed by the first sensing element with the physiological property sensed by the second sensing element.