Diagnosis of peripheral vascular disease using oxygen saturation

• US 7,247,142 B1
• Filed: 05/03/2004
• Issued: 07/24/2007
• Est. Priority Date: 05/05/2003
• Status: Active Grant

• Current Assignee: Viopfix, Inc.
• Original Assignee: ViOptix, Inc.
• Inventors: O'Keefe, William, Christenson, Linda, Elmandjra, Mohamed, Bush, Robin, Mao, Jian Min
• Primary Examiner(s): Nasser; Robert L.
• Application Number:
  US10/838,142
• Time in Patent Office: 1,177 Days
• Field of Search: None
• US Class Current: 600/481
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/14551 for measuring blood gases

Abstract

Techniques for diagnosing peripheral vascular disease using oxygen saturation are provided. Changes in oxygen saturation in tissue during recovery from induced ischemia are measured. The changes are then utilized to diagnose whether a patient has peripheral vascular disease.

Claims

1. A method of diagnosing peripheral vascular disease, comprising:

measuring oxygen saturation in tissue of a patient during recovery from ischemia;

analyzing the oxygen saturation in the tissue during the recovery; and

diagnosing the patient as having peripheral vascular disease according to changes in the oxygen saturation in the tissue during the recovery.

2. The method of claim 1, wherein the analyzing the oxygen saturation comprises calculating a rate of change of oxygen saturation during the recovery.

3. The method of claim 2, wherein the rate of change is calculated at a mid-point of the recovery.

4. The method of claim 2, wherein the diagnosing the patient comprises determining if the rate of change crosses a threshold.

5. The method of claim 1, wherein the analyzing the oxygen saturation comprises calculating a time for oxygen saturation to recover a specified percentage during the recovery.

6. The method of claim 5, wherein the specified percentage is approximately 80%.

7. The method of claim 5, wherein the diagnosing the patient comprises determining if the time for oxygen saturation to recover crosses a threshold.

8. The method of claim 1, wherein the analyzing the oxygen saturation comprises:

calculating a rate of change of oxygen saturation during the recovery; and

calculating a time for oxygen saturation to recover a specified percentage during the recovery.

9. The method of claim 8, wherein the diagnosing the patient comprises determining if the rate of change and the time for oxygen saturation to recover cross thresholds.

10. An apparatus for diagnosing peripheral vascular disease, comprising:

a device to cause ischemia in tissue

a probe that measures oxygen saturation in the tissue of a patient during recovery from induced ischemia;

a computer, coupled to the probe, that analyzes the oxygen saturation in the tissue during the recovery and diagnoses the patient as having peripheral vascular disease according to the oxygen saturation in the tissue during the recovery.

11. A method of diagnosing peripheral vascular disease, comprising:

measuring oxygen saturation in tissue of a patient during recovery from ischemia;

calculating a rate of change of oxygen saturation during the recovery; and

diagnosing the patient as having peripheral vascular disease if the rate of change crosses a threshold.

12. The method of claim 11, wherein the rate of change is calculated at a mid-point of the recovery.

13. An apparatus for diagnosing peripheral vascular disease, comprising:

a probe that measures oxygen saturation in tissue of a patient during recovery from ischemia;

a computer, coupled to the probe, that calculates a rate of change of oxygen saturation during the recovery and diagnoses the patient as having peripheral vascular disease if the rate of change crosses a threshold.

14. A method of diagnosing peripheral vascular disease, comprising:

measuring oxygen saturation in tissue of a patient during recovery from ischemia;

calculating a time for oxygen saturation to recover a specified percentage during the recovery; and

diagnosing the patient as having peripheral vascular disease if the time for oxygen saturation to recover crosses a threshold.

15. The method of claim 14, wherein the specified percentage is approximately 80%.

16. An apparatus for diagnosing peripheral vascular disease, comprising:

a probe that measures oxygen saturation in tissue of a patient during recovery from ischemia;

a computer, coupled to the probe, that calculates a time for oxygen saturation to recover a specified percentage during the recovery and diagnoses the patient as having peripheral vascular disease if the time for oxygen saturation to recover crosses a threshold.