Implantable heart stimulator with electrodes for an infection control current

• US 7,248,927 B2
• Filed: 02/26/2002
• Issued: 07/24/2007
• Est. Priority Date: 02/27/2001
• Status: Expired due to Fees

• Current Assignee: St. Jude Medical AB (Abbott Laboratories Incorporated)
• Original Assignee: St. Jude Medical AB (Abbott Laboratories Incorporated)
• Inventors: Obel, Martin, Micski, Eva, Eckerdal, Johan
• Primary Examiner(s): Evanisko; George R.
• Assistant Examiner(s): KAHELIN, MICHAEL WILLIAM
• Application Number:
  US10/468,587
• Publication Number:
  US 20040098054A1
• Time in Patent Office: 1,974 Days
• Field of Search: 607 4- 5, 607/9, 607/37, 607/63, 607/36, 607/3
• US Class Current: 607/36
• CPC Class Codes: A61N 1/056 Transvascular endocardial electrode systems
• CPC Class Codes: A61N 1/205 for promoting a biological process
• CPC Class Codes: A61N 1/375 Constructional arrangements, e.g. casings
• CPC Class Codes: A61N 1/37512 Pacemakers

Abstract

An implantable heart stimulator has an electrically conductive housing containing a pulse generator, with an electrode lead connected to the housing. The electrode lead has a proximal portion extending substantially from the housing to a location, after implantation, which is beyond the entry of the lead into the venous system and before the entry of the lead into the superior vena cava. A current source supplies an infection control current between the housing and an electrically conductive surface on the exterior of the proximal portion of the electrode lead, for counteracting bacterial growth. The housing may have a header to which the electrode lead is connected, in which case the header is provided with an electrically conductive surface as well, which can serve as an electrode for the infection control current.

Claims

1. An implantable heart stimulator comprising:

a pulse generator and an electrode lead connected thereto for delivering electrical stimulation pulses to a heart of a patient, said pulse generator having an electrically conductive housing, said housing comprising a connector header in which said electrode lead is mechanically and electrically connected;

said electrode lead having a proximal portion which, after implantation of said electrode lead, is configured to extend substantially from the housing to a location situated beyond entry of the electrode lead into the venous system and before entry of the electrode lead into the superior vena cava, said proximal portion having an exterior with an electrically conductive surface; and

a current source for supplying an infection control current between said housing and said electrically conductive surface of said proximal portion of said electrode lead for counteracting bacterial growth at least on an exterior of said housing, said connector header having an exterior surface that is entirely electrically conductive and is in a flow path of said infection control current.

2. An implantable heart stimulator as claimed in claim 1 wherein at least one of said electrically conductive surface on the exterior of said proximal portion of said electrode lead and said electrically conductive surface on said exterior of said connector header is formed by an electrically conducting polymer.

3. An implantable heart stimulator as claimed in claim 1 wherein at least one of said electrically conductive surface on the exterior of said proximal portion of said electrode lead and said electrically conductive surface on said exterior of said connector header is formed by an ion implantation.

4. An implantable heart stimulator as claimed in claim 1 wherein at least one of said electrically conductive surface on the exterior of said proximal portion of said electrode lead and said electrically conductive surface on said exterior of said connector header is formed by ion beam assisted deposition.

5. An implantable heart stimulator as claimed in claim 1 wherein at least one of said electrically conductive surface on the exterior of said proximal portion of said electrode lead and said electrically conductive surface on said exterior of said connector header is formed by a coating process selected from the group consisting of vapor deposition and sputtering.

6. An implantable heart stimulator as claimed in claim 1 wherein said electrically conductive surface on said exterior of said connector header is electrically isolated from said electrically conductive surface on said exterior of said proximal portion of said electrode lead.

7. An implantable heart stimulator as claimed in claim 1 wherein said conductive surface at the exterior of said proximal portion of said electrode lead is formed by an electrically conductive coil.

8. An implantable heart stimulator as claimed in claim 1 wherein said housing has an exterior coated with a metal selected from the group consisting of platinum, palladium, indium, platinum alloys, palladium alloys and indium alloys.

9. An implantable heart stimulator as claimed in claim 1 wherein said electrically conductive surface at said exterior of said proximal portion of said electrode lead is electrically isolated from said housing.

10. An implantable heart stimulator as claimed in claim 1 wherein said current source comprises a battery contained in said housing, which also supplies power to said pulse generator.

11. An implantable heart stimulator comprising:

a pulse generator and an electrode lead connected thereto for delivering electrical stimulation pulses to a heart of a patient, said pulse generator having an electrically conductive housing;

said electrode lead having a proximal portion which, after implantation of said electrode lead, is configured to extend substantially from the housing to a location situated beyond entry of the electrode lead into the venous system and before entry of the electrode lead into the superior vena cava, said proximal portion having an exterior with an electrically conductive surface; and

an extracorporeal current source, and an inductive coupling arrangement to inductively couple said extracorporeal current source with said housing and said electrically conductive surface on said exterior of said proximal portion of said electrode lead supplying an infection control current between said housing and said electrically conductive surface of said proximal portion of said electrode lead for counteracting bacterial growth at least on an exterior of said housing.

12. An implantable heart stimulator as claimed in claim 11 wherein said inductive coupling arrangement comprises a thin inductive coil attached at an outer surface of said housing, and electrically connected to said housing and to said electrically conductive surface on said exterior of said proximal portion of said electrode lead.

13. An implantable heart stimulator as claimed in claim 11 wherein said inductive coupling arrangement comprises a thin inductive coil disposed inside of said housing, and electrically connected to said housing and to said electrically conductive surface on said exterior of said proximal portion of said electrode lead.

14. An implantable heart stimulator as claimed in claim 11 wherein said inductive coupling arrangement includes a diode for producing a d.c. current as said infection control current.

15. An implantable heart stimulator as claimed in claim 11 wherein said inductive coupling arrangement includes transcutaneous electrodes connected between said extracorporeal current source and said housing and said electrically conductive surface on said exterior of said proximal portion of said electrode lead.

16. An implantable heart stimulator comprising:

a pulse generator which generates electrical stimulation pulses;

an electrically conductive housing containing said pulse generator and having a connector header;

an electrode lead mechanically and electrically connected in said header, and thereby connected to said pulse generator, for delivering said stimulation pulses to a heart of a patient;

said header having an exterior surface that is entirely electrically conductive;

said electrode lead having a proximal portion extending substantially from said housing to a location, after implantation of said electrode lead, adapted to be situated beyond entry into the venous system and before entry into the superior vena cava, said proximal portion having an exterior with an electrically conductive surface thereon;

a current source which supplies an infection control current in a flowpath including at least two of said housing, said electrically conductive surface on said exterior of said header and said electrically conductive surface on said exterior of said proximal portion of said electrode lead, to counteract bacterial growth at least one an exterior of said housing; and

at least one of said electrically conductive surface on the exterior of said proximal portion of said electrode lead and said exterior electrically conductive surface of said connector header being formed by an electrically conducting polymer.

17. An implantable heart stimulator as claimed in claim 16 wherein said conductive surface at the exterior of said proximal portion of said electrode lead is formed by an electrically conductive coil.

18. An implantable heart stimulator as claimed in claim 16 wherein said housing has an exterior coated with a metal selected from the group consisting of platinum, palladium, indium, platinum alloys, palladium alloys and indium alloys.

19. An implantable heart stimulator as claimed in claim 16 wherein said electrically conductive surface at said exterior of said proximal portion of said electrode lead is electrically isolated from said housing.

20. An implantable heart stimulator as claimed in claim 16 wherein said current source comprises a battery contained in said housing, which also supplies power to said pulse generator.

21. An implantable heart stimulator as claimed in claim 16 wherein said current source is an extracorporeal current source, and wherein said apparatus comprises an inductive coupling arrangement to inductively couple said extracorporeal current source with said housing and said electrically conductive surface on said exterior of said proximal portion of said electrode lead.

22. An implantable heart stimulator as claimed in claim 21 wherein said inductive coupling arrangement comprises a thin inductive coil attached at an outer surface of said housing, and electrically connected to said housing and to said electrically conductive surface on said exterior of said proximal portion of said electrode lead.

23. An implantable heart stimulator as claimed in claim 21 wherein said inductive coupling arrangement comprises a thin inductive coil disposed inside of said housing, and electrically connected to said housing and to said electrically conductive surface on said exterior of said proximal portion of said electrode lead.

24. An implantable heart stimulator as claimed in claim 21 wherein said inductive coupling arrangement includes a diode for producing a d.c. current as said infection control current.

25. An implantable heart stimulator as claimed in claim 21 wherein said inductive coupling arrangement includes transcutaneous electrodes connected between said extracorporeal current source and said housing and said electrically conductive surface on said exterior of said proximal portion of said electrode lead.

26. An implantable heart stimulator comprising:

a pulse generator which generates electrical stimulation pulses;

an electrically conductive housing containing said pulse generator and having a connector header;

an electrode lead mechanically and electrically connected in said header, and thereby connected to said pulse generator, for delivering said stimulation pulses to a heart of a patient;

said header having an exterior surface that is entirely electrically conductive surface;

said electrode lead having a proximal portion extending substantially from said housing to a location, after implantation of said electrode lead, adapted to be situated beyond entry into the venous system and before entry into the superior vena cava, said proximal portion having an exterior with an electrically conductive surface thereon;

a current source which supplies an infection control current in a flowpath including at least two of said housing, said electrically conductive surface on said exterior of said header and said electrically conductive surface on said exterior of said proximal portion of said electrode lead, to counteract bacterial growth at least one an exterior of said housing; and

at least one of said electrically conductive surface on the exterior of said proximal portion of said electrode lead and said exterior electrically conductive surface of said connector header being formed by an ion implantation.

27. An implantable heart stimulator comprising:

a pulse generator which generates electrical stimulation pulses;

an electrically conductive housing containing said pulse generator and having a connector header;

an electrode lead mechanically and electrically connected in said header, and thereby connected to said pulse generator, for delivering said stimulation pulses to a heart of a patient;

said header having an exterior surface that is entirely electrically conductive surface;

said electrode lead having a proximal portion extending substantially from said housing to a location, after implantation of said electrode lead, adapted to be situated beyond entry into the venous system and before entry into the superior vena cava, said proximal portion having an exterior with an electrically conductive surface thereon; and

a current source which supplies an infection control current in a flowpath including at least two of said housing, said electrically conductive surface on said exterior of said header and said electrically conductive surface on said exterior of said proximal portion of said electrode lead, to counteract bacterial growth at least one an exterior of said housing; and

at least one of said electrically conductive surface on the exterior of said proximal portion of said electrode lead and said exterior electrically conductive surface of said connector header being formed by ion beam assisted deposition.

28. An implantable heart stimulator comprising:

a pulse generator which generates electrical stimulation pulses;

an electrically conductive housing containing said pulse generator and having a connector header;

an electrode lead mechanically and electrically connected in said header, and thereby connected to said pulse generator, for delivering said stimulation pulses to a heart of a patient;

said header having an exterior surface that is entirely electrically conductive surface;

said electrode lead having a proximal portion extending substantially from said housing to a location, after implantation of said electrode lead, adapted to be situated beyond entry into the venous system and before entry into the superior vena cava, said proximal portion having an exterior with an electrically conductive surface thereon; and

a current source which supplies an infection control current in a flowpath including at least two of said housing, said exterior electrically conductive surface of said header and said electrically conductive surface on said exterior of said proximal portion of said electrode lead, to counteract bacterial growth at least one an exterior of said housing; and

at least one of said electrically conductive surface on the exterior of said proximal portion of said electrode lead and said exterior electrically conductive surface of said connector header being formed by a coating process selected from the group consisting of vapor deposition and sputtering.

29. An implantable heart stimulator comprising:

a pulse generator which generates electrical stimulation pulses;

an electrically conductive housing containing said pulse generator and having a connector header;

an electrode lead mechanically and electrically connected in said header, and thereby connected to said pulse generator, for delivering said stimulation pulses to a heart of a patient;

said header having an exterior surface that is entirely electrically conductive;

said electrode lead having a proximal portion extending substantially from said housing to a location, after implantation of said electrode lead, adapted to be situated beyond entry into the venous system and before entry into the superior vena cava, said proximal portion having an exterior with an electrically conductive surface thereon; and

a current source which supplies an infection control current in a flowpath including at least two of said housing, said exterior electrically conductive surface of said header and said electrically conductive surface on said exterior of said proximal portion of said electrode lead, to counteract bacterial growth at least one an exterior of said housing; and

said electrically conductive exterior surface of said connector header being electrically isolated from said electrically conductive surface on said exterior of said proximal portion of said electrode lead.