Mercaptophenyl naphthyl methane compounds and synthesis thereof
First Claim
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1. A mercaptophenyl naphthyl methane compound having the structural formula 1:
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Abstract
Novel mercaptophenyl naphthyl methane compounds, their pharmaceutically acceptable salts and compositions comprised thereof are useful for the prevention or treatment of various medical indications associated with estrogen dependent diseases or syndromes related to osteoporosis, bone loss, bone formation, cardiovascular disorders, neurodegenerative disorders, menopausal disorders, physiological disorders, diabetes disorders, prostatic carcinoma, cancer of breast, cancer of uterus, cancer of the cervix and cancer of the colon, threatened or habitual abortion, obesity, ovarian development or function, post-partum lactation and depression.
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49 Claims
- 1. A mercaptophenyl naphthyl methane compound having the structural formula 1:
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2. A mercaptophenyl naphthyl methane compound having the structural formula 1:
- 32. A pharmaceutical composition comprising a mercaptophenyl naphthyl methane compound having structural formula 1
- 42. A mercaptophenyl maphthyl methane compound having the structural formula 1:
- 47. A pharmaceutical composition comprising a mercaptophenyl naphthyl methane compound having the structural formula 1:
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