IL-23p40 specific immunoglobulin derived proteins
First Claim
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1. An isolated polypeptide comprising the murine IL-23 protein, wherein the Murineseg 2 of murine IL-23p40 is replaced by the amino acid sequence of Seg 2 of human IL-23p40.
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Abstract
An anti-IL-23 specific human Ig derived protein is useful in therapeutic and diagnostic compositions, methods and devices. The anti-IL-23 Ig derived protein preferably includes one or more of the Seg 1, Seg 2, and Seg 3 epitopes of the p40 subunit of IL-23.
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1 Claim
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1. An isolated polypeptide comprising the murine IL-23 protein, wherein the Murineseg 2 of murine IL-23p40 is replaced by the amino acid sequence of Seg 2 of human IL-23p40.
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