Apparatus for determination of stroke volume using the brachial artery
First Claim
1. An apparatus for determining stroke volume by bioimpedance from a patient'"'"'s brachial artery, comprising:
- two or more spaced apart alternating current flow electrodes positioned on the patient'"'"'s arm proximate the brachial artery;
two or more spaced apart voltage sensing electrodes positioned on the patient'"'"'s arm proximate the brachial artery, the voltage sensing electrodes being positioned between the alternating current flow electrodes;
an alternating current source electrically connected to the alternating current flow electrodes,a voltmeter electrically connected to the voltage sensing electrodes;
a data input device;
a processing unit in communication with the data input device, the alternating current source, alternating current flow electrodes, the voltmeter, and voltage sensing electrodes, the processing unit capable of using data from the data input device and voltage sensing electrodes to calculate the stroke volume of the patient;
wherein the processing unit uses the equation;
SV(brachium)=Vc(brachium)·
√
[(dZ/dtmax)/Z0](brachium)·
Tlve to determine stroke volume;
wherein Vc(brachium)is determined by a calibration factor, Vc(cal), using the equation;
Vc(brachium)=Vc(cal)=(Vc(thorax)·
√
[(dZ/dtmax)/Z0](thorax))/(√
[(dZ/dtmax)/Z0](brachium)),and wherein the stroke volume equation is;
SV(brachium)=Vc(cal)·
√
[(dZ/dtmax)/Z0](brachium)·
Tlve.
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Abstract
Provided herein are methods and apparatus for stroke volume determination by bioimpedance from a patient'"'"'s upper arm, or brachium, utilizing pulsations of the brachial artery contained therein. The apparatus includes two or more spaced apart alternating current flow electrodes positioned on the patient'"'"'s arm proximate the brachial artery and two or more spaced apart voltage sensing electrodes positioned on the patient'"'"'s arm proximate the brachial artery. The voltage sensing electrodes are positioned between the alternating current flow electrodes on the arm. An alternating current source is electrically connected to the alternating current flow electrodes and a voltmeter electrically is connected to the voltage sensing electrodes. A data input device is provided along with a processing unit in communication with the data input device, the alternating current source, alternating current flow electrodes, the voltmeter, and voltage sensing electrodes. The processing unit is capable of using data from the data input device and voltage sensing electrodes to calculate the stroke volume of the patient.
79 Citations
8 Claims
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1. An apparatus for determining stroke volume by bioimpedance from a patient'"'"'s brachial artery, comprising:
-
two or more spaced apart alternating current flow electrodes positioned on the patient'"'"'s arm proximate the brachial artery; two or more spaced apart voltage sensing electrodes positioned on the patient'"'"'s arm proximate the brachial artery, the voltage sensing electrodes being positioned between the alternating current flow electrodes; an alternating current source electrically connected to the alternating current flow electrodes, a voltmeter electrically connected to the voltage sensing electrodes; a data input device; a processing unit in communication with the data input device, the alternating current source, alternating current flow electrodes, the voltmeter, and voltage sensing electrodes, the processing unit capable of using data from the data input device and voltage sensing electrodes to calculate the stroke volume of the patient; wherein the processing unit uses the equation; SV(brachium)=Vc(brachium)·
√
[(dZ/dtmax)/Z0](brachium)·
Tlve to determine stroke volume;wherein Vc(brachium)is determined by a calibration factor, Vc(cal), using the equation; Vc(brachium)=Vc(cal)=(Vc(thorax)·
√
[(dZ/dtmax)/Z0](thorax))/(√
[(dZ/dtmax)/Z0](brachium)),and wherein the stroke volume equation is;
SV(brachium)=Vc(cal)·
√
[(dZ/dtmax)/Z0](brachium)·
Tlve.
-
-
2. An apparatus for determining stroke volume by bioimpedance from a patient'"'"'s brachial artery, comprising:
-
two or more spaced apart alternating current flow electrodes positioned on the patient'"'"'s arm proximate the brachial artery; two or more spaced apart voltage sensing electrodes positioned on the patient'"'"'s arm proximate the brachial artery, the voltage sensing electrodes being positioned between the alternating current flow electrodes; an alternating current source electrically connected to the alternating current flow electrodes, a voltmeter electrically connected to the voltage sensing electrodes; a data input device; and a processing unit in communication with the data input device, the alternating current source, alternating current flow electrodes, the voltmeter, and voltage sensing electrodes, the processing unit capable of using data from the data input device and voltage sensing electrodes to determine a peak rate of change of a measured cardiogenically induced transbrachial impedance variation and a left ventricular ejection time and to calculate the stroke volume of the patient therefrom; wherein the processing unit uses the equation;
SV(brachium)=Vc(brachium)·
√
[(dZ/dtmax)/Z0](brachium)·
Tlve to determine stroke volume,and wherein Tlve is obtained from a dZ/dt waveform. - View Dependent Claims (3, 4)
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5. An apparatus for determining stroke volume by bioimpedance from a patient'"'"'s brachial artery, comprising:
-
two or more spaced apart alternating current flow electrodes positionable on the patient'"'"'s arm proximate the brachial artery; two or more spaced apart voltage sensing electrodes positionable on the patient'"'"'s arm proximate the brachial artery, the voltage sensing electrodes being positionable between the alternating current flow electrodes; an alternating current source electrically connected to the alternating current flow electrodes, a voltmeter electrically connected to the voltage sensing electrodes; a data input device; and a processing unit in communication with the data input device, the alternating current source, the alternating current flow electrodes, the voltmeter, and the voltage sensing electrodes, wherein the processing unit is capable of using data from the data input device and a voltage sensed by the voltage sensing electrodes to calculate the stroke volume of the patient; wherein the processing unit uses the equation; SV(brachium)=Vc(brachium)·
√
[(dZ/dtmax)/Z0](brachium)·
Tlve to calculate the stroke volume, where SV(brachium) is the stroke volume, V(brachium) is a volume of electrically participating brachial tissue, dZ/dtmax is a peak rate of change of a measured cardiogenically induced transbrachial impedance variation, Z0 is a quasi-static transbrachial base impedance, and Tlve is a left ventricular ejection time; and
wherein Vc(brachium) is determined by a calibration factor, Vc(cal), using the equation;
Vc(brachium)=Vc(cal)=(Vc(thorax)·
√
[(dZ/dtmax)/Z0](thorax))/(√
[(dZ/dtmax)/Z0](brachium)),and wherein the stroke volume equation is;
SV(brachium)=Vc(cal)·
√
[(dZ/dtmax)/Z0](brachium)·
Tlve.
-
-
6. An apparatus for determining stroke volume by bioimpedance from a patient'"'"'s brachial artery, comprising:
-
two or more spaced apart alternating current flow electrodes positionable on the patient'"'"'s arm proximate the brachial artery; two or more spaced apart voltage sensing electrodes positionable on the patient'"'"'s arm proximate the brachial artery, the voltage sensing electrodes being positionable between the alternating current flow electrodes; an alternating current source electrically connected to the alternating current flow electrodes, a voltmeter electrically connected to the voltage sensing electrodes; a data input device; and a processing unit in communication with the data input device, the alternating current source, the alternating current flow electrodes, the voltmeter, and the voltage sensing electrodes, wherein the processing unit is capable of using data from the data input device and a voltage sensed by the voltage sensing electrodes to determine a peak rate of change of a measured cardiogenically induced transbrachial impedance variation and a left ventricular ejection time and to calculate the stroke volume of the patient therefrom; wherein the processing unit uses the equation;
SV(brachium)=Vc(brachium)·
√
[(dZ/dtmax)/Z0](brachium)·
Tlveto calculate the stroke volume, where SV(brachium) is the stroke volume, Vc(brachium) is a volume of electrically participating brachial tissue, dZ/dtmax is a peak rate of change of a measured cardiogenically induced transbrachial impedance variation, Z0 is a quasi-static transbrachial base impedance, and Tlve is a left ventricular ejection time, and wherein Tlve is obtained from a dZ/dt waveform. - View Dependent Claims (7, 8)
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Specification