System and method for controlling rate of heat exchange with patient

• US 7,278,984 B2
• Filed: 12/31/2002
• Issued: 10/09/2007
• Est. Priority Date: 12/31/2002
• Status: Expired due to Term

• Current Assignee: Zoll Circulation Incorporated (Asahi Kasei Corporation)
• Original Assignee: Alsius Corporation
• Inventors: Whitebook, Mark Evan, Evans, Scott M., Noda, Wayne A., Balding, David P.
• Primary Examiner(s): WILLIAMS, CATHERINE SERKE
• Application Number:
  US10/334,414
• Publication Number:
  US 20040127851A1
• Time in Patent Office: 1,743 Days
• Field of Search: 604/113, 604/114, 604/27, 604/28, 604/43, 604/500, 137/340, 137/334, 137/341, 165177-184
• US Class Current: 604/113
• CPC Class Codes: A61F 2007/0054 with a closed fluid circuit, e.g. hot water
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61F 7/0085 Devices for generating hot or cold treatment fluids
• CPC Class Codes: A61F 7/12 Devices for heating or cooling internal body cavities

Abstract

A patient control system uses a patient-implanted catheter in thermal communication with a fluid bath via a circulating fluid circuit. A controller automatically controls the temperature of the fluid bath as required for selectively cooling or heating the patient in accordance with patient temperature measurements. The controller thermally decouples the catheter and patient from the fluid bath during changes in fluid bath temperatures in order to overcome the effects of system thermal mass.

Claims

1. A method for changing the temperature of the body of a patient using a thermal exchange device comprising:

transferring heat between the body of the patient and the thermal exchange device at a first heat transfer rate by implanting a catheter into the body of the patient and circulating a heat exchange fluid with a pump in a heat exchange relationship between the catheter and a fluid bath;

stopping the pump when a target temperature is reached and leaving the catheter in the patient;

slewing the fluid bath;

restarting the pump; and

transferring heat between the body of the patient and the thermal exchange device at a second heat transfer rate.

2. The method of claim 1, wherein stopping the pump when a target temperature is reached and leaving the catheter in the patient comprises reducing the circulation rate of the heat exchange fluid to a vanishingly low level.

3. The method of claim 2, further comprising:

determining the temperature of the patient relative to a predetermined range;

determining the temperature of the thermal exchange device; and

wherein stopping the pump when a target temperature is reached and leaving the catheter in the patient is performed when the temperature of the body of the patient is greater than the predetermined range but is less than the temperature of the thermal exchange device.

4. The method of claim 2, further comprising:

determining the temperature of the patient relative to a predetermined range;

determining the temperature of the thermal exchange device; and

stopping the pump when a target temperature is reached and leaving the catheter in the patient is performed when the temperature of the body of the patient is less than the predetermined range and is less than the temperature of the thermal exchange device.

5. The method of claim 2, further comprising:

determining the temperature of the patient relative to a predetermined target temperature; and

determining the temperature of the thermal exchange device, wherein reducing the circulation of heat exchange fluid is performed when the temperature of the body of the patient is greater than the predetermined target temperature but is less than the temperature of the thermal exchange device.

6. The method of claim 2, further comprising:

determining the temperature of the patient relative to a predetermined target temperature; and

determining the temperature of the thermal exchange device, wherein reducing the circulation of heat exchange fluid is performed when the temperature of the body of the patient is less than the predetermined target temperature but is greater than the temperature of the thermal exchange device.

7. The method of claim 2, further comprising:

determining the temperature of the patient relative to a predetermined range; and

determining the temperature of the thermal exchange device, wherein reducing the circulation of heat exchange fluid is performed when the temperature of the body of the patient is less than the predetermined range but is greater than the temperature of the thermal exchange device.

8. The method of claim 2, further comprising:

determining the temperature of the patient relative to a predetermined range;

determining the temperature of the thermal exchange device; and

reducing the circulation of heat exchange fluid the thermal exchange device and the body of the patient when the temperature of the body of the patient is greater than the predetermined range and is greater than the temperature of the thermal exchange device.

9. The method of claim 1, wherein the first heat transfer rate is one of cooling or heating the body of the patient, and the second heat transfer rate is the other of cooling or heating the body of the patient.

10. The method of claim 1, wherein both the first and second heat transfer rates comprise cooling the body of the patient.

11. The method of claim 1, wherein the thermal device comprises:

the heat exchange fluid bath;

the fluid circuit adapted to contain the circulating heat exchange fluid in heat exchange relationship with the fluid bath and the catheter;

the pump operable to circulate the heat exchange fluid in the fluid circuit; and

a controller adapted to control the pump, wherein the circulation of the heat exchange fluid in the fluid circuit stops circulating between the fluid bath and the patient during a change in the temperature of the fluid bath between a first level and a second level when the catheter is implanted in the patient.

12. The method of claim 1, wherein both the first and second heat transfer rates comprise heating the body of the patient.

13. A method for changing the temperature of the body of a patient using a catheter in heat exchange relationship with a fluid bath, the method comprising:

establishing a first fluid bath temperature;

when the fluid bath is at the first fluid bath temperature, transferring heat between the fluid bath and the body of the patient by circulating a heat exchange fluid in heat exchange relationship with the catheter and the fluid bath;

stopping the circulation of fluid when a target temperature is reached and leaving the catheter in the patient;

establishing a second fluid bath temperature; and

when the fluid bath is at the second fluid bath temperature, restarting the circulation of fluid and transferring heat between the fluid bath and the body of the patient.

14. The method of claim 13, wherein is performed when the temperature of the body of the patient is greater than a predetermined range but is less than the temperature of the fluid bath.

15. The method of claim 13, further comprising reducing the circulation rate of the heat exchange fluid to a vanishingly low level.

16. The method of claim 13, further comprising stopping the circulation of fluid when a target temperature is reached and leaving the catheter in the patient when the temperature of the body of the patient is less than a predetermined range and is less than the temperature of the fluid bath.

17. The method of claim 13, wherein the direction of heat transfer is the same at both the first and second fluid bath temperatures.

18. The method of claim 13, wherein the direction of heat transfer at the first fluid bath temperature is different from the direction of heat transfer at the second fluid bath temperature.

19. The method of claim 13, wherein stopping the pump when a target temperature is reached and leaving the catheter in the patient is performed when the temperature of the body of the patient is less than a predetermined range but is greater than the temperature of the fluid bath.

20. The method of claim 13, further comprising a pump operable to circulate the heat exchange fluid in the fluid circuit and stopping the circulation of the heat exchange fluid by stopping the pump when a target temperature is reached and leaving the catheter in the patient is performed when the temperature of the body of the patient is greater than a predetermined range and is greater than the temperature of the fluid bath.

21. The method of claim 13, further comprising a pump operable to circulate the heat exchange fluid in the fluid circuit.

22. The method of claim 21, further comprising stopping the circulation of the heat exchange fluid by stopping the pump.

23. A method for changing the temperature of the body of a patient comprising:

implanting a catheter into the body of the patient;

circulating a heat exchange fluid in heat exchange relationship between the patient and a fluid bath at a first transfer rate;

stopping the circulation of the heat exchange fluid between the patient and the fluid bath when a target temperature is reached and leaving the catheter in the patient;

slewing the fluid bath;

restarting the circulation of the heat exchange fluid; and

circulating the heat exchange fluid between the catheter and the fluid bath at a second transfer rate.

24. The method of claim 23, further comprising a pump operable for stopping the circulation of the heat exchange fluid when the target temperature is reached.