Optical measurement system for living bodies and method thereof
First Claim
1. An optical measurement method comprising the steps of:
- irradiating a plurality of regions on a surface of a subject'"'"'s head with light;
detecting an amount of transmitted light in a plurality of regions separated by a predetermined distance from the incident regions;
applying a predefined stimulus/task instruction sequence to a subject;
using the stimulus/task instruction sequence as a reference phase signal to calculate a synchronization index indicating the synchronousness of the phase of a signal, which represents a detected amount of transmitted light, with the reference phase signal;
adopting as a second reference phase signal a signal which represents an amount of transmitted light and whose phase is found based on a synchronization index, which indicates the synchronousness of the phase of the signal, to be most highly synchronous with the reference phase signal;
calculating a synchronization index indicating the synchronousness of the phase of a signal, which represents a detected amount of transmitted light, with the phase of the second reference phase signal; and
outputting to a display only a signal, which represents a detected amount of transmitted light and of which the synchronization index indicating the synchronousness of the phase thereof with the phase of the second reference phase signal is equal to or larger than a predetermined threshold, as a measured value indicating a brain activity of the subject.
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Accused Products
Abstract
A response period is determined arbitrarily. A satisfactory detecting ability may not be provided because of an artifact or the like contained in a signal. Therefore, an effective detection method and an effective display method of presenting results of detection must be developed. A series of tasks (stimuli) or a selected measurement signal is used as a reference signal, and a phase difference of any other measurement signal from the reference signal is calculated. The synchronousness of the phase of the measurement signal with the phase of the reference signal is numerically expressed. The thus obtained numerical value is statistically processed in order to numerically express a degree of reliability. Thus, a brain activity or a functional connectivity is visualized.
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Citations
7 Claims
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1. An optical measurement method comprising the steps of:
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irradiating a plurality of regions on a surface of a subject'"'"'s head with light; detecting an amount of transmitted light in a plurality of regions separated by a predetermined distance from the incident regions; applying a predefined stimulus/task instruction sequence to a subject; using the stimulus/task instruction sequence as a reference phase signal to calculate a synchronization index indicating the synchronousness of the phase of a signal, which represents a detected amount of transmitted light, with the reference phase signal; adopting as a second reference phase signal a signal which represents an amount of transmitted light and whose phase is found based on a synchronization index, which indicates the synchronousness of the phase of the signal, to be most highly synchronous with the reference phase signal; calculating a synchronization index indicating the synchronousness of the phase of a signal, which represents a detected amount of transmitted light, with the phase of the second reference phase signal; and outputting to a display only a signal, which represents a detected amount of transmitted light and of which the synchronization index indicating the synchronousness of the phase thereof with the phase of the second reference phase signal is equal to or larger than a predetermined threshold, as a measured value indicating a brain activity of the subject.
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2. An optical measurement system comprising:
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means for irradiating a plurality of regions on a surface of a subject'"'"'s head with light; means for detecting an amount of transmitted light in a plurality of regions separated by a predetermined distance from the incident regions; means for applying a predefined stimulus/task instruction sequence to a subject; means for using the stimulus/task instruction sequence as a reference phase signal to calculate a synchronization index indicating synchronousness of the phase of a signal, which represents a detected amount of transmitted light, with the phase of the reference phase signal, and transmitting a signal, which represents a detected amount of transmitted light and of which the synchronization index indicating the synchronousness of the phase thereof is equal to or larger than a predetermined threshold, as a measured value indicating a brain activity of the subject; and means for displaying an output of the transmitting means. - View Dependent Claims (3)
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4. An optical measurement system comprising:
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a means for irradiating a plurality of regions on a surface of a subject'"'"'s head with light; a means for detecting an amount of transmitted light in a plurality of regions separated by a predetermined distance from the incident regions; a means for applying a predefined stimulus/task instruction sequence to a subject; and a means for using the stimulus/task instruction sequence as a reference phase signal to calculate a synchronization index indicating the synchronousness of the phase of a signal, which represents a detected amount of transmitted light, with the phase of the reference phase signal, transmitting only a signal, which represents a detected amount of transmitted light and of which the synchronization index indicating the synchronousness of the phase thereof is equal to or larger than a predetermined threshold, as a measured value indicating a brain activity of the subject, and visualizing the signal, which represents the measured value, by displaying an image at a position in an image, which expresses the subject'"'"'s head, associated with the measured position. - View Dependent Claims (5, 6, 7)
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Specification