Device for implanting a row of radioactive seeds and non-radioactive spacers in an animal body

• US 7,288,061 B2
• Filed: 10/01/2003
• Issued: 10/30/2007
• Est. Priority Date: 10/07/2002
• Status: Expired due to Fees

• Current Assignee: Nucletron Operations BV
• Original Assignee: Nucletron Holding BV (New Nucletron Company BV)
• Inventors: Kindlein, Johann, Visscher, Arie Luite, Schuurman, Jeroen, Lutz, Ulrike, Adam, Mark Alexander
• Primary Examiner(s): Lacyk; John P.
• Application Number:
  US10/674,356
• Publication Number:
  US 20050177020A1
• Time in Patent Office: 1,490 Days
• Field of Search: 600 1- 8, 600/431, 600433-435, 604/48, 604 57- 63, 604/93.01, 604/117, 604/264, 604/265, 604/272, 604/890.1, 604/891.1
• US Class Current: 600/3
• CPC Class Codes: A61N 2005/1011 Apparatus for permanent insertion of sources
• CPC Class Codes: A61N 2005/1023 Means for creating a row of seeds, e.g. spacers
• CPC Class Codes: A61N 5/1007 Arrangements or means for the introduction of sources into the body

Abstract

A device for implanting radioactive seeds and non-radioactive spacers in a desired configuration in an animal body for effecting radiation therapy. An elongated hollow needle is inserted in the body. A pushing element implants the row of seeds and spacers though the hollow needle towards the desired location. A tube shaped element receives the row of seeds and spacers. A lube shaped sleeve having open ends is used to insert the tube shaped element through the needle and toward the location. The pushing elements pushes the row of seeds and spacers into the desired location while still being carried in the tube shaped element.

Claims

1. Device for implanting at least one row of X radioactive seeds and Y non-radioactive spacers with X∈

[1, 2, . . . ] and Y∈

[0, 1, . . . ] in a desired configuration to a desired location in an animal body for effecting radiation therapy of cancerous tissue in said body, said device comprising;

a) at least one elongated hollow needle with an open distal end to be inserted towards said desired location in the body and with a proximal end to be connected to a seed loading apparatus;

b) at least one tube-shaped sleeve member with an open distal end and an open proximal end to be slidably received within said hollow needle toward said desired location;

c) at least one pushing element for implanting during retraction of the elongated hollow needle said row of radioactive seeds and non-radioactive spacers from said seed loading apparatus through said hollow needle and said tube-shaped sleeve member towards said location,

d) at least one tube-shaped element with at least one open end to be inserted by said tube-shaped sleeve member through said hollow needle towards said desired location; and

wherein

said tube-shaped element serves to accommodate said row of radioactive seeds and non-radioactive spacers after implantation.

2. Implanting device according to claim 1, wherein said tube-shaped element is inserted through said hollow needle prior to the insertion of the row of radioactive seeds and non-radioactive spacers.

3. Implanting device according to claim 1, wherein said pushing element is constructed as a rigid pushing rod.

4. Implanting device according to claim 1, wherein said pushing element is constructed as a drive wire of the seed loading apparatus.

5. Implanting device according to claim 1, wherein said tube-shaped sleeve member is provided at its proximal end with a stopper element.

6. Implanting device according to claim 5, wherein said stopper element is constructed as a disc shaped end plate.

7. Implanting device according to claim 1, wherein the outer dimensions of the tube-shaped sleeve member and the tube-shaped element are equal or slightly smaller than the inner dimensions of said hollow needle.

8. Implanting device according to claim 1, wherein the inner dimensions of the tube-shaped sleeve and the tube-shaped element are equal or slightly larger than the outer dimensions of said radioactive seed and non-radioactive spacer.

9. Implanting device according to claim 1, wherein

L≧

(X+Y)s and S≦

(L−

1),

in which

l is the length of the tube-shaped element;

s is the length of one individual seed/spacer;

L is the length of the hollow needle;

S is the length of the tube-shaped sleeve member.

10. Implanting device according to claim 1, wherein said tube-shaped element is made of a bio-absorbable material.

11. Implanting device according to claim 1, wherein the tube-shaped element has two open ends.

12. Implanting device according to claim 1, wherein the tube-shaped element has one closed distal end.

13. Implanting device according to claim 1, wherein prior to the insertion through the hollow needle the tube-shaped element has an oval-shaped cross section and a circular cross section when inserted in the hollow needle.

14. Implanting device according to claim 1, wherein the tube-shaped element has a circular cross section.

15. Implanting device according to claim 1, wherein the tube-shaped element is made of a flexible material for exerting an inwardly directed force on the row of radioactive seeds and non-radioactive spacers.

16. Implanting device according to claim 1, wherein at least the open end of said tube-shaped element is collapsable.

17. A seed loading apparatus provided with an implanting device according to claim 1.

18. A row of X radioactive seeds and Y non-radioactive spacers with X∈

[1, 2, . . . ] and Y∈

[0, 1, . . . ] in a desired configuration, wherein said seeds and spacers are accommodated in a tube-shaped element according to claim 1.