System for enhanced cardiac function with combined PESP/NES
First Claim
1. A method of applying stimulation pulse therapy to excitable tissue, comprising:
- delivering a post extrasystolic potentiation (PESP) stimulation therapy to the excitable tissue for a cardiac cycle;
delivering a non-excitatory stimulation (NES) stimulation therapy to the excitable tissue during certaincardiac cycles wherein the NES stimulation therapy is delivered on N of M cardiac cycles; and
determining physiologic demand of the patient based on at least one physiologic measurementwherein N is variable and is based on the determined physiologic demand.
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Accused Products
Abstract
In some embodiments, a method of applying stimulation pulse therapy to excitable tissue may include one or more of the following steps: (a) delivering a PESP stimulation therapy to the excitable tissue for a cardiac cycle, (b) delivering a NES stimulation therapy to the excitable tissue during certain cardiac cycles, (c) determining physiologic demand of the patient based on at least one physiologic measurement, (d) determining physiologic demand being placed on a heart based on at least one physiologic measurement, and ceasing the delivery of the NES and PESP stimulation therapy when physiologic demand returns to a base level, and (e) determining physiologic demand being placed on a heart based on at least one physiologic measurement, and modulating the ratio of the number of cardiac cycles in which the NES stimulation therapy is delivered to the number of cardiac cycles in which the PESP stimulation therapy is delivered based on physiologic demand.
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Citations
6 Claims
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1. A method of applying stimulation pulse therapy to excitable tissue, comprising:
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delivering a post extrasystolic potentiation (PESP) stimulation therapy to the excitable tissue for a cardiac cycle; delivering a non-excitatory stimulation (NES) stimulation therapy to the excitable tissue during certaincardiac cycles wherein the NES stimulation therapy is delivered on N of M cardiac cycles; and determining physiologic demand of the patient based on at least one physiologic measurement wherein N is variable and is based on the determined physiologic demand. - View Dependent Claims (2, 3, 4)
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5. A method of applying stimulation pulse therapy to excitable tissue, comprising:
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delivering a PESP stimulation therapyto the excitable tissue for a cardiac cycle; delivering a NES stimulation therapy to the excitable tissue during certain cardiac cycles; determining physiologic demand being placed on a heart based on at least one physiologic measurement, and ceasing the delivery of the NES and PESP stimulation therapy when physiologic demand returns to a base level.
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6. A method of applying stimulation pulse therapy to excitable tissue, comprising:
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delivering a PESP stimulation therapy to the excitable tissue for a cardiac cycle; delivering a NES stimulation therapy to the excitable tissue during certain cardiac cycles; determining physiologic demand being placed on a heart based on at least one physiologic measurement, and modulating the ratio of the number of cardiac cycles in which the NES stimulation therapy is delivered to the number of cardiac cycles in which the PESP stimulation therapy is delivered based on physiologic demand.
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Specification