Method and apparatus for control of non-invasive parameter measurements
First Claim
1. A method of continuously and non-invasively measuring blood pressure in a living subject, comprising:
- tonometrically measuring pressure from a blood vessel at a first location on said subject using at least one sensor, said act of measuring further comprising controllably applanating said blood vessel using said at least one sensor;
at least partly occluding a blood vessel at a second location on said subject, said second location being ipsilateral to said first location, said act of occluding having at least some effect on said act of measuring;
detecting, based at least in part on said effect, that said act of at least partly occluding is occurring; and
adjusting said act of measuring in order to mitigate said effect.
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Accused Products
Abstract
Improved methods and apparatus for non-invasively assessing one or more parameters associated with fluidic systems such as the circulatory system of a living organism, when such parameters are potentially affected by other concurrent events. In one exemplary embodiment, apparatus and methods for compensating for occlusive events (e.g., pressure cuff inflation) occurring ipsilateral to the location of parameter measurement are disclosed. Upon passive detection of signal degradation resulting from the event, the apparatus selectively enters a “wait state” wherein further processing of the hemodynamic data is suspended until the degrading event subsides. This behavior mitigates any adverse effects the event might have on the accuracy of the representation of the measured hemodynamic parameter generated by the system. In another exemplary embodiment, the measured data is analyzed in order to classify the type of event (e.g., occlusive or other), such classification allowing the system to appropriately tailor its response to the event.
64 Citations
24 Claims
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1. A method of continuously and non-invasively measuring blood pressure in a living subject, comprising:
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tonometrically measuring pressure from a blood vessel at a first location on said subject using at least one sensor, said act of measuring further comprising controllably applanating said blood vessel using said at least one sensor; at least partly occluding a blood vessel at a second location on said subject, said second location being ipsilateral to said first location, said act of occluding having at least some effect on said act of measuring; detecting, based at least in part on said effect, that said act of at least partly occluding is occurring; and adjusting said act of measuring in order to mitigate said effect. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method of measuring blood pressure in a living subject, comprising:
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measuring pressure from a blood vessel at a first location on said subject; at least partly occluding a blood vessel at a second location on said subject, said act of occluding having at least some effect on said act of measuring; and adjusting said act of measuring based at least in part on said effect; wherein said act of adjusting comprises ceasing ongoing adjustment of applanation pressure to said first location for at least a first period. - View Dependent Claims (11, 12)
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13. A method of measuring blood pressure in a living subject, comprising:
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measuring pressure from a blood vessel at a first location on said subject; at least partly occluding a blood vessel at a second location on said subject, said act of occluding having at least some effect on said act of measuring; and adjusting said act of measuring based at least in part on said effect; wherein said act of adjusting comprises; identifying a lack of useful pressure data obtained from said act of measuring; and delaying subsequent corrective measures for reacquiring useful data for at least a first period.
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14. A method of measuring blood pressure in a living subject, comprising:
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measuring pressure from a blood vessel at a first location on said subject; at least partly occluding a blood vessel at a second location on said subject, said act of occluding having at least some effect on said act of measuring; and adjusting said act of measuring based at least in part on said effect;
wherein said act of adjusting comprises;passively determining a change in at least one parameter associated with data generated from said measurement of blood pressure; and adjusting processing of said data based on said determining, said adjusting at least in part mitigating said effects from said occluding of said blood vessel. - View Dependent Claims (15)
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16. A method of measuring blood pressure in a living subject, comprising:
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measuring pressure from a blood vessel at a first location on said subject; at least partly occluding a blood vessel at a second location on said subject, said act of occluding having at least some effect on said act of measuring; and adjusting said act of measuring based at least in part on said effect; wherein said act of measuring comprises (i) obtaining first pressure data corresponding to a normal or non-event state of operation, and (ii) obtaining second pressure data corresponding to a second state during said at least partial occlusion of said blood vessel, said at least partial occlusion resulting in at least some degradation of said pressure data; and wherein said act of adjusting further comprises evaluating at least one metric associated with said first and second pressure data. - View Dependent Claims (17, 18)
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19. A method of measuring blood pressure in a living subject, comprising:
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tonometrically measuring pressure from a blood vessel at a first location on said subject; at least partly occluding a blood vessel at a second location on said subject, said act of occluding having at least some effect on said act of measuring; and adjusting said act of measuring based at least in part on said effect, said act of adjusting comprising; sensing pressure at said first location using at least one sensor, and generating signals relating thereto; passively detecting a degradation of said signals; classifying said degradation based at least in part on said signals; and compensating for the effects of said degradation during further of said measuring. - View Dependent Claims (20)
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21. Apparatus for measuring blood pressure in a living subject, comprising:
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apparatus configured to tonometrically measure pressure from the radial artery of said subject; and apparatus adapted to adjust said measurement based at least in part on an effect, said effect resulting at least in part from at least partly occluding a blood vessel ipsilateral using an inflatable cuff on said radial artery of said subject; wherein said apparatus adapted to adjust comprises apparatus adapted to identify a lack of useful pressure data obtained from said tonometric measurement of pressure and delay subsequent corrective measures for reacquiring useful data for at least a first period. - View Dependent Claims (22)
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23. Apparatus for measuring blood pressure in a living subject, comprising:
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apparatus configured to tonometrically measure pressure from the radial artery of said subject; and apparatus adapted to adjust said measurement based at least in part on an effect, said effect resulting at least in part from at least partly occluding a blood vessel ipsilateral to said radial artery on said subject; wherein said apparatus adapted to adjust said measurement is configured to adjust the measurement at least in part via an applanation mechanism, said adjustment comprising ceasing ongoing adjustment of applanation pressure to said radial artery for at least a first period; wherein said apparatus adapted to adjust further comprises apparatus adapted to identify a lack of useful pressure data obtained from said tonometric measurement of pressure and delay subsequent corrective measures for reacquiring useful data for at least a first period. - View Dependent Claims (24)
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Specification