Medical device for delivering biologically active material
First Claim
1. A medical device for delivering a biologically active material to a body tissue of a patient in need of treatment, wherein the medical device comprises a tubular portion comprising an outer surface;
- a plurality of struts that form a plurality of openings;
a plurality of non-structural elements integral with and projecting from the struts into the openings, wherein the non-structural elements are distributed throughout the outer surface; and
a coating comprising a biologically active material disposed on the struts and the non-structural elements.
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Accused Products
Abstract
A medical device for delivering a biologically active material into a body tissue, comprising struts and optionally the biologically active material. In an embodiment, the medical device comprises non-structural elements integral with the struts. A method for designing such medical device are also disclosed. Another embodiment is a medical device having an outer surface comprising a middle section and end sections. The end sections have a greater available surface area, greater affinity for or a greater amount of the biologically active material per unit length of the outer surface than the middle section. The middle section may be covered with a barrier layer. Another embodiment is a medical device comprising a rectangular portion having a greater capacity for carrying a biologically active material per unit length of the outer surface. A method for delivering a biologically active material to a body tissue is also disclosed.
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Citations
15 Claims
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1. A medical device for delivering a biologically active material to a body tissue of a patient in need of treatment, wherein the medical device comprises a tubular portion comprising an outer surface;
- a plurality of struts that form a plurality of openings;
a plurality of non-structural elements integral with and projecting from the struts into the openings, wherein the non-structural elements are distributed throughout the outer surface; and
a coating comprising a biologically active material disposed on the struts and the non-structural elements. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
- a plurality of struts that form a plurality of openings;
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12. A medical device for delivering a biologically active material to a body tissue of a patient in need of treatment, wherein the medical device comprises a plurality of struts that form a plurality of openings;
- a plurality of non-structural elements integral with and projecting from the struts into the openings; and
a coating comprising a biologically active material disposed on the struts and the non-structural elements, wherein the biologically active material is selected from the group consisting of paclitaxel, actinomycin, sirolimus, tacrolimus, everolimus, dexamethasone, halofuginone and hydrophobic nitric oxide adducts. - View Dependent Claims (13, 14, 15)
- a plurality of non-structural elements integral with and projecting from the struts into the openings; and
Specification