×

Anti-IL-6 antibodies, compositions, methods and uses

  • US 7,291,721 B2
  • Filed: 10/26/2002
  • Issued: 11/06/2007
  • Est. Priority Date: 11/14/2001
  • Status: Active Grant
First Claim
Patent Images

1. Isolated nucleic acid molecules encoding an antibody or antigen-binding fragment thereof that binds and inhibits the activity of human IL-6, wherein said antibody or antigen-binding fragment comprise:

  • a human antibody heavy chain constant region and a heavy chain variable region comprising CDR1, CDR2 and CDR3, which comprise the amino acid sequences SEQ ID NO;

    1, SEQ ID NO;

    2 and SEQ ID NO;

    3, respectively; and

    a human antibody light chain constant region and a light chain variable region comprising CDR1, CDR2 and CDR3, which comprise the amino acid sequences SEQ ID NO;

    4, SEQ ID NO;

    5 and SEQ ID NO;

    6, respectively.

View all claims
  • 4 Assignments
Timeline View
Assignment View
    ×
    ×