Vagus nerve stimulation via unidirectional propagation of action potentials
First Claim
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1. Method of stimulating a vagus nerve, the method comprising:
- providing at least one implantable stimulator with at least two electrodes, at least one of the electrodes comprising a leadless electrode;
configuring the electrodes, including the leadless electrode, to apply stimulation that unidirectionally propagates action potentials along a vagus nerve; and
applying the stimulation to the vagus nerve using the electrodes, including the leadless electrode, to effectively select afferent fibers, thereby treating at least one of epilepsy and depression while limiting side effects of bidirectional stimulation.
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Abstract
Methods of stimulating a vagus nerve include providing at least one implantable stimulator with at least two electrodes, configuring the electrodes to apply stimulation that unidirectionally propagates action potentials along a vagus nerve, and applying the stimulation to the vagus nerve to effectively select afferent fibers, thereby treating at least one of epilepsy and depression while limiting side effects of bidirectional stimulation. At least one of the electrodes comprises a leadsless electrode.
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Citations
24 Claims
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1. Method of stimulating a vagus nerve, the method comprising:
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providing at least one implantable stimulator with at least two electrodes, at least one of the electrodes comprising a leadless electrode; configuring the electrodes, including the leadless electrode, to apply stimulation that unidirectionally propagates action potentials along a vagus nerve; and applying the stimulation to the vagus nerve using the electrodes, including the leadless electrode, to effectively select afferent fibers, thereby treating at least one of epilepsy and depression while limiting side effects of bidirectional stimulation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. Method of stimulating a vagus nerve, the method comprising:
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providing at least one implantable stimulator with at least two leadless electrodes; configuring the electrodes, including the leadless electrode, to apply stimulation that unidirectionally propagates action potentials along a vagus nerve; and applying the stimulation to the vagus nerve using the electrodes, including the leadless electrode, to effectively select orthodromic action potentials in afferent fibers, thereby treating at least one of epilepsy and depression while limiting side effects of bidirectional stimulation. - View Dependent Claims (15, 16, 17, 18, 19, 20)
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21. Method of stimulating a vagus nerve, the method comprising the steps of:
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providing at least one implantable stimulator with at least two electrodes, at least one or the electrodes comprising a partitioned leadless electrode that includes two or more sections; configuring the electrodes, including the leadless electrode, to apply stimulation that unidirectionally propagates action potentials along a vagus nerve; applying the stimulation to the vagus nerve using the electrodes, including the leadless electrode to effectively select orthodromic action potentials in afferent fibers, thereby treating at least one of epilepsy and depression while limiting side effects of bidirectional stimulation. - View Dependent Claims (22, 23, 24)
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Specification