Method of stimulating/sensing brain with combination of intravascularly and non-vascularly delivered leads

• US 7,295,875 B2
• Filed: 02/20/2004
• Issued: 11/13/2007
• Est. Priority Date: 02/20/2004
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Garabedian, Robert J., Wallace, Michael P.
• Primary Examiner(s): Evanisko; George R.
• Assistant Examiner(s): HOLMES, REX R
• Application Number:
  US10/783,679
• Publication Number:
  US 20050187589A1
• Time in Patent Office: 1,362 Days
• Field of Search: 607/1, 607/2, 607/45, 607/116, 600/378, 600/898
• US Class Current: 607/45
• CPC Class Codes: A61N 1/0529 Electrodes for brain stimulation
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/36017 with leads or electrodes penetrating the skin
• CPC Class Codes: A61N 1/36025 for treating a mental or cerebral condition
• CPC Class Codes: A61N 1/36064 Epilepsy
• CPC Class Codes: A61N 1/36067 Movement disorders, e.g. tremor or Parkinson disease stimulating motor muscle A61N1/36003
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease

Abstract

A method of treating a neurological disorder in a patient is provided. The method comprises intravascularly delivering a first electrical lead within the head of the patient, and non-vascularly delivering a second electrical lead within the head the patient. The vascular and intravascular leads are placed adjacent brain tissue (e.g., cortical brain tissue or deep brain tissue). Optionally, the method comprises implanting a source of stimulation and/or recorder within the patient'"'"'s body, and then electrically coupling the proximal ends of the electrical leads to the implanted device. Using the electrical leads, the brain tissue can then be stimulated and/or recorded in order to treat the neurological disorder.

Claims

1. A medical method performed on a patient, comprising:

intravascularly delivering a first electrical lead within the head of the patient;

non-vascularly delivering a second electrical lead within the head of the patient;

placing one of the first electrical lead and the second electrical lead adjacent a first brain tissue region;

placing another of the first electrical lead and the second electrical lead adjacent a second brain tissue region;

stimulating the first brain tissue region with the one of the first electrical lead and the second electrical lead to treat a neurological disorder of the patient; and

recording brain signals at the second brain tissue region with the other of the first electrical lead and the second electrical lead to monitor the neurological disorder.

2. The method of claim 1, wherein the neurological disorder is a degenerative disorder.

3. The method of claim 1, wherein the neurological disorder is a brain infarction.

4. The method of claim 1, wherein the first electrical lead is introduced into the head via the circulatory system.

5. The method of claim 1, wherein the first electrical lead is introduced into the head via the ventricular system.

6. The method of claim 1, wherein the first electrical lead is placed in direct contact with the brain tissue.

7. The method of claim 1, wherein the first electrical lead is placed in indirect contact with the brain tissue.

8. The method of claim 1, wherein the first electrical lead is placed adjacent cortical brain tissue, and the second electrical lead is placed adjacent deep brain tissue.

9. The method of claim 1, wherein the first electrical lead is placed adjacent deep brain tissue, and the second electrical lead is placed adjacent cortical brain tissue.

10. The method of claim 1, further comprising:

electrically connecting the one of the first electrical lead and the second electrical lead to a stimulation source; and

electrically connecting the other of the first electrical lead and the second electrical lead to a recorder.

11. The method of claim 10, further comprising implanting the stimulation source and the recorder within the patient.

23. The method of claim 1, wherein the one of the first electrical lead and the second electrical lead is the second electrical lead, and the other of the first electrical lead and the second electrical lead is the first electrical lead.

24. The method of claim 23, wherein the first electrical lead records the brain signals from within the sagittal sinus of the patient.

25. The method of claim 1, wherein the neurological disorder is epilepsy.

26. The method of claim 1, wherein the brain signals recorded at the second brain tissue region by the other of the first electrical lead and the second electrical lead indicate the onset of a seizure, and the one of the first electrical lead and the second electrical lead stimulates the first brain tissue region to stop the seizure.

12. A medical method performed on a patient, comprising:

delivering a first electrical lead within the head of the patient via a blood vessel;

delivering a second electrical lead within the head of the patient via an opening in an cranium of the patient; and

placing one of the first electrical lead and the second electrical lead adjacent a first brain tissue region;

placing another of the first electrical lead and the second electrical lead adjacent a second brain tissue region;

stimulating the first brain tissue region with the one of the first electrical lead and the second electrical lead to treat a neurological disorder of the patient; and

recording brain signals at the second brain tissue region with the other of the first electrical lead and the second electrical lead to monitor the neurological disorder.

13. The method of claim 12, wherein the neurological disorder is a degenerative disorder.

14. The method of claim 12, wherein the neurological disorder is a brain infarction.

15. The method of claim 12, wherein the blood vessel is a vein.

16. The method of claim 12, wherein the blood vessel is an artery.

17. The method of claim 12, wherein the first electrical lead is placed in direct contact with the brain tissue.

18. The method of claim 12, wherein the first electrical lead is placed in indirect contact with the brain tissue.

19. The method of claim 12, wherein the first electrical lead is placed adjacent cortical brain tissue, and the second electrical lead is placed adjacent deep brain tissue.

20. The method of claim 12, wherein the first electrical lead is placed adjacent deep brain tissue, and the second electrical lead is placed adjacent cortical brain tissue.

21. The method of claim 12, further comprising:

electrically connecting the one of the first electrical lead and the second electrical lead to a stimulation source; and

electrically connecting the other of the first electrical lead and the second electrical lead to a recorder.

22. The method of claim 21, further comprising implanting the stimulation source and the recorder within the patient.

27. The method of claim 12, wherein the one of the first electrical lead and the second electrical lead is the second electrical lead, and the other of the first electrical lead and the second electrical lead is the first electrical lead.

28. The method of claim 27, wherein the first electrical lead records the brain signals from within the sagittal sinus of the patient.

29. The method of claim 12, wherein the neurological disorder is epilepsy.

30. The method of claim 12, wherein the brain signals recorded at the second brain tissue region by the other of the first electrical lead and the second electrical lead indicate the onset of a seizure, and the one of the first electrical lead and the second electrical lead stimulates the first brain tissue region to stop the seizure.