Method and apparatus for providing positive airway pressure to a patient

• US 7,296,573 B2
• Filed: 07/15/2005
• Issued: 11/20/2007
• Est. Priority Date: 06/03/1994
• Status: Expired due to Term

• Current Assignee: RIC INVESTMENTS LLC (Koninklijke Philips N.V.)
• Original Assignee: RIC INVESTMENTS LLC (Koninklijke Philips N.V.)
• Inventors: Kepler, Jeff, Estes, Mark C., Fiore, John, Mechlenburg, Douglas M., Ressler, Heather
• Primary Examiner(s): Yu; Justine R.
• Assistant Examiner(s): Matter; Kristen
• Application Number:
  US11/182,387
• Publication Number:
  US 20050247315A1
• Time in Patent Office: 858 Days
• Field of Search: 128/204.18, 128/204.21, 128/204.23, 128/204.26
• US Class Current: 128/204.23
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/0066 Blowers or centrifugal pumps
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/204 used for inhalation control
• CPC Class Codes: A61M 16/205 used for exhalation control
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2016/0036 in the breathing tube and used in both inspiratory and expiratory phase
• CPC Class Codes: A61M 2016/0039 in the inspiratory circuit

Abstract

A system including methods and apparatus for treatment of a medical disorder such as obstructive sleep apnea or congestive heart failure. The system involves applying a gain to flow rate of pressurized gas delivered to a patient during inspiratory and/or expiratory phases of a respiratory cycle to deliver the pressurized gas in proportion to the respective gains during inspiration and/or expiration. A base pressure may be applied in addition to the gain-modified pressures and an elevated pressure profile may be employed to assist or control inspiration. The system may be fully automated responsive to feedback provided by a flow sensor that determines the estimated patient flow rate. A leak computer can be included to instantaneously calculate gas leakage from the system. The system may be utilized in connection with conventional continuous positive airway pressure treatments, such as CPAP or bi-level positive airway pressure equipment to effect various beneficial treatment applications.

Claims

1. A method of delivering pressurized gas to an airway of a patient, comprising the steps of:

providing a gas flow generator and a patient interface adapted to couple the gas flow generator to an airway of a patient;

delivering a flow of gas to such a patient using the gas flow generator and the patient interface;

differentiating between an expiratory phase and an inspiratory phase of a respiratory cycle of such a patient;

establishing a reduced pressure profile for a pressure of the flow of gas provided to the patient, where the reduced pressure profile has a contour that is predetennined prior to initiation of the expiratory phase and is detennined independent of operating characteristics of the gas flow generator, and wherein the contour defines a changing pressure over a period of time; and

controlling the gas flow delivered to such a patient so that (1) the pressure of the flow of gas is provided at a first pressure level during at least a portion of the inspiratory phase, and (2) the pressure of the flow of gas is provided according to the reduced pressure profile during at least a portion of the expiratory phase of the respiratory cycle.

2. The method of claim 1, further comprising a step of setting a magnitude, a duration, or both of the reduced pressure profile.

3. The method of claim 1, further comprising manually selecting the contour, a magnitude a duration, or any combination thereof.

4. The method of claim 1, wherein the contour of the reduced pressure profile drops off quickly at the start of expiration and rises slowly toward the first pressure level.

5. The method of claim 1, wherein the fist pressure level corresponds to a CPAP pressure.

6. The method of claim 1, wherein the reduced pressure profile is provided during an entirety of the expiratory phase of the respiratory cycle.

7. The method of claim 1, further comprising receiving an input from a manual input device, wherein the contour, a magnitude, or both of the reduced pressure profile are determined based on the input.

8. The method of claim 1, wherein the contour is followed during a central portion of the expiratory phase.

9. An apparatus for delivering pressurized gas to an airway of a patient, the apparatus comprising:

(a) blower;

(b) conduit adapted to carry a flow of gas generated by the blower to an airway of a patient;

(c) sensor adapted to monitor a characteristic associated with the gas in the conduit or a flow of the gas;

(d) signal related to the characteristic;

(e) a pressure controller associated with the blower, the conduit, or both to control a pressure of the gas in the conduit; and

(f) a processor adapted to (1) establish a reduced pressure profile for a pressure of the flow of gas provided to the patient, where the reduced pressure profile has a contour that is predetermined prior to initiation of the expiratory phase and is determined independent of operating characteristics of the gas flow generator, and wherein the contour defines a changing pressure over a period of time, and (2) control the pressure controller so that the pressure of the flow of gas is provided to a patient at (a) a first pressure level during at least a portion of an inspiratory phase of a respiratory cycle, and (b) in accordance with the reduced pressure profile during at least a portion of an expiratory phase of the respiratory cycle.

10. The apparatus of claim 9, further comprising an input device adapted to set a magnitude, a duration, or both of the reduced pressure profile.

11. The apparatus of claim 9, wherein the contour of the reduced pressure profile drops off quickly at the start of expiration and rises slowly toward the first pressure level.

12. The apparatus of claim 9, wherein the fist pressure level corresponds to a CPAP pressure.

13. The apparatus of claim 9, wherein the reduced pressure profile is provided during an entirety of the expiratory phase of the respiratory cycle.

14. The apparatus of claim 9, further comprising an input device, wherein the contour, a magnitude, or both of the reduced pressure profile are determined based on an input provided by the input device.

15. The apparatus of claim 9, wherein the contour is followed during a central portion of the expiratory phase.

16. A method of providing pressured gas to an airway of a patient, the method comprising the steps of:

providing a gas flow generator;

coupling the gas flow generator to an airway of a patient;

delivering a flow of gas to the airway of such a patient from the gas flow generator;

monitoring a characteristic associated with the flow of gas;

providing a signal related to the characteristic;

selecting a first gain; and

controlling the flow of gas to such a patient such that the flow of gas is delivered to a patient at (1) a therapy pressure during at least a portion of an inspiratory portion of a respiratory cycle, wherein the therapy pressure is a pressure sufficient to counter airway collapsing forces, and (2) based on the first gain and the signal during at least a portion of an expiratory phase of a respiratory cycle.

17. The method of claim 16, wherein the controlling step includes controlling the pressure so as to prevent pressure oscillations during expiration.

18. The method of claim 16, wherein the therapy pressure corresponds to a CPAP pressure.

19. The method of claim 16, wherein the controlling steps includes (1) providing a first pressure during at least a portion of an inspiratory phase of a patient'"'"'s respiratory cycle and (2) providing a second pressure during at least a portion of an expiratory phase of a respiratory cycle, wherein the second pressure is lower than the first pressure and is further reduced by an amount based on the first gain and the signal.

20. The method of claim 16, wherein controlling the flow of gas to such a patient is done based on the first gain and the signal during an entirety of the expiratory phase of the respiratory cycle.

21. The method of claim 16, wherein the controlling step includes limiting a rate of change for the pressure of the gas.

22. The method of claim 21, wherein the controlling step includes setting a first rate of change limit for an increase in the pressure of the gas and setting second rate of change limit for a decrease in the pressure of the gas.

23. The method of claim 16, further comprising smoothing transitions between changes in a pressure of the gas.

24. An apparatus for delivering pressurized gas to an airway of a patient, the apparatus comprising:

a blower;

a conduit adapted to carry a flow of gas generated by the blower to the airway of the patient;

a sensor adapted to monitor a characteristic associated with the gas in the conduit or a flow of the gas;

a signal related to the characteristic;

a pressure controller associated with the blower or the conduit to control a pressure of the gas in the conduit;

a processor, responsive to the signal, to control the pressure controller so as to cause the gas to be delivered to a patient at a therapy pressure during at least a portion of an inspiratory portion of a respiratory cycle, wherein the therapy pressure is a pressure sufficient to counter airway collapsing forces; and

an input device, operatively connected to the processor, to select a first gain, wherein the processor controls the pressure controller so that the pressure of the gas in the conduit during at least a portion of an expiratory portion of the respiratory cycle is based on the first gain and the signal.

25. The apparatus of claim 24, wherein the processor controls the pressure controller so as to prevent pressure oscillations during expiration.

26. The apparatus of claim 24, wherein the therapy pressure corresponds to a CPAP pressure.

27. The apparatus of claim 24, wherein the processor controls the pressure controller to provide a first pressure during at least a portion of an inspiratory phase of a patient'"'"'s respiratory cycle and to provide a second pressure during at least a portion of an expiratory phase of the respiratory cycle, wherein the second pressure is lower than the first pressure and is further reduced by an amount based on the first gain and the signal.

28. The apparatus of claim 24, wherein the processor controls the flow of gas to such a patient based on the first gain and the signal during an entirety of the expiratory phase of the respiratory cycle.

29. The apparatus of claim 24, wherein the processor also limits a rate of change for the pressure of the gas in the conduit.

30. The apparatus of claim 29, wherein the processor sets a first rate of change limit for an increase in the pressure of the gas in the conduit and sets a second rate of change limit for a decrease in the pressure of the gas in the conduit.

31. The apparatus of claim 24, wherein the processor also smoothes transitions between changes in a pressure of the gas in the conduit.