Hydrophilic light absorbing compositions for determination of physiological function
First Claim
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1. A pharmaceutical composition comprising an effective amount of a radioactive halogen and a compound of Formula 2
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Abstract
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.
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Citations
6 Claims
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1. A pharmaceutical composition comprising an effective amount of a radioactive halogen and a compound of Formula 2
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2. A pharmaceutical composition comprising an effective amount of a radioactive metal ion and a compound of Formula 2
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3. A pharmaceutical composition comprising an effective amount of a compound of Formula 2
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4. A pharmaceutical composition comprising an effective amount of a contrast agent and a compound of Formula 2
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5. A pharmaceutical composition comprising an effective amount of a liposome, a micelle, a microcapsule, or a microparticle and a compound of Formula 2
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6. A pharmaceutical composition comprising an effective amount of at least one of monocrystalline iron oxide particles, silver particles, or gold particles and a compound of Formula 2
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