Medicament injection kit and medicament injection method

• US 7,297,475 B2
• Filed: 05/07/2004
• Issued: 11/20/2007
• Est. Priority Date: 05/16/2003
• Status: Active Grant

• Current Assignee: Terumo Kabushiki Kaisha
• Original Assignee: Terumo Kabushiki Kaisha
• Inventors: Tanaka, Tetsuo, Koiwai, Kazunori
• Primary Examiner(s): Nguyen; Quang
• Application Number:
  US10/840,600
• Publication Number:
  US 20040253212A1
• Time in Patent Office: 1,292 Days
• Field of Search: None
• US Class Current: 435/1.2
• CPC Class Codes: A61K 48/00 Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 25/10 Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00
• CPC Class Codes: A61M 31/00 Devices for introducing or retaining media, e.g. remedies, in cavities of the body A61M25/00 takes precedence ; introducing or retaining ophthalmic products into the ocular cavities A61F9/0008

Abstract

A medicament injection kit, for use in occluding a renal artery and a renal vein in a kidney and injecting a therapeutic medicament into the kidney so as to pressurize the kidney, includes: an artery catheter which includes a first balloon capable of occluding the renal artery; a vein catheter which includes a second balloon capable of occluding the renal vein; a syringe for injecting the therapeutic medicament, the syringe being capable of being connected to at least one of the artery catheter and the vein catheter; and a syringe for pressurizing the inside of the kidney by injecting a liquid, the syringe being capable of being connected to at least one of the artery catheter and the vein catheter.

Claims

1. A method of injecting a therapeutic medicament into a kidney, comprising:

(a) inserting a vein catheter including a first balloon into a renal vein, and occluding said renal vein by said first balloon;

(b) injecting said therapeutic medicament into said kidney from said vein catheter after (a);

(c) inserting an artery catheter including a second balloon into a renal artery, and occluding said renal artery by said second balloon after (b); and

(d) pressurizing said kidney by injecting a liquid into said kidney from said vein catheter or said artery catheter after (c).

2. A method as set forth in claim 1, wherein said liquid is a therapeutic medicament, physiological saline, Ringer'"'"'s solution, an infusion, or a mixture thereof.

3. A method as set forth in claim 1, wherein said therapeutic medicament is at least one selected from the group consisting of a polynucleotide, a gene, and a complex of a synthetic vector with a gene.

4. A method of injecting a therapeutic medicament into a kidney, comprising:

(a) inserting an artery catheter including a first balloon into a renal artery, and occluding said renal artery by said first balloon;

(b) injecting said therapeutic medicament into said kidney from said artery catheter after (a);

(c) inserting a vein catheter including a second balloon into a renal vein, and occluding said renal vein by said second balloon after (b); and

(d) pressurizing said kidney by injecting a liquid into said kidney from said artery catheter or said vein catheter after (c).

5. A method as set forth in claim 4, wherein said liquid is a therapeutic medicament, physiological saline, Ringer'"'"'s solution, an infusion, or a mixture thereof.

6. A method as set forth in claim 4, wherein said therapeutic medicament is at least one selected from the group consisting of a polynucleotide, a gene, and a complex of a synthetic vector with a gene.